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The map label for this gene is aroK

Identifier: 78357651

GI number: 78357651

Start: 2627351

End: 2627899

Strand: Direct

Name: aroK

Synonym: Dde_2609

Alternate gene names: 78357651

Gene position: 2627351-2627899 (Clockwise)

Preceding gene: 78357650

Following gene: 78357652

Centisome position: 70.43

GC content: 57.56

Gene sequence:

>549_bases
ATGACGCAGAATACATATATTCCCCGTCCCGAACCATCAGAACAGGACGGGTGCATTATCCTCATCGGCATGGCCGGTTG
CGGCAAAAGCACCATAGGCGCGGCGCTGGCCCGGCACATGAACTGGGCACACATGGACAGTGATCATCTGATAGAAGCCC
ATTACGGCACCACCCTGCAGCAGGTTGCCGACAGTATGGACAAAGAGACCTTTCTGGACGTGGAAAGCGCCGTCTGCCGG
CGTATAAACGTACGGCGTACCGTCATATCGACCGGCGGCAGCGTGGTGTACAGAGCCGCGGGAATGGCACATCTGAAGTC
ACTGGGGCCTGTGGTGTACCTGCAGGTTGATCTGCCGGTGATACTGGAACGCATAAGCCGCAACCCTGACCGGGGTCTGG
CCATCGCCCCCGGGCAGACTGTTGAAGACCTGTACAACGAACGCATCGCCCTGTATGAAACCTATGCCGATATAACCGTT
CCGTGCACCACTGCCGGTGTACAGGAATGTGTCACGGCCATCAGCAGACTGCTGACGGAGTTGAGATGA

Upstream 100 bases:

>100_bases
CGCACAGTCCTGCAGCGTCCGCGGTTGACACCGGCCCGCCGCCGCAGCAAACTGCCGCAGACAACACCGCCTTCTTTCAC
AGCAAGGAAACCAGACCCAT

Downstream 100 bases:

>100_bases
AGCACAGCAGAACAGCCGCAGCAAAGCGGAAAACAGGTGTTTTTGCGCGCCTTGCAGACCTGTACACCCGCATGGAACAG
GAATACAGCGACAAAGCCCG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MTQNTYIPRPEPSEQDGCIILIGMAGCGKSTIGAALARHMNWAHMDSDHLIEAHYGTTLQQVADSMDKETFLDVESAVCR
RINVRRTVISTGGSVVYRAAGMAHLKSLGPVVYLQVDLPVILERISRNPDRGLAIAPGQTVEDLYNERIALYETYADITV
PCTTAGVQECVTAISRLLTELR

Sequences:

>Translated_182_residues
MTQNTYIPRPEPSEQDGCIILIGMAGCGKSTIGAALARHMNWAHMDSDHLIEAHYGTTLQQVADSMDKETFLDVESAVCR
RINVRRTVISTGGSVVYRAAGMAHLKSLGPVVYLQVDLPVILERISRNPDRGLAIAPGQTVEDLYNERIALYETYADITV
PCTTAGVQECVTAISRLLTELR
>Mature_181_residues
TQNTYIPRPEPSEQDGCIILIGMAGCGKSTIGAALARHMNWAHMDSDHLIEAHYGTTLQQVADSMDKETFLDVESAVCRR
INVRRTVISTGGSVVYRAAGMAHLKSLGPVVYLQVDLPVILERISRNPDRGLAIAPGQTVEDLYNERIALYETYADITVP
CTTAGVQECVTAISRLLTELR

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=146, Percent_Identity=36.986301369863, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786587, Length=155, Percent_Identity=28.3870967741935, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19932; Mature: 19801

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNTYIPRPEPSEQDGCIILIGMAGCGKSTIGAALARHMNWAHMDSDHLIEAHYGTTLQ
CCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHCCCCCCEEEHHCCCHHH
QVADSMDKETFLDVESAVCRRINVRRTVISTGGSVVYRAAGMAHLKSLGPVVYLQVDLPV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECHHH
ILERISRNPDRGLAIAPGQTVEDLYNERIALYETYADITVPCTTAGVQECVTAISRLLTE
HHHHHHCCCCCCEEECCCCHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHH
LR
CC
>Mature Secondary Structure 
TQNTYIPRPEPSEQDGCIILIGMAGCGKSTIGAALARHMNWAHMDSDHLIEAHYGTTLQ
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHCCCCCCEEEHHCCCHHH
QVADSMDKETFLDVESAVCRRINVRRTVISTGGSVVYRAAGMAHLKSLGPVVYLQVDLPV
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECHHH
ILERISRNPDRGLAIAPGQTVEDLYNERIALYETYADITVPCTTAGVQECVTAISRLLTE
HHHHHHCCCCCCEEECCCCHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHH
LR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA