Click here to switch to the map view.

The map label for this gene is yqhH [H]

Identifier: 78355826

GI number: 78355826

Start: 799703

End: 801700

Strand: Direct

Name: yqhH [H]

Synonym: Dde_0779

Alternate gene names: 78355826

Gene position: 799703-801700 (Clockwise)

Preceding gene: 78355824

Following gene: 78355827

Centisome position: 21.44

GC content: 47.3

Gene sequence:

>1998_bases
ATGACTACACCGTACCATGCCAAATACTTTGCACACGACTTGACGATCCAGAAGCCTTTAGATGGAGTCGAAAGGCTTTC
TCGTTCTCTTTTTGACGCATGTGTAGACCTTAATCCTCATCAAATTGATGCTGCTCTGTTTGCCTTCAGATCACCTCTTT
CAAAAGGTGTCATCTTAGCTGATGAAGTTGGTCTGGGAAAAACAATCGAGGCAGGATTGCTTCTTTGTCAGTATTGGGCA
GAACGGAAAAGAAACATTATTATAGTTTGCCCTGCTTCTGTAGTCATTGACGCACGCGCTTATAGATTAGAGAAAAAGAA
CGGCAACATTACTCCGTTTGATCAAAATTGCGTCATAATCACTTCTCTTCACTATGCCGCGCGCATGAAAGAAGAACTGC
GCCTTACAAAATGGGACTTGGTTGTCATTGATGAAGCCCATAAGCTGAGAAATGCCTACCGACCAAGCAACAAGATGGGA
CAAGGGCTTCGATGGGCTTTTGAGGATTGTTTCAAAGTCCTTTTGACAGCTACCCCTCTCCAGAACTCTCTTCTTGAACT
CTACGGACTTTCGACGTTCATTGACGACTATATGTTTGGAGACATCAGCTCCTTTCGTTCCCAGTTTGTGAATAGCGGTG
GTGATTTACCCGGTCTACGAGACAGAATGGCTCCTTTCTGCAAAAGAACTCTTCGCAAAGATGTTCTCGAATATATTCAA
TACACTGAAAGAAAACCCATCGCCTTCAGATTCCGATCCACAGACGAAGAGCAGCGTCTATATGATGCTGTCACCGAATT
TCTCAAACGAGAGGAAACATATTCTTTCCCAAGCCAGCAACGCCAACTGATCACCCTCATAATGCGTAAGCTGCTCGCAT
CCTCTTCTCAGGCTTTGCTTGGAACCCTTCAGACAATGCGAAAACGCCTTCTGGACCTGAAAGAAGGAATTGAGGCTGAA
CGCAGCCTTGCAGAAGAACTCATCGACCTGGAGGAAATTGAGGACGATCTTCTCGAAGAAGATGAGCTATACGATCCTTT
ACTCAGTGAAGATGCCGAGGCCCCGGACGATGGCAAACTCGACCTTGAAAAGCTTGCGGAAGAAATTACTGAATTGGACA
AGTACATTACCTGGGCAGAAAGCATCCGGGTTGACTCAAAGTCCAAGACATTGCTCAAGGGGCTTGAGACAGGATTCGCT
GAGATGCAGAAGATGGGAGCAAGGCGTAGAGCCCTCATCTTCACTGAATCTCGAAGAACCCAGGATTACCTCAAGAGCTT
CCTTGAAGCGAATGGTTACGCCAACAAAGTCATTGCGTTCAACGGGACCAATACTGCCCAAGAGACACGGGCGATTTACG
ATTCTTGGCTCGACAAGAACCAGGGCACAGGACGAATCAGTGGTTCAAGGCCCATTGATGTCAGAACCGCTCTTGTCGAA
CACTTTCGAGACAACGCGCAAATCATGATCGCTACAGAAGCGGCGGCGGAAGGTGTAAACCTTCAGTTCTGCTCCTTGAT
CGTCAACTATGACCTTCCCTGGAACCCACAAAGGATCGAACAGCGTATCGGCAGGTGCCATCGCTATGGACAGAAGCACG
ATGTTGTCGTGGTGAACTTTTTGAACGAACGAAACGCAGCCGACCAGCGCGTATACGAGTTATTGGAGCACAAGTTCAAT
CTCTTCAACGGAGTGTTTGGAGCATCGGACGCGGTTCTCGGCTCGATTGAATCAGGTGTGGATTTCGAAAAAAGGATTCT
TGGGATATATCAATCCTGCCGAACTACGGAAGAGATTGAAAAAGCCTTTGCGGCTCTCCAGGCAGAGCTTGAAGAGCAGA
TCAATACGAAAATGGAGAAGACCAAGCAGCTCCTTCTCGACAACTTTGACGAGGATGTTCATACCCGCCTTAAAGTCCAG
CTGGATGACGCGCATAGGCAAAACGGGATGCCCAGGATGCTGGGCAGAAAAATTAAGGGCTACATTATGGAGGTATGA

Upstream 100 bases:

>100_bases
CCACATATGTTGGGCTCCCCCCTACAACAGATAAGCCTAATAAGGCTTCACGTTTTTGGGCGAACACGATACAGAAAATG
AAAAAATATTTTCAAGAACT

Downstream 100 bases:

>100_bases
TCGGTAGTTATGACTTTACCAATGCCAGAGAAGTTTTGGGACATCAGAATCCATAAGGTAGACATTCATCCAGGTGTGAC
CGGATTATGCGTCGGCTATG

Product: DEAD/DEAH box helicase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MTTPYHAKYFAHDLTIQKPLDGVERLSRSLFDACVDLNPHQIDAALFAFRSPLSKGVILADEVGLGKTIEAGLLLCQYWA
ERKRNIIIVCPASVVIDARAYRLEKKNGNITPFDQNCVIITSLHYAARMKEELRLTKWDLVVIDEAHKLRNAYRPSNKMG
QGLRWAFEDCFKVLLTATPLQNSLLELYGLSTFIDDYMFGDISSFRSQFVNSGGDLPGLRDRMAPFCKRTLRKDVLEYIQ
YTERKPIAFRFRSTDEEQRLYDAVTEFLKREETYSFPSQQRQLITLIMRKLLASSSQALLGTLQTMRKRLLDLKEGIEAE
RSLAEELIDLEEIEDDLLEEDELYDPLLSEDAEAPDDGKLDLEKLAEEITELDKYITWAESIRVDSKSKTLLKGLETGFA
EMQKMGARRRALIFTESRRTQDYLKSFLEANGYANKVIAFNGTNTAQETRAIYDSWLDKNQGTGRISGSRPIDVRTALVE
HFRDNAQIMIATEAAAEGVNLQFCSLIVNYDLPWNPQRIEQRIGRCHRYGQKHDVVVVNFLNERNAADQRVYELLEHKFN
LFNGVFGASDAVLGSIESGVDFEKRILGIYQSCRTTEEIEKAFAALQAELEEQINTKMEKTKQLLLDNFDEDVHTRLKVQ
LDDAHRQNGMPRMLGRKIKGYIMEV

Sequences:

>Translated_665_residues
MTTPYHAKYFAHDLTIQKPLDGVERLSRSLFDACVDLNPHQIDAALFAFRSPLSKGVILADEVGLGKTIEAGLLLCQYWA
ERKRNIIIVCPASVVIDARAYRLEKKNGNITPFDQNCVIITSLHYAARMKEELRLTKWDLVVIDEAHKLRNAYRPSNKMG
QGLRWAFEDCFKVLLTATPLQNSLLELYGLSTFIDDYMFGDISSFRSQFVNSGGDLPGLRDRMAPFCKRTLRKDVLEYIQ
YTERKPIAFRFRSTDEEQRLYDAVTEFLKREETYSFPSQQRQLITLIMRKLLASSSQALLGTLQTMRKRLLDLKEGIEAE
RSLAEELIDLEEIEDDLLEEDELYDPLLSEDAEAPDDGKLDLEKLAEEITELDKYITWAESIRVDSKSKTLLKGLETGFA
EMQKMGARRRALIFTESRRTQDYLKSFLEANGYANKVIAFNGTNTAQETRAIYDSWLDKNQGTGRISGSRPIDVRTALVE
HFRDNAQIMIATEAAAEGVNLQFCSLIVNYDLPWNPQRIEQRIGRCHRYGQKHDVVVVNFLNERNAADQRVYELLEHKFN
LFNGVFGASDAVLGSIESGVDFEKRILGIYQSCRTTEEIEKAFAALQAELEEQINTKMEKTKQLLLDNFDEDVHTRLKVQ
LDDAHRQNGMPRMLGRKIKGYIMEV
>Mature_664_residues
TTPYHAKYFAHDLTIQKPLDGVERLSRSLFDACVDLNPHQIDAALFAFRSPLSKGVILADEVGLGKTIEAGLLLCQYWAE
RKRNIIIVCPASVVIDARAYRLEKKNGNITPFDQNCVIITSLHYAARMKEELRLTKWDLVVIDEAHKLRNAYRPSNKMGQ
GLRWAFEDCFKVLLTATPLQNSLLELYGLSTFIDDYMFGDISSFRSQFVNSGGDLPGLRDRMAPFCKRTLRKDVLEYIQY
TERKPIAFRFRSTDEEQRLYDAVTEFLKREETYSFPSQQRQLITLIMRKLLASSSQALLGTLQTMRKRLLDLKEGIEAER
SLAEELIDLEEIEDDLLEEDELYDPLLSEDAEAPDDGKLDLEKLAEEITELDKYITWAESIRVDSKSKTLLKGLETGFAE
MQKMGARRRALIFTESRRTQDYLKSFLEANGYANKVIAFNGTNTAQETRAIYDSWLDKNQGTGRISGSRPIDVRTALVEH
FRDNAQIMIATEAAAEGVNLQFCSLIVNYDLPWNPQRIEQRIGRCHRYGQKHDVVVVNFLNERNAADQRVYELLEHKFNL
FNGVFGASDAVLGSIESGVDFEKRILGIYQSCRTTEEIEKAFAALQAELEEQINTKMEKTKQLLLDNFDEDVHTRLKVQL
DDAHRQNGMPRMLGRKIKGYIMEV

Specific function: Transcription Regulator That Activates Transcription By Stimulating RNA Polymerase (Rnap) Recycling In Case Of Stress Conditions Such As Supercoiled DNA Or High Salt Concentrations. Probably Acts By Releasing The Rnap, When It Is Trapped Or Immobilized On

COG id: COG0553

COG function: function code KL; Superfamily II DNA/RNA helicases, SNF2 family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4557565, Length=539, Percent_Identity=23.5621521335807, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI48255898, Length=214, Percent_Identity=29.4392523364486, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI48255900, Length=214, Percent_Identity=29.4392523364486, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI192807316, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI192807314, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI192807318, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI192807320, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI192807312, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI21071056, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI192807323, Length=215, Percent_Identity=28.8372093023256, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI6912622, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI146219843, Length=242, Percent_Identity=27.6859504132231, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI51599156, Length=244, Percent_Identity=26.2295081967213, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI24308089, Length=246, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786245, Length=193, Percent_Identity=34.1968911917098, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551114, Length=560, Percent_Identity=23.5714285714286, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25144179, Length=206, Percent_Identity=30.0970873786408, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71995707, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324864, Length=218, Percent_Identity=29.8165137614679, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324879, Length=204, Percent_Identity=29.9019607843137, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319722, Length=226, Percent_Identity=27.8761061946903, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666729, Length=575, Percent_Identity=22.7826086956522, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI85724914, Length=547, Percent_Identity=23.7659963436929, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24583161, Length=547, Percent_Identity=23.5831809872029, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24664914, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17985967, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24664907, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574896, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24656966, Length=254, Percent_Identity=28.740157480315, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24656962, Length=254, Percent_Identity=28.740157480315, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573600, Length=254, Percent_Identity=28.740157480315, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI85724912, Length=281, Percent_Identity=28.4697508896797, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000330 [H]

Pfam domain/function: PF00271 Helicase_C; PF00176 SNF2_N [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 76262; Mature: 76131

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPYHAKYFAHDLTIQKPLDGVERLSRSLFDACVDLNPHQIDAALFAFRSPLSKGVILA
CCCCCCHHHHHHCCCHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEE
DEVGLGKTIEAGLLLCQYWAERKRNIIIVCPASVVIDARAYRLEKKNGNITPFDQNCVII
ECCCCCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHEECCCCCCCCCCCCEEEE
TSLHYAARMKEELRLTKWDLVVIDEAHKLRNAYRPSNKMGQGLRWAFEDCFKVLLTATPL
EEHHHHHHHHHHHHHHHEEEEEECCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCH
QNSLLELYGLSTFIDDYMFGDISSFRSQFVNSGGDLPGLRDRMAPFCKRTLRKDVLEYIQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YTERKPIAFRFRSTDEEQRLYDAVTEFLKREETYSFPSQQRQLITLIMRKLLASSSQALL
HHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHH
GTLQTMRKRLLDLKEGIEAERSLAEELIDLEEIEDDLLEEDELYDPLLSEDAEAPDDGKL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCCCCCCCCCCC
DLEKLAEEITELDKYITWAESIRVDSKSKTLLKGLETGFAEMQKMGARRRALIFTESRRT
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
QDYLKSFLEANGYANKVIAFNGTNTAQETRAIYDSWLDKNQGTGRISGSRPIDVRTALVE
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
HFRDNAQIMIATEAAAEGVNLQFCSLIVNYDLPWNPQRIEQRIGRCHRYGQKHDVVVVNF
HHCCCCEEEEEEHHHCCCCCCEEEHEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
LNERNAADQRVYELLEHKFNLFNGVFGASDAVLGSIESGVDFEKRILGIYQSCRTTEEIE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHH
KAFAALQAELEEQINTKMEKTKQLLLDNFDEDVHTRLKVQLDDAHRQNGMPRMLGRKIKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEECHHHHHCCCHHHHHHHHHH
YIMEV
HHCCC
>Mature Secondary Structure 
TTPYHAKYFAHDLTIQKPLDGVERLSRSLFDACVDLNPHQIDAALFAFRSPLSKGVILA
CCCCCHHHHHHCCCHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEE
DEVGLGKTIEAGLLLCQYWAERKRNIIIVCPASVVIDARAYRLEKKNGNITPFDQNCVII
ECCCCCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHEECCCCCCCCCCCCEEEE
TSLHYAARMKEELRLTKWDLVVIDEAHKLRNAYRPSNKMGQGLRWAFEDCFKVLLTATPL
EEHHHHHHHHHHHHHHHEEEEEECCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCH
QNSLLELYGLSTFIDDYMFGDISSFRSQFVNSGGDLPGLRDRMAPFCKRTLRKDVLEYIQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YTERKPIAFRFRSTDEEQRLYDAVTEFLKREETYSFPSQQRQLITLIMRKLLASSSQALL
HHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHH
GTLQTMRKRLLDLKEGIEAERSLAEELIDLEEIEDDLLEEDELYDPLLSEDAEAPDDGKL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCCCCCCCCCCC
DLEKLAEEITELDKYITWAESIRVDSKSKTLLKGLETGFAEMQKMGARRRALIFTESRRT
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
QDYLKSFLEANGYANKVIAFNGTNTAQETRAIYDSWLDKNQGTGRISGSRPIDVRTALVE
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
HFRDNAQIMIATEAAAEGVNLQFCSLIVNYDLPWNPQRIEQRIGRCHRYGQKHDVVVVNF
HHCCCCEEEEEEHHHCCCCCCEEEHEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
LNERNAADQRVYELLEHKFNLFNGVFGASDAVLGSIESGVDFEKRILGIYQSCRTTEEIE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHH
KAFAALQAELEEQINTKMEKTKQLLLDNFDEDVHTRLKVQLDDAHRQNGMPRMLGRKIKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEECHHHHHCCCHHHHHHHHHH
YIMEV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]