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The map label for this gene is murA

Identifier: 78355593

GI number: 78355593

Start: 560473

End: 561723

Strand: Direct

Name: murA

Synonym: Dde_0546

Alternate gene names: 78355593

Gene position: 560473-561723 (Clockwise)

Preceding gene: 78355592

Following gene: 78355594

Centisome position: 15.03

GC content: 60.19

Gene sequence:

>1251_bases
ATGGATAAACTGGTTATCAAAGGTGGCGTGCCGCTGGAAGGCACCATACGGGTCAGCGGTTCGAAAAACGCCTCTTTGCC
AATCCTCATGGCCTCCATCCTGCTGGATGAGCCTGTGATTTACCGCAATGTACCGCGTCTGCGCGATATTCATACCACCA
ACAAACTGCTGGGCATTCTTGGTTGTCCTGCCGAGTTTCAGGGCGATGCAGTGCATGTCAGGCCCTGCGATCTGAATCCT
GAGGCGCCTTACGAACTGGTGAAGACCATGCGCGCTTCCGTGCTATGTCTGGGTCCGCTGCTGGCGCGGCTGGGCGAAGC
GCGGGTGGCATATCCGGGCGGCTGCGCCATAGGAGCCCGTCCGGTGGACCTGCACCTGAGCGCGCTGGAAAAAATGGGTG
CGGAATTCGAGCTTGATTCCGGTTATATAGTGGGCCGCTGCCGTCAGTTGCAGGGGGCGCATATCCGGTTTGACTTTCCC
ACCGTTGGCGGTACCGAAAACCTGCTGATGGCCGCCACGCTGGCCAAAGGCGAAACCATACTGGAAAATGCGGCACGCGA
GCCGGAGGTCATCGATCTGGCCGACTTCCTGTGCGCCTGCGGAGCGGATATTACAGGGCAGGGCACAGATGTCATACGCA
TACGGGGTGTGGAACGCCTGCATGGTTGCGAATACCGCATCATGCCTGACCGCATCGAGGCGGGAACCTTTATGGTGGCG
GCGGGCATAACCCGCGGCAACCTGCTTATCGAAGATTGTCCGGATGACGCGCTGGATGCCGTCAGCCAGAAACTGCGTGA
TATGGGACTGCATGTTTCGCGCGAAGAAGGCGGAACCCGCGTACGCTATCAGGGCCACCTTGAGTCCACCGATATCGTTA
CGCATCCGTATCCGGGATTTCCCACCGACATGCAGGCGCAGTTCATGGCGCTCATGTGCGTGGCAGACGGGTTCGGCATG
GTGGAGGAAACCATTTTTGAAAACCGGTTCATGCATGTGCTCGAGCTGGTACGCATGGGAGCCGATGTGCGTCTTGTGGG
GCGGACAGCCCGCGTGCGCGGCGGCCGTCAGCTGCGGGGGGCGCCGGTCATGGCCTCCGACCTGCGGGCTTCTGCTTCTC
TGGTTCTGGCGGGGCTGGCCGCGCAGGGCGAAACCCATGTACAGCGTATCTACCATCTGGACAGAGGCTACGAGAGCATC
GAGGAAAAACTCTGCCCTGTGGGCGCGGATATCAGGCGCGTGCCTGAATAG

Upstream 100 bases:

>100_bases
CCGTTTGAGACTGAGGCATATATACCCCACAGAAAGCAGCGTCAAGCATAAAACGTGATAAAAATTTCGTCAGGGAAGAA
ATTTTCCCGAGAGGAGATGT

Downstream 100 bases:

>100_bases
CATGTCTGCCATGTTTGTAACGCCTCCGGCTGTGCCGGAGGCGTTTTTTCTTGTCCGCACGCAAGGTGAAGCATGACACG
CAGCACACCCCCGCAAACCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDKLVIKGGVPLEGTIRVSGSKNASLPILMASILLDEPVIYRNVPRLRDIHTTNKLLGILGCPAEFQGDAVHVRPCDLNP
EAPYELVKTMRASVLCLGPLLARLGEARVAYPGGCAIGARPVDLHLSALEKMGAEFELDSGYIVGRCRQLQGAHIRFDFP
TVGGTENLLMAATLAKGETILENAAREPEVIDLADFLCACGADITGQGTDVIRIRGVERLHGCEYRIMPDRIEAGTFMVA
AGITRGNLLIEDCPDDALDAVSQKLRDMGLHVSREEGGTRVRYQGHLESTDIVTHPYPGFPTDMQAQFMALMCVADGFGM
VEETIFENRFMHVLELVRMGADVRLVGRTARVRGGRQLRGAPVMASDLRASASLVLAGLAAQGETHVQRIYHLDRGYESI
EEKLCPVGADIRRVPE

Sequences:

>Translated_416_residues
MDKLVIKGGVPLEGTIRVSGSKNASLPILMASILLDEPVIYRNVPRLRDIHTTNKLLGILGCPAEFQGDAVHVRPCDLNP
EAPYELVKTMRASVLCLGPLLARLGEARVAYPGGCAIGARPVDLHLSALEKMGAEFELDSGYIVGRCRQLQGAHIRFDFP
TVGGTENLLMAATLAKGETILENAAREPEVIDLADFLCACGADITGQGTDVIRIRGVERLHGCEYRIMPDRIEAGTFMVA
AGITRGNLLIEDCPDDALDAVSQKLRDMGLHVSREEGGTRVRYQGHLESTDIVTHPYPGFPTDMQAQFMALMCVADGFGM
VEETIFENRFMHVLELVRMGADVRLVGRTARVRGGRQLRGAPVMASDLRASASLVLAGLAAQGETHVQRIYHLDRGYESI
EEKLCPVGADIRRVPE
>Mature_416_residues
MDKLVIKGGVPLEGTIRVSGSKNASLPILMASILLDEPVIYRNVPRLRDIHTTNKLLGILGCPAEFQGDAVHVRPCDLNP
EAPYELVKTMRASVLCLGPLLARLGEARVAYPGGCAIGARPVDLHLSALEKMGAEFELDSGYIVGRCRQLQGAHIRFDFP
TVGGTENLLMAATLAKGETILENAAREPEVIDLADFLCACGADITGQGTDVIRIRGVERLHGCEYRIMPDRIEAGTFMVA
AGITRGNLLIEDCPDDALDAVSQKLRDMGLHVSREEGGTRVRYQGHLESTDIVTHPYPGFPTDMQAQFMALMCVADGFGM
VEETIFENRFMHVLELVRMGADVRLVGRTARVRGGRQLRGAPVMASDLRASASLVLAGLAAQGETHVQRIYHLDRGYESI
EEKLCPVGADIRRVPE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=53.9568345323741, Blast_Score=429, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_DESDG (Q315P9)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387042.1
- ProteinModelPortal:   Q315P9
- SMR:   Q315P9
- STRING:   Q315P9
- GeneID:   3756493
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_0546
- NMPDR:   fig|207559.3.peg.197
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   DDES207559:DDE_0546-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45235; Mature: 45235

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: ACT_SITE 115-115

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLVIKGGVPLEGTIRVSGSKNASLPILMASILLDEPVIYRNVPRLRDIHTTNKLLGIL
CCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHEE
GCPAEFQGDAVHVRPCDLNPEAPYELVKTMRASVLCLGPLLARLGEARVAYPGGCAIGAR
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
PVDLHLSALEKMGAEFELDSGYIVGRCRQLQGAHIRFDFPTVGGTENLLMAATLAKGETI
CHHHHHHHHHHCCCCEEECCCEEEEEEHHCCCCEEEEECCCCCCCCCEEEEEHHHCCHHH
LENAAREPEVIDLADFLCACGADITGQGTDVIRIRGVERLHGCEYRIMPDRIEAGTFMVA
HHHCCCCCCEEHHHHHHHHCCCCCCCCCCCEEEEECCHHHCCCCEEECCCCCCCCEEEEE
AGITRGNLLIEDCPDDALDAVSQKLRDMGLHVSREEGGTRVRYQGHLESTDIVTHPYPGF
ECCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCEEECCCCCC
PTDMQAQFMALMCVADGFGMVEETIFENRFMHVLELVRMGADVRLVGRTARVRGGRQLRG
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCC
APVMASDLRASASLVLAGLAAQGETHVQRIYHLDRGYESIEEKLCPVGADIRRVPE
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure
MDKLVIKGGVPLEGTIRVSGSKNASLPILMASILLDEPVIYRNVPRLRDIHTTNKLLGIL
CCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHEE
GCPAEFQGDAVHVRPCDLNPEAPYELVKTMRASVLCLGPLLARLGEARVAYPGGCAIGAR
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCC
PVDLHLSALEKMGAEFELDSGYIVGRCRQLQGAHIRFDFPTVGGTENLLMAATLAKGETI
CHHHHHHHHHHCCCCEEECCCEEEEEEHHCCCCEEEEECCCCCCCCCEEEEEHHHCCHHH
LENAAREPEVIDLADFLCACGADITGQGTDVIRIRGVERLHGCEYRIMPDRIEAGTFMVA
HHHCCCCCCEEHHHHHHHHCCCCCCCCCCCEEEEECCHHHCCCCEEECCCCCCCCEEEEE
AGITRGNLLIEDCPDDALDAVSQKLRDMGLHVSREEGGTRVRYQGHLESTDIVTHPYPGF
ECCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCEEECCCCCC
PTDMQAQFMALMCVADGFGMVEETIFENRFMHVLELVRMGADVRLVGRTARVRGGRQLRG
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCC
APVMASDLRASASLVLAGLAAQGETHVQRIYHLDRGYESIEEKLCPVGADIRRVPE
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA