Click here to switch to the map view.

The map label for this gene is siaP [H]

Identifier: 78355681

GI number: 78355681

Start: 652949

End: 653971

Strand: Direct

Name: siaP [H]

Synonym: Dde_0634

Alternate gene names: 78355681

Gene position: 652949-653971 (Clockwise)

Preceding gene: 78355680

Following gene: 78355682

Centisome position: 17.5

GC content: 61.09

Gene sequence:

>1023_bases
ATGAAAAGTACATTTGCCGCGCTGTTGATCATGGTTGGCTGCCTTGTGTCCGGCGCTCTGCTGACGGGGTCGGAAGCGGC
CGCCGCGCAGCCCGTCACACTGAACTATGCCAACTTTCCGCCTGCATCCACGTTTCCCTGCATCCAGATGGAGCAGTGGG
CACATGAGGTGCGCACCCGTACCCGCGGCAAGGTGGATGTTCTGACCTATCCCGGCGGTACATTGCTGGGTGCCCGCAAC
ATGCTGCGCGGAGTCATGTCGGGGCAGGCGGACATCGGCTGCATCAGTCTTGCCTATCATCCGGGCGTGTTTCCCGTTAT
GAGTGTTTTCGAGCTGCCTCTGGGGTTCACCAGTGCAGAGGCTGCGAGCAGCGTCCTCTGGGAGCTGTATTCCGGCCTGC
GTCCCGCTGAACTGGAGCGTGTCAAAGTGCTCACCATGTTCACTTCTGCTCCTTCGCATTTCATGACAGTGACGCCGGTG
CGTTCGCTGCGTGATCTGCAGGGCATGGAGATACGCGGCGCGGGAACGCTTTCGGCCATACTGGAAAAACTTGGTGCCAC
GCCTGTTTCCATGCCCATGCCCGAAGTGCCGGAAGCGGTGCAGAAGGGGATCATCAAGGGGCTGTTCACATCGCTGGACG
TGATGAAGGACATGAATTTTGCGGAAATGACCGGCCATGTGACCAGAGCGGATCAGGCCGTGTATCCTTTTGCCGTCATT
ATGAACCGCGAAGCGTGGGAGCGCCTGTCACCCGATGTGCAGCAGGTGCTGGACGGGCTGGCGGCGGAGCACGCGGCATG
GACGGGACGCTATCTGGACGCGCATGTGCAGGACTCCATGCGCTGGGCGGAAGAGAAGCACGGCGTGCAGGTGCACACCC
TGCCGGAAGAGGATATCGCCGCCATGCGACGCAGCGTGCAGCCTTTGTTTGACGCATGGGCGCAGAGGGCTGCGGACAAA
GGCGCCGACCCCGATGCAGTGATGCGCACCGTGGATGCTTTGAAGGCGCAGTACGGCGGATAA

Upstream 100 bases:

>100_bases
GTGCATCAGCTTGGAAAAAGGGCTTGATATTCAAGAAACATTATTGATATGAGTGCTAGTCATATGTGGTATGATTTTTA
GCAACCTTTCCGGAGCCGTT

Downstream 100 bases:

>100_bases
CCCGCGGCCATGCAGACAGCAGGGCGTCCGGGGCATGCCGGGCGCTCTTTTTTTGATGCCGCCGCTGGCGGATGAAACGA
GGCGTAAATGGAAAAGATAC

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKSTFAALLIMVGCLVSGALLTGSEAAAAQPVTLNYANFPPASTFPCIQMEQWAHEVRTRTRGKVDVLTYPGGTLLGARN
MLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAEAASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPV
RSLRDLQGMEIRGAGTLSAILEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVI
MNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIAAMRRSVQPLFDAWAQRAADK
GADPDAVMRTVDALKAQYGG

Sequences:

>Translated_340_residues
MKSTFAALLIMVGCLVSGALLTGSEAAAAQPVTLNYANFPPASTFPCIQMEQWAHEVRTRTRGKVDVLTYPGGTLLGARN
MLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAEAASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPV
RSLRDLQGMEIRGAGTLSAILEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVI
MNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIAAMRRSVQPLFDAWAQRAADK
GADPDAVMRTVDALKAQYGG
>Mature_340_residues
MKSTFAALLIMVGCLVSGALLTGSEAAAAQPVTLNYANFPPASTFPCIQMEQWAHEVRTRTRGKVDVLTYPGGTLLGARN
MLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAEAASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPV
RSLRDLQGMEIRGAGTLSAILEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVI
MNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIAAMRRSVQPLFDAWAQRAADK
GADPDAVMRTVDALKAQYGG

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=289, Percent_Identity=24.5674740484429, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36923; Mature: 36923

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTFAALLIMVGCLVSGALLTGSEAAAAQPVTLNYANFPPASTFPCIQMEQWAHEVRTR
CCHHHHHHHHHHHHHHHCHHHCCCCHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
TRGKVDVLTYPGGTLLGARNMLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAE
CCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHH
AASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPVRSLRDLQGMEIRGAGTLSAI
HHHHHHHHHHHCCCCHHHHHHHEEHHHHCCCCCEEEECCHHHHHHCCCCEECCCCHHHHH
LEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCHHHHHHHH
MNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIA
HCHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHH
AMRRSVQPLFDAWAQRAADKGADPDAVMRTVDALKAQYGG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSTFAALLIMVGCLVSGALLTGSEAAAAQPVTLNYANFPPASTFPCIQMEQWAHEVRTR
CCHHHHHHHHHHHHHHHCHHHCCCCHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHH
TRGKVDVLTYPGGTLLGARNMLRGVMSGQADIGCISLAYHPGVFPVMSVFELPLGFTSAE
CCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHH
AASSVLWELYSGLRPAELERVKVLTMFTSAPSHFMTVTPVRSLRDLQGMEIRGAGTLSAI
HHHHHHHHHHHCCCCHHHHHHHEEHHHHCCCCCEEEECCHHHHHHCCCCEECCCCHHHHH
LEKLGATPVSMPMPEVPEAVQKGIIKGLFTSLDVMKDMNFAEMTGHVTRADQAVYPFAVI
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCHHHHHHHH
MNREAWERLSPDVQQVLDGLAAEHAAWTGRYLDAHVQDSMRWAEEKHGVQVHTLPEEDIA
HCHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHH
AMRRSVQPLFDAWAQRAADKGADPDAVMRTVDALKAQYGG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA