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The map label for this gene is nisX1 [H]

Identifier: 78358401

GI number: 78358401

Start: 3333815

End: 3334552

Strand: Reverse

Name: nisX1 [H]

Synonym: Dde_3361

Alternate gene names: 78358401

Gene position: 3334552-3333815 (Counterclockwise)

Preceding gene: 78358402

Following gene: 304570593

Centisome position: 89.39

GC content: 57.32

Gene sequence:

>738_bases
ATGCAGCGCATCGACGAGTTGTTCATGGAGTTGCCGTTCTTCGGCTCCCGGCAAATGCGCAACATCCTGCGAGATGAGGG
ACATTTCGTCGGGCGTAATCGTGTGCGTCGGCTCATGCGCAAGATGGGGCTGATGGCGGTCTACCAAAAGCCGCGAACCA
GCCAGCCACACCCGCAGCACAAGACGTATCCGTATCTGTTGCGGGGCAAGGCGATCACGAAGCCGAATCAGGTGTGGTGC
GCCGACATCACGTACATTCCGATGCGGCGTGGCTTCCTGTACCTCGTGGCGATCATGGATTGGCATAGTCGAGCCGTGCT
GTCATGGCGCTTGTCGAACACGATGGACGCTGACTTCTGCGTGGCAGCCCTGGAAGAGGCCATGAACCGATACGGCGTGC
CGGATATCTTCAACACCGACCAAGGCTCGCAATTCACGAGCTACGAGTTCACACGGACGCTCAGACAGGCAGGAGCCAAG
ATCTCAATGGATGGTCGAGGCCGCTGGATGGACAACGTTATGATCGAACGCCTCTGGCGTTCGTTGAAGTATGAATGCGT
GTATTTGCGGGAAATTGAGACAGGAAGCGAGCTTCGTCGCACCCTGGCCTGGTGGTTTGAGTTCTACAACAATCGCCGTC
CGCACAAGACCTTTGACGGCAGGAAGCCGATGGAGATATATCAACAGTTCAAGCCAGAGGGGGTACCCCCTCTGGCTTGC
CCCAGAAAGGCGGCATAG

Upstream 100 bases:

>100_bases
TCCTGCGCTCAGTGTTCGGCGGCAGTGCGAAGCCCTGAAGCTGCACCGCTCAACGTATTACTATCAGCCGATCGGCGAGT
CCGAGTACAATCTGACGTTG

Downstream 100 bases:

>100_bases
CCAACGAAACTGTCCACCTTAGTTTTGCCGCTGACTGGTCCAAAGAAGTGAACCCACTTCTATGCATCCGTCGAACTTAT
GTTTACGTATCTAAACAAAA

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MQRIDELFMELPFFGSRQMRNILRDEGHFVGRNRVRRLMRKMGLMAVYQKPRTSQPHPQHKTYPYLLRGKAITKPNQVWC
ADITYIPMRRGFLYLVAIMDWHSRAVLSWRLSNTMDADFCVAALEEAMNRYGVPDIFNTDQGSQFTSYEFTRTLRQAGAK
ISMDGRGRWMDNVMIERLWRSLKYECVYLREIETGSELRRTLAWWFEFYNNRRPHKTFDGRKPMEIYQQFKPEGVPPLAC
PRKAA

Sequences:

>Translated_245_residues
MQRIDELFMELPFFGSRQMRNILRDEGHFVGRNRVRRLMRKMGLMAVYQKPRTSQPHPQHKTYPYLLRGKAITKPNQVWC
ADITYIPMRRGFLYLVAIMDWHSRAVLSWRLSNTMDADFCVAALEEAMNRYGVPDIFNTDQGSQFTSYEFTRTLRQAGAK
ISMDGRGRWMDNVMIERLWRSLKYECVYLREIETGSELRRTLAWWFEFYNNRRPHKTFDGRKPMEIYQQFKPEGVPPLAC
PRKAA
>Mature_245_residues
MQRIDELFMELPFFGSRQMRNILRDEGHFVGRNRVRRLMRKMGLMAVYQKPRTSQPHPQHKTYPYLLRGKAITKPNQVWC
ADITYIPMRRGFLYLVAIMDWHSRAVLSWRLSNTMDADFCVAALEEAMNRYGVPDIFNTDQGSQFTSYEFTRTLRQAGAK
ISMDGRGRWMDNVMIERLWRSLKYECVYLREIETGSELRRTLAWWFEFYNNRRPHKTFDGRKPMEIYQQFKPEGVPPLAC
PRKAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=183, Percent_Identity=31.6939890710383, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1789981, Length=233, Percent_Identity=29.6137339055794, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788405, Length=219, Percent_Identity=29.6803652968037, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787263, Length=219, Percent_Identity=29.6803652968037, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1786753, Length=219, Percent_Identity=29.6803652968037, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1786570, Length=219, Percent_Identity=29.6803652968037, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1786490, Length=219, Percent_Identity=29.6803652968037, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1786462, Length=235, Percent_Identity=25.9574468085106, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 29208; Mature: 29208

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIDELFMELPFFGSRQMRNILRDEGHFVGRNRVRRLMRKMGLMAVYQKPRTSQPHPQH
CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KTYPYLLRGKAITKPNQVWCADITYIPMRRGFLYLVAIMDWHSRAVLSWRLSNTMDADFC
CCCCEEEECCEECCCCCEEEECEEEHHHHCCHHHHHHHHHHCCHHEEEEECCCCCCHHHH
VAALEEAMNRYGVPDIFNTDQGSQFTSYEFTRTLRQAGAKISMDGRGRWMDNVMIERLWR
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHH
SLKYECVYLREIETGSELRRTLAWWFEFYNNRRPHKTFDGRKPMEIYQQFKPEGVPPLAC
HHCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
PRKAA
CCCCC
>Mature Secondary Structure
MQRIDELFMELPFFGSRQMRNILRDEGHFVGRNRVRRLMRKMGLMAVYQKPRTSQPHPQH
CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KTYPYLLRGKAITKPNQVWCADITYIPMRRGFLYLVAIMDWHSRAVLSWRLSNTMDADFC
CCCCEEEECCEECCCCCEEEECEEEHHHHCCHHHHHHHHHHCCHHEEEEECCCCCCHHHH
VAALEEAMNRYGVPDIFNTDQGSQFTSYEFTRTLRQAGAKISMDGRGRWMDNVMIERLWR
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHH
SLKYECVYLREIETGSELRRTLAWWFEFYNNRRPHKTFDGRKPMEIYQQFKPEGVPPLAC
HHCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
PRKAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]