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The map label for this gene is trpGD [H]

Identifier: 78358522

GI number: 78358522

Start: 3443433

End: 3444038

Strand: Reverse

Name: trpGD [H]

Synonym: Dde_3483

Alternate gene names: 78358522

Gene position: 3444038-3443433 (Counterclockwise)

Preceding gene: 78358523

Following gene: 78358521

Centisome position: 92.33

GC content: 62.21

Gene sequence:

>606_bases
ATGTTTTTGCTTATCGATAACTACGATTCGTTCACCTTTAATCTGGTGCAGGCCTTCAGCAAAGGCGGGCTTACTCCGCA
GGTGCGCAAAAATGACGACCCTGAACTGCCCGCGCTGGCACAAAGCGGGACACTGACCATGGTGTGCATTTCTCCCGGGC
CGGGCAATCCGGCGGGGGCAGGACTGTGCCTTGAATTTCTGGACAGGCTGCCCCGCCATGTGCCGGTACTGGGCGTGTGT
CTGGGCCATCAGGTGCTGGGCGCCTATGCCGGTGCCGCGGTGGAAGTTGGGCCGCGTATCATGCACGGCAAGGCATCCCG
CGTTGTCCATCAGGGCACGGGCCTGTTCGAGGGTGTGTGCAACCCCATGACTGTGGGCCGGTATCATTCGCTGGTTGTGC
GTGCGGAACAGTGCCCCGGCACGCTCGAAGTGCTGGCAGTCACAGACGCGGCGGTGGATGACGGGTGTGTGATGGCCATG
CGTTATCGCGACAGGCCGTGGATGGGGGTGCAGTTCCATCCCGAGTCCGTTCTGACCCCGCAGGGTGAAACCCTGTTGCA
AAACTTCTGCCGCATGGCGACTGCCTGCACGGCCGGGGCCGTGTGA

Upstream 100 bases:

>100_bases
TCGGTGCCCGAAAAAGAATGGGAAGAGTGCTGCAACAAGGCCAGAGTGGTGCGTTCGGCCATCACGGGTACGCATGGCGG
CGGATCAACGGGAGACTGCG

Downstream 100 bases:

>100_bases
ATACGAGGTAAAAAGACAATGCATACTGCAGAAATACTGGAAACACTGGCTTCGGGCGGCGTGCTGCCGCCCGAAACGGC
ACACATGGCGTTTGACAGAC

Product: anthranilate synthase, component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MFLLIDNYDSFTFNLVQAFSKGGLTPQVRKNDDPELPALAQSGTLTMVCISPGPGNPAGAGLCLEFLDRLPRHVPVLGVC
LGHQVLGAYAGAAVEVGPRIMHGKASRVVHQGTGLFEGVCNPMTVGRYHSLVVRAEQCPGTLEVLAVTDAAVDDGCVMAM
RYRDRPWMGVQFHPESVLTPQGETLLQNFCRMATACTAGAV

Sequences:

>Translated_201_residues
MFLLIDNYDSFTFNLVQAFSKGGLTPQVRKNDDPELPALAQSGTLTMVCISPGPGNPAGAGLCLEFLDRLPRHVPVLGVC
LGHQVLGAYAGAAVEVGPRIMHGKASRVVHQGTGLFEGVCNPMTVGRYHSLVVRAEQCPGTLEVLAVTDAAVDDGCVMAM
RYRDRPWMGVQFHPESVLTPQGETLLQNFCRMATACTAGAV
>Mature_201_residues
MFLLIDNYDSFTFNLVQAFSKGGLTPQVRKNDDPELPALAQSGTLTMVCISPGPGNPAGAGLCLEFLDRLPRHVPVLGVC
LGHQVLGAYAGAAVEVGPRIMHGKASRVVHQGTGLFEGVCNPMTVGRYHSLVVRAEQCPGTLEVLAVTDAAVDDGCVMAM
RYRDRPWMGVQFHPESVLTPQGETLLQNFCRMATACTAGAV

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=43.9153439153439, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1787517, Length=190, Percent_Identity=40.5263157894737, Blast_Score=131, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=35.4166666666667, Blast_Score=125, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=30.0469483568075, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21426; Mature: 21426

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLIDNYDSFTFNLVQAFSKGGLTPQVRKNDDPELPALAQSGTLTMVCISPGPGNPAGA
CEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCCHH
GLCLEFLDRLPRHVPVLGVCLGHQVLGAYAGAAVEVGPRIMHGKASRVVHQGTGLFEGVC
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHCCCCHHHHCC
NPMTVGRYHSLVVRAEQCPGTLEVLAVTDAAVDDGCVMAMRYRDRPWMGVQFHPESVLTP
CCCCCCCHHEEEEECCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCEEECCCCCCCC
QGETLLQNFCRMATACTAGAV
CCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFLLIDNYDSFTFNLVQAFSKGGLTPQVRKNDDPELPALAQSGTLTMVCISPGPGNPAGA
CEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCCHH
GLCLEFLDRLPRHVPVLGVCLGHQVLGAYAGAAVEVGPRIMHGKASRVVHQGTGLFEGVC
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHCCCCHHHHCC
NPMTVGRYHSLVVRAEQCPGTLEVLAVTDAAVDDGCVMAMRYRDRPWMGVQFHPESVLTP
CCCCCCCHHEEEEECCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCEEECCCCCCCC
QGETLLQNFCRMATACTAGAV
CCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]