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The map label for this gene is msrB [H]

Identifier: 78778400

GI number: 78778400

Start: 17768

End: 18262

Strand: Direct

Name: msrB [H]

Synonym: PMT9312_0015

Alternate gene names: 78778400

Gene position: 17768-18262 (Clockwise)

Preceding gene: 78778398

Following gene: 78778401

Centisome position: 1.04

GC content: 34.75

Gene sequence:

>495_bases
ATGAATCAATTTTTTTCAAGACGAACTTTCATTTTAATTCCTACTATGTCAATTTTAAAAATAATCTTTCAGCCTATGAA
AGTATTAGCTTCTTCATTCTCTTCCAAAGATGAGTGGAATTTATCAAAAGATGAATGGAAATCTAGGCTTAGTCCAGAAT
CTTATTATATTTTGAGGGAGGAAGGAACTGAAAGAGCTTTCAGTAGCGAATTAAATAATGAGAAAAGAAAAGGGGTGTTT
CATTGCGCAGGATGTGATTTACCACTATTTCTTTCAGATAAAAAGTATGATAGTGGTACTGGATGGCCAAGTTTTTGGGA
TCCAATTAAAGGATCAGTTGCAACAAAGGTTGATTTCAAGTTAATTGTCCCAAGAACCGAATATCACTGCTCTAGATGCG
GAGGTCATCAAGGACATGTCTTTAATGATGGGCCACTTCCTACAGGTAAAAGATACTGTAATAACGGATTAGCATTAAGG
TTTGTTCCTGAGTAA

Upstream 100 bases:

>100_bases
TTATCAGTACAATCCATCATTGGAGCAATACTTAATTTATGAATATTTTTAATAGAATTAGATTTAATAGAACTCATTAC
TTTTTATGTGATTTAAATAT

Downstream 100 bases:

>100_bases
AAATTTGTGCGGCCTTCCGCAACTTGTTTTGTGCCTCACTTTATTAGAAAATAGTTTTATTAAATTTTTAGAAAAATGAT
TGAAAATCAATCAGACAATA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MNQFFSRRTFILIPTMSILKIIFQPMKVLASSFSSKDEWNLSKDEWKSRLSPESYYILREEGTERAFSSELNNEKRKGVF
HCAGCDLPLFLSDKKYDSGTGWPSFWDPIKGSVATKVDFKLIVPRTEYHCSRCGGHQGHVFNDGPLPTGKRYCNNGLALR
FVPE

Sequences:

>Translated_164_residues
MNQFFSRRTFILIPTMSILKIIFQPMKVLASSFSSKDEWNLSKDEWKSRLSPESYYILREEGTERAFSSELNNEKRKGVF
HCAGCDLPLFLSDKKYDSGTGWPSFWDPIKGSVATKVDFKLIVPRTEYHCSRCGGHQGHVFNDGPLPTGKRYCNNGLALR
FVPE
>Mature_164_residues
MNQFFSRRTFILIPTMSILKIIFQPMKVLASSFSSKDEWNLSKDEWKSRLSPESYYILREEGTERAFSSELNNEKRKGVF
HCAGCDLPLFLSDKKYDSGTGWPSFWDPIKGSVATKVDFKLIVPRTEYHCSRCGGHQGHVFNDGPLPTGKRYCNNGLALR
FVPE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI37620216, Length=139, Percent_Identity=46.7625899280576, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI301336164, Length=148, Percent_Identity=45.2702702702703, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI301336162, Length=148, Percent_Identity=45.2702702702703, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI73089054, Length=148, Percent_Identity=45.2702702702703, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=47.0149253731343, Blast_Score=127, Evalue=5e-30,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=47.5409836065574, Blast_Score=119, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17553450, Length=129, Percent_Identity=39.5348837209302, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115532676, Length=129, Percent_Identity=39.5348837209302, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6319816, Length=138, Percent_Identity=36.9565217391304, Blast_Score=92, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24645799, Length=136, Percent_Identity=44.8529411764706, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45553335, Length=130, Percent_Identity=45.3846153846154, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21356369, Length=130, Percent_Identity=45.3846153846154, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24645801, Length=147, Percent_Identity=42.1768707482993, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221378664, Length=128, Percent_Identity=43.75, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24645804, Length=139, Percent_Identity=42.4460431654676, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI221378662, Length=135, Percent_Identity=42.2222222222222, Blast_Score=112, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 18809; Mature: 18809

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFFSRRTFILIPTMSILKIIFQPMKVLASSFSSKDEWNLSKDEWKSRLSPESYYILRE
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECC
EGTERAFSSELNNEKRKGVFHCAGCDLPLFLSDKKYDSGTGWPSFWDPIKGSVATKVDFK
CCCHHHHHHHHCCHHHCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEE
LIVPRTEYHCSRCGGHQGHVFNDGPLPTGKRYCNNGLALRFVPE
EEECCCHHHHHHCCCCCCCEECCCCCCCCHHHHCCCCEEEEECC
>Mature Secondary Structure
MNQFFSRRTFILIPTMSILKIIFQPMKVLASSFSSKDEWNLSKDEWKSRLSPESYYILRE
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEECC
EGTERAFSSELNNEKRKGVFHCAGCDLPLFLSDKKYDSGTGWPSFWDPIKGSVATKVDFK
CCCHHHHHHHHCCHHHCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEE
LIVPRTEYHCSRCGGHQGHVFNDGPLPTGKRYCNNGLALRFVPE
EEECCCHHHHHHCCCCCCCEECCCCCCCCHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]