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The map label for this gene is rsbU [H]

Identifier: 78355819

GI number: 78355819

Start: 794704

End: 796212

Strand: Direct

Name: rsbU [H]

Synonym: Dde_0772

Alternate gene names: 78355819

Gene position: 794704-796212 (Clockwise)

Preceding gene: 78355818

Following gene: 78355823

Centisome position: 21.3

GC content: 60.97

Gene sequence:

>1509_bases
ATGAGCGCGCTTCCGGTCTGGAAGCTGGCACTGGTCATCGCCGCCGTTACCGGCGCGGCACTGCTGCTGCGCCGGCTGGT
GGTGCTGCCGCATGTGCTCTCGCTGCCGGTGGCCCGGCGGGCGGAGCGTCTGGGGCAGTGCGACTTTGTGCTGTTTGCAG
GCGCGGGAGTGCTGATGGCGCTGGCAAACACCGTGATCAACGGCGTGCCGCTGCTTTCCAGCGGGGGCAAGCTGGTTCTG
GGCATGGTGGCGCTGGGCGTTTTTGTTTCCATCGACCTTGCCCTTGAATGCGAGCGCCGGAGCATACGTCTGGCCGGCAT
AACCGAGCCGGAAAGGCTGCCTCCCCGGCGGTTTTCTTCTCTCACGCGTAAATTTTTTGCTGTGGCTACCGTGGTGACGG
TGCTGTTTTCGCTTATTGTCATTCTGGCGGTGTTCCGTGATCTGTGGTGGTTTACAGAGGCAGGACTCAACGAAGGTTCA
CTGCGGTTTGTAAAGCGCAGCATTCTGATAGATCTTTCATTCATCATGGGCATGCTGCTGGTGCTGGTGATAAATCTTGC
TTTGTCCTATTCCCGTAACCTGCGTCTGCTTTTTGATAATCAGACGCAGGTGCTGGTGCGGGTGAGCAACGGAGACATGA
GCGGACATGTGCCGGTTGCCACCAGAGACGAGTTCGGATTCATCGCGGGGCATACCAACCTGATGATAGACGGGTTGCGC
GACAGGCTGCGGCTGATGGAAGGGCTGGCTGTGGCGCGTGAAGTGCAGGAGACGCTGCTGCCTTCCGGTGTGCCGCATGC
CGCAGCGCAGCCGTCAGCGGACGGTTCCGGACGGCTGGATGTGGCGGGAAGGTGCCTTTACAGCGATGAGACCGGCGGCG
ATTATTATGACTTTCTTGAAAACTGGCTTACGGAAGAAGACGATACGCCCCGTACGGGCATCATTGTGGGTGATGTGACG
GGGCATGGCGTCGGGGCTGCGCTGCTGATGGCTTCCGTGCGGGCGTTTGTGCGTATGCGCGCCGCCACGCCGTGCAGTCC
GGCGGCACTGCTGCGCGACGTGAACAGGCAGGTGGTGCGCGACAGTTACGGAACAGGCCGTTTTGTGACCATGTTTCTGC
TTTGCATCGAGCCGGTTACGCACAGTATTTCGTGGGCTGCAGCCGGTCACGAACCGGCTCTGGTATATCGTGCCGCCGAC
GATTCATTTACGTCGCTGCAGGCTGCTGGTCTGCCGCTGGGAACCATGCCCGGCACGGTGTACGAAACATCCTGCCGCCG
CAGATTGCGTCAGGGCGATGTGGTTCTGCTGTATACCGACGGGCTGGTGGAGGCCCGCAACCGTAAAGGGGAAATGTTCG
GGCGCGACAGAGTGCGCAGAGTCATGCGTATCCATGCCGCCAAAGACGCCGCGGGACTGCTGGAAGCCATGGGCGGAGTG
GTGCGGCGGTTTAAGGACGGTGCGCCGCAGGAGGACGATATAACCATGGTTGCCGTGCGCGTCCTGTAG

Upstream 100 bases:

>100_bases
CCGCAAATCAGAACAAGAGGGCCGCTGCATGCGCGCAATTCTGCTGTATGTTTTTTCCGCTGCCGTACTTACCGTGTACG
GCGGCCGTATCTGACCGTTC

Downstream 100 bases:

>100_bases
TTGTCCCGCAGAACATGACGACAGTAAAAACGGGCACACGGTTGTTTTACCGCGTGCCCGCTTCGTGTCGGTGAGTAACG
CCCTTATGGTTATTGTTCGA

Product: serine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSALPVWKLALVIAAVTGAALLLRRLVVLPHVLSLPVARRAERLGQCDFVLFAGAGVLMALANTVINGVPLLSSGGKLVL
GMVALGVFVSIDLALECERRSIRLAGITEPERLPPRRFSSLTRKFFAVATVVTVLFSLIVILAVFRDLWWFTEAGLNEGS
LRFVKRSILIDLSFIMGMLLVLVINLALSYSRNLRLLFDNQTQVLVRVSNGDMSGHVPVATRDEFGFIAGHTNLMIDGLR
DRLRLMEGLAVAREVQETLLPSGVPHAAAQPSADGSGRLDVAGRCLYSDETGGDYYDFLENWLTEEDDTPRTGIIVGDVT
GHGVGAALLMASVRAFVRMRAATPCSPAALLRDVNRQVVRDSYGTGRFVTMFLLCIEPVTHSISWAAAGHEPALVYRAAD
DSFTSLQAAGLPLGTMPGTVYETSCRRRLRQGDVVLLYTDGLVEARNRKGEMFGRDRVRRVMRIHAAKDAAGLLEAMGGV
VRRFKDGAPQEDDITMVAVRVL

Sequences:

>Translated_502_residues
MSALPVWKLALVIAAVTGAALLLRRLVVLPHVLSLPVARRAERLGQCDFVLFAGAGVLMALANTVINGVPLLSSGGKLVL
GMVALGVFVSIDLALECERRSIRLAGITEPERLPPRRFSSLTRKFFAVATVVTVLFSLIVILAVFRDLWWFTEAGLNEGS
LRFVKRSILIDLSFIMGMLLVLVINLALSYSRNLRLLFDNQTQVLVRVSNGDMSGHVPVATRDEFGFIAGHTNLMIDGLR
DRLRLMEGLAVAREVQETLLPSGVPHAAAQPSADGSGRLDVAGRCLYSDETGGDYYDFLENWLTEEDDTPRTGIIVGDVT
GHGVGAALLMASVRAFVRMRAATPCSPAALLRDVNRQVVRDSYGTGRFVTMFLLCIEPVTHSISWAAAGHEPALVYRAAD
DSFTSLQAAGLPLGTMPGTVYETSCRRRLRQGDVVLLYTDGLVEARNRKGEMFGRDRVRRVMRIHAAKDAAGLLEAMGGV
VRRFKDGAPQEDDITMVAVRVL
>Mature_501_residues
SALPVWKLALVIAAVTGAALLLRRLVVLPHVLSLPVARRAERLGQCDFVLFAGAGVLMALANTVINGVPLLSSGGKLVLG
MVALGVFVSIDLALECERRSIRLAGITEPERLPPRRFSSLTRKFFAVATVVTVLFSLIVILAVFRDLWWFTEAGLNEGSL
RFVKRSILIDLSFIMGMLLVLVINLALSYSRNLRLLFDNQTQVLVRVSNGDMSGHVPVATRDEFGFIAGHTNLMIDGLRD
RLRLMEGLAVAREVQETLLPSGVPHAAAQPSADGSGRLDVAGRCLYSDETGGDYYDFLENWLTEEDDTPRTGIIVGDVTG
HGVGAALLMASVRAFVRMRAATPCSPAALLRDVNRQVVRDSYGTGRFVTMFLLCIEPVTHSISWAAAGHEPALVYRAADD
SFTSLQAAGLPLGTMPGTVYETSCRRRLRQGDVVLLYTDGLVEARNRKGEMFGRDRVRRVMRIHAAKDAAGLLEAMGGVV
RRFKDGAPQEDDITMVAVRVL

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 54627; Mature: 54495

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALPVWKLALVIAAVTGAALLLRRLVVLPHVLSLPVARRAERLGQCDFVLFAGAGVLMA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEHHHHHHHH
LANTVINGVPLLSSGGKLVLGMVALGVFVSIDLALECERRSIRLAGITEPERLPPRRFSS
HHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCCCHHHHHH
LTRKFFAVATVVTVLFSLIVILAVFRDLWWFTEAGLNEGSLRFVKRSILIDLSFIMGMLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVINLALSYSRNLRLLFDNQTQVLVRVSNGDMSGHVPVATRDEFGFIAGHTNLMIDGLR
HHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCCEEECCCCCEEECCCHHHHHHHH
DRLRLMEGLAVAREVQETLLPSGVPHAAAQPSADGSGRLDVAGRCLYSDETGGDYYDFLE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCEEEECCCCCCHHHHHHH
NWLTEEDDTPRTGIIVGDVTGHGVGAALLMASVRAFVRMRAATPCSPAALLRDVNRQVVR
HHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
DSYGTGRFVTMFLLCIEPVTHSISWAAAGHEPALVYRAADDSFTSLQAAGLPLGTMPGTV
CCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCH
YETSCRRRLRQGDVVLLYTDGLVEARNRKGEMFGRDRVRRVMRIHAAKDAAGLLEAMGGV
HHHHHHHHHHCCCEEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VRRFKDGAPQEDDITMVAVRVL
HHHHHCCCCCCCCEEEEEEEEC
>Mature Secondary Structure 
SALPVWKLALVIAAVTGAALLLRRLVVLPHVLSLPVARRAERLGQCDFVLFAGAGVLMA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEHHHHHHHH
LANTVINGVPLLSSGGKLVLGMVALGVFVSIDLALECERRSIRLAGITEPERLPPRRFSS
HHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCCCCHHHHHH
LTRKFFAVATVVTVLFSLIVILAVFRDLWWFTEAGLNEGSLRFVKRSILIDLSFIMGMLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVINLALSYSRNLRLLFDNQTQVLVRVSNGDMSGHVPVATRDEFGFIAGHTNLMIDGLR
HHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCCEEECCCCCEEECCCHHHHHHHH
DRLRLMEGLAVAREVQETLLPSGVPHAAAQPSADGSGRLDVAGRCLYSDETGGDYYDFLE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCEEEECCCCCCHHHHHHH
NWLTEEDDTPRTGIIVGDVTGHGVGAALLMASVRAFVRMRAATPCSPAALLRDVNRQVVR
HHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
DSYGTGRFVTMFLLCIEPVTHSISWAAAGHEPALVYRAADDSFTSLQAAGLPLGTMPGTV
CCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCH
YETSCRRRLRQGDVVLLYTDGLVEARNRKGEMFGRDRVRRVMRIHAAKDAAGLLEAMGGV
HHHHHHHHHHCCCEEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VRRFKDGAPQEDDITMVAVRVL
HHHHHCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]