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The map label for this gene is sppA [C]

Identifier: 78355555

GI number: 78355555

Start: 516654

End: 517496

Strand: Direct

Name: sppA [C]

Synonym: Dde_0508

Alternate gene names: 78355555

Gene position: 516654-517496 (Clockwise)

Preceding gene: 78355554

Following gene: 78355557

Centisome position: 13.85

GC content: 61.57

Gene sequence:

>843_bases
ATGATGCTTATACTGGTGGCTGTGGCCCTCTTCTGGGGGGCCATGGCCACTTTGCGTTTGCTGTTCGGCGATGAAGATTT
TTCGGGCGGCCAGCGGCTGGGTCTCATCAACGTGCAGGGCATGCTGCTGGACACCACCCCCTATGTTGATTTTGCCGAAG
AACTGCGCCGCGACCCCGACGTGCGCGGGGTGCTGCTGCGGGTCAATTCGCCGGGCGGGGCGGTGGCGCCTTCGCAGGAG
CTGCACGACGCGGTGAAGCGTCTTGCGACAAGCAAGCCTGTGGTTGTTTCCATGGGGGCCGCTGCTGCTTCCGGCGGCTA
CTACATATCTGTTCCGGCAACCCGCATTGTGGCCAATCCTTCCACGCTTACGGCCAGCATCGGCGTAAAGATGGAAATGG
GCAACGTGCACGAGCTGATGAAGGCGCTGGGCATACACCATGTGGCGCTGACCAGCGGCGAGTTGAAAAATGCCGGTTCT
CCCTTTGCGGAGATGACCCCCCGCGAGCGGGAGTATCTGCAGTCCGTTGTGATGGATATGTACGACCAGTTTGTGCAGGC
CGTGGCCGAAGGACGGCATCTGCCGCCCGAGGATGTGCGGCTGGTTGCGGACGGCCGGGCCATGACCGGCAGACAGGCGT
TGCAGGCGGGGTTGGTTGATATGCTGGGAGACAGACATACGGCCATGCAGGAACTGCTGCGGCTGTGCAACGCCACGGGG
GAACTGCCGGTGCAGGCGGGCCCCGAAGAAAAACGCAGCATTCTGCGCGAGCTGTTTCTTTCCGTGCTGCCTGCCGGTGT
CATTTCCGGTATGGACGATGCCCCGTACCGCTTTTTCTTTTAA

Upstream 100 bases:

>100_bases
GGCGGACAGACTCTGGGCGACATTCTCAAGCTGAAGCTTGAAGAGGATGCAGCAGACAACTAGGCTTACCTTTAGCCAGA
GGCATCCTTTTCTCTTCGGA

Downstream 100 bases:

>100_bases
CGCCATCCGGCGTACTTCTTTTTTCCTTTCTTTTTTCACCGCTGCTCTTCTGCGCCGAGCCTGCTGTCAGTGTGACCTGC
TGTCAGCGTGACCGGCAGGC

Product: signal peptide peptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MMLILVAVALFWGAMATLRLLFGDEDFSGGQRLGLINVQGMLLDTTPYVDFAEELRRDPDVRGVLLRVNSPGGAVAPSQE
LHDAVKRLATSKPVVVSMGAAAASGGYYISVPATRIVANPSTLTASIGVKMEMGNVHELMKALGIHHVALTSGELKNAGS
PFAEMTPREREYLQSVVMDMYDQFVQAVAEGRHLPPEDVRLVADGRAMTGRQALQAGLVDMLGDRHTAMQELLRLCNATG
ELPVQAGPEEKRSILRELFLSVLPAGVISGMDDAPYRFFF

Sequences:

>Translated_280_residues
MMLILVAVALFWGAMATLRLLFGDEDFSGGQRLGLINVQGMLLDTTPYVDFAEELRRDPDVRGVLLRVNSPGGAVAPSQE
LHDAVKRLATSKPVVVSMGAAAASGGYYISVPATRIVANPSTLTASIGVKMEMGNVHELMKALGIHHVALTSGELKNAGS
PFAEMTPREREYLQSVVMDMYDQFVQAVAEGRHLPPEDVRLVADGRAMTGRQALQAGLVDMLGDRHTAMQELLRLCNATG
ELPVQAGPEEKRSILRELFLSVLPAGVISGMDDAPYRFFF
>Mature_280_residues
MMLILVAVALFWGAMATLRLLFGDEDFSGGQRLGLINVQGMLLDTTPYVDFAEELRRDPDVRGVLLRVNSPGGAVAPSQE
LHDAVKRLATSKPVVVSMGAAAASGGYYISVPATRIVANPSTLTASIGVKMEMGNVHELMKALGIHHVALTSGELKNAGS
PFAEMTPREREYLQSVVMDMYDQFVQAVAEGRHLPPEDVRLVADGRAMTGRQALQAGLVDMLGDRHTAMQELLRLCNATG
ELPVQAGPEEKRSILRELFLSVLPAGVISGMDDAPYRFFF

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=184, Percent_Identity=39.6739130434783, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787527, Length=161, Percent_Identity=32.2981366459627, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 30266; Mature: 30266

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLILVAVALFWGAMATLRLLFGDEDFSGGQRLGLINVQGMLLDTTPYVDFAEELRRDPD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCHHHHHHHCCCCC
VRGVLLRVNSPGGAVAPSQELHDAVKRLATSKPVVVSMGAAAASGGYYISVPATRIVANP
CCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCEEEECC
STLTASIGVKMEMGNVHELMKALGIHHVALTSGELKNAGSPFAEMTPREREYLQSVVMDM
CCEEEECCEEEECCCHHHHHHHHCCHHEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHH
YDQFVQAVAEGRHLPPEDVRLVADGRAMTGRQALQAGLVDMLGDRHTAMQELLRLCNATG
HHHHHHHHHCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
ELPVQAGPEEKRSILRELFLSVLPAGVISGMDDAPYRFFF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMLILVAVALFWGAMATLRLLFGDEDFSGGQRLGLINVQGMLLDTTPYVDFAEELRRDPD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCHHHHHHHCCCCC
VRGVLLRVNSPGGAVAPSQELHDAVKRLATSKPVVVSMGAAAASGGYYISVPATRIVANP
CCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCEEEECC
STLTASIGVKMEMGNVHELMKALGIHHVALTSGELKNAGSPFAEMTPREREYLQSVVMDM
CCEEEECCEEEECCCHHHHHHHHCCHHEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHH
YDQFVQAVAEGRHLPPEDVRLVADGRAMTGRQALQAGLVDMLGDRHTAMQELLRLCNATG
HHHHHHHHHCCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
ELPVQAGPEEKRSILRELFLSVLPAGVISGMDDAPYRFFF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]