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The map label for this gene is hsdM [C]

Identifier: 78358468

GI number: 78358468

Start: 3392825

End: 3394342

Strand: Reverse

Name: hsdM [C]

Synonym: Dde_3429

Alternate gene names: 78358468

Gene position: 3394342-3392825 (Counterclockwise)

Preceding gene: 78358469

Following gene: 78358467

Centisome position: 91.0

GC content: 59.68

Gene sequence:

>1518_bases
ATGAGCAGGAAGAACGGAAATAATAATCCAGTCGATCTGGATATCGGGACCCTATCCGGGCATCTCTGGGAGGCGGCCAA
TATCCTGCGTGGTCCTGTCGACGCGGCCGATTTCAAGACCTACATCTTTCCGCTGCTGTTCTTCAAGCGGCTCTCCGACG
TCTATGACGAGGAGTATGCCGTGGCCCTGGAAGAGTCCGACGGCGATGTGGAGTTTGCCCAGTTCCCCGAGAACCACCGT
TTCCAGGTTCCGGAGGGCTGCCACTGGAAAGATGTCCGGGCCAAGAGCGCCAATATCGGCCATGCGCTCCAGAAGGCCAT
GCGCTGCATCGAGCAAGCCAACCCGGACACCCTGCACGGCATCTTCGGCGATGCCCAGTGGACCAACAAAGACCGCCTTT
CGGACGCGCTGCTCAAGGACCTGATCGAACACTTCTCGTCGCTCAACCTGGGCAATAAGCACTGCAAGGCGGACATTCTC
GGCCAAGCCTATGAATACCTGATCAAGAAATTTGCCGACCTGACCAACAAGAAGGCCGGTGAATTCTATACCCCACGCTC
CGTGGTCGCGCTGATGGTTCGCATCCTTGCGCCCAAGGCCGGGGAAACCATCTACGACCCGGCCTGTGGGACCGGCGGCA
TGCTCCTCGAGGCGCTGCACCATGTCAAAGAACATGGCGGCGACGAGAACCTCATGCTGGGCAAGCTCTACGGCCAGGAA
AAGAACCTGACCACATCCTCCATCGCCCGGATGAACCTCTTTCTCCACGGCGCGGAAGATTTCCATATCGAACGCAGCGA
CACACTGCGATTGCCCGCCTTTTATTCAGGCGACAGCCTCGCCACCTTTGACTGCGTCATCGCCAATCCTCCCTTCTCCC
TGGAAAAGTGGGGGGACGACGTCTGGATCAACGACCCCTACGGCCGCAACTTTGCCGGACTGCCGCCAGCCAAATCCGGC
GACTTCGCCTGGGTTCAGCACATGATCAAGTCCATGGCTCGCAAGACCGGCCGCATGGCCGTGGTGCTCCCCCATGGCGT
GCTGTTCCGCATGTCCAAGGAAGGCGAGATCCGGCGCAAGCTGCTGGAGATGGATATGCTCGAAGCGGTGATCGGCCTCG
GCCAGAACATTTTCTACGGCACCAGTCTCGCGCCCTGCGTCCTGGTCTTCCGCGACAGCAAACCCAAGGCGCACCGCCAG
AAGGTGCTGTTCATCGACGCCTCCAAGGAGTTCAAAACCGGCCGTGCCCAGAACGAGCTGCTGCCGGAACACGTGGACAA
CATCCATCGCTGGTACGAGGGCTATCAGGATGTGGAAGGGATCTGCCGGGTGGTCACGCTCGACGAGATCCGCGAGAACG
ATTTCAACCTGAACATCCCCCGCTACGTGGAGCCGGTGATCGAGGAAGAATCCATGACCATCGATCAGGCCATCGTCAAC
CTCAAGGAATCGTTGCAGGCGGCGTATGCGGCCGAGGATCGGTTGAAGGGGCTGCTGCTCCGGGAGGGTCTGCTGTGA

Upstream 100 bases:

>100_bases
CCCATCGCATGGGCCGTCTTTGGAAGTTCAAGAAAGATGAGGTCGACGAGTGGGTGAAGGCTGGCGGCGCGGCGGACAAG
AGCAGACAGGATCAAGCTGA

Downstream 100 bases:

>100_bases
AAGTCTACCAGTACAAATCACCCATCGGCCGCTTTCTCATCAAACCGCAAGCCAACGGTCGCTGGGGGCTTTGGTTCAAG
GATGACCTGCTCGGCTCTTA

Product: type I restriction-modification system, M subunit

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSRKNGNNNPVDLDIGTLSGHLWEAANILRGPVDAADFKTYIFPLLFFKRLSDVYDEEYAVALEESDGDVEFAQFPENHR
FQVPEGCHWKDVRAKSANIGHALQKAMRCIEQANPDTLHGIFGDAQWTNKDRLSDALLKDLIEHFSSLNLGNKHCKADIL
GQAYEYLIKKFADLTNKKAGEFYTPRSVVALMVRILAPKAGETIYDPACGTGGMLLEALHHVKEHGGDENLMLGKLYGQE
KNLTTSSIARMNLFLHGAEDFHIERSDTLRLPAFYSGDSLATFDCVIANPPFSLEKWGDDVWINDPYGRNFAGLPPAKSG
DFAWVQHMIKSMARKTGRMAVVLPHGVLFRMSKEGEIRRKLLEMDMLEAVIGLGQNIFYGTSLAPCVLVFRDSKPKAHRQ
KVLFIDASKEFKTGRAQNELLPEHVDNIHRWYEGYQDVEGICRVVTLDEIRENDFNLNIPRYVEPVIEEESMTIDQAIVN
LKESLQAAYAAEDRLKGLLLREGLL

Sequences:

>Translated_505_residues
MSRKNGNNNPVDLDIGTLSGHLWEAANILRGPVDAADFKTYIFPLLFFKRLSDVYDEEYAVALEESDGDVEFAQFPENHR
FQVPEGCHWKDVRAKSANIGHALQKAMRCIEQANPDTLHGIFGDAQWTNKDRLSDALLKDLIEHFSSLNLGNKHCKADIL
GQAYEYLIKKFADLTNKKAGEFYTPRSVVALMVRILAPKAGETIYDPACGTGGMLLEALHHVKEHGGDENLMLGKLYGQE
KNLTTSSIARMNLFLHGAEDFHIERSDTLRLPAFYSGDSLATFDCVIANPPFSLEKWGDDVWINDPYGRNFAGLPPAKSG
DFAWVQHMIKSMARKTGRMAVVLPHGVLFRMSKEGEIRRKLLEMDMLEAVIGLGQNIFYGTSLAPCVLVFRDSKPKAHRQ
KVLFIDASKEFKTGRAQNELLPEHVDNIHRWYEGYQDVEGICRVVTLDEIRENDFNLNIPRYVEPVIEEESMTIDQAIVN
LKESLQAAYAAEDRLKGLLLREGLL
>Mature_504_residues
SRKNGNNNPVDLDIGTLSGHLWEAANILRGPVDAADFKTYIFPLLFFKRLSDVYDEEYAVALEESDGDVEFAQFPENHRF
QVPEGCHWKDVRAKSANIGHALQKAMRCIEQANPDTLHGIFGDAQWTNKDRLSDALLKDLIEHFSSLNLGNKHCKADILG
QAYEYLIKKFADLTNKKAGEFYTPRSVVALMVRILAPKAGETIYDPACGTGGMLLEALHHVKEHGGDENLMLGKLYGQEK
NLTTSSIARMNLFLHGAEDFHIERSDTLRLPAFYSGDSLATFDCVIANPPFSLEKWGDDVWINDPYGRNFAGLPPAKSGD
FAWVQHMIKSMARKTGRMAVVLPHGVLFRMSKEGEIRRKLLEMDMLEAVIGLGQNIFYGTSLAPCVLVFRDSKPKAHRQK
VLFIDASKEFKTGRAQNELLPEHVDNIHRWYEGYQDVEGICRVVTLDEIRENDFNLNIPRYVEPVIEEESMTIDQAIVNL
KESLQAAYAAEDRLKGLLLREGLL

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=391, Percent_Identity=27.1099744245524, Blast_Score=112, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 56929; Mature: 56797

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKNGNNNPVDLDIGTLSGHLWEAANILRGPVDAADFKTYIFPLLFFKRLSDVYDEEYA
CCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
VALEESDGDVEFAQFPENHRFQVPEGCHWKDVRAKSANIGHALQKAMRCIEQANPDTLHG
EEEECCCCCEEHHHCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
IFGDAQWTNKDRLSDALLKDLIEHFSSLNLGNKHCKADILGQAYEYLIKKFADLTNKKAG
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EFYTPRSVVALMVRILAPKAGETIYDPACGTGGMLLEALHHVKEHGGDENLMLGKLYGQE
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
KNLTTSSIARMNLFLHGAEDFHIERSDTLRLPAFYSGDSLATFDCVIANPPFSLEKWGDD
CCCCHHHHHHHHHEEECCCCEEECCCCCEECCEEECCCCEEEEEEEECCCCCCHHHCCCC
VWINDPYGRNFAGLPPAKSGDFAWVQHMIKSMARKTGRMAVVLPHGVLFRMSKEGEIRRK
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCHHHHHH
LLEMDMLEAVIGLGQNIFYGTSLAPCVLVFRDSKPKAHRQKVLFIDASKEFKTGRAQNEL
HHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCCCCEEEEEECCCHHCCCCCHHHC
LPEHVDNIHRWYEGYQDVEGICRVVTLDEIRENDFNLNIPRYVEPVIEEESMTIDQAIVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LKESLQAAYAAEDRLKGLLLREGLL
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRKNGNNNPVDLDIGTLSGHLWEAANILRGPVDAADFKTYIFPLLFFKRLSDVYDEEYA
CCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
VALEESDGDVEFAQFPENHRFQVPEGCHWKDVRAKSANIGHALQKAMRCIEQANPDTLHG
EEEECCCCCEEHHHCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
IFGDAQWTNKDRLSDALLKDLIEHFSSLNLGNKHCKADILGQAYEYLIKKFADLTNKKAG
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EFYTPRSVVALMVRILAPKAGETIYDPACGTGGMLLEALHHVKEHGGDENLMLGKLYGQE
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
KNLTTSSIARMNLFLHGAEDFHIERSDTLRLPAFYSGDSLATFDCVIANPPFSLEKWGDD
CCCCHHHHHHHHHEEECCCCEEECCCCCEECCEEECCCCEEEEEEEECCCCCCHHHCCCC
VWINDPYGRNFAGLPPAKSGDFAWVQHMIKSMARKTGRMAVVLPHGVLFRMSKEGEIRRK
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCHHHHHH
LLEMDMLEAVIGLGQNIFYGTSLAPCVLVFRDSKPKAHRQKVLFIDASKEFKTGRAQNEL
HHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCCCCEEEEEECCCHHCCCCCHHHC
LPEHVDNIHRWYEGYQDVEGICRVVTLDEIRENDFNLNIPRYVEPVIEEESMTIDQAIVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LKESLQAAYAAEDRLKGLLLREGLL
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]