Click here to switch to the map view.

The map label for this gene is fdhA [H]

Identifier: 78355519

GI number: 78355519

Start: 482267

End: 482668

Strand: Direct

Name: fdhA [H]

Synonym: Dde_0472

Alternate gene names: 78355519

Gene position: 482267-482668 (Clockwise)

Preceding gene: 78355517

Following gene: 78355520

Centisome position: 12.93

GC content: 54.23

Gene sequence:

>402_bases
ATGAAAGAAGTATTAACAACGTGTCCTTACTGCGGTACAGGGTGCGCTTTTTACCTTCAGGTGCATGACGATACTGTGAC
AGGAGTCCGTCCGGCCGTCAGCAACACGGTGAATAAAGGCAGGCTGTGTTCCAAGGGGCATTTCGGCTTTGATTTCATTC
ACCATGGTGACCGGCTGAAAACTCCGCTTATCCGCAGGGATGGCCGGCTGGTGCCCTGCAGCTGGGAAGAAGCCTACGAT
TGTATCACATCGCGGCTTTCAGAGATTATCCGTCAGAGCGGGCCCGATGCCGTGGCAGGGTTCAGTTCCGCCCGTTGTAC
CAACGAAGAAAATTATCTGATGCAGAAGTTCATGCGTGCGGCCGTCGGCACCAATAATGTCGACCACTGCGCCCGTCTCT
GA

Upstream 100 bases:

>100_bases
TGTCCGTAAGCCAAGTGTAAAATGCGGCTGCTACGGAATGCAACAGCAACGCCGGAATGCAGTTACTGCTTTCCGGCATA
CTGCGTACAGGTGGTAAAAG

Downstream 100 bases:

>100_bases
CACGCTCCCACCGTGGCCGGTCTGGCCGCAGCATTCGGAAGCGGAGCCATGACGAATTCCATTGATGAACTGGAGAGCAT
GGGGGCCGGCGATGTGATTT

Product: formate dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MKEVLTTCPYCGTGCAFYLQVHDDTVTGVRPAVSNTVNKGRLCSKGHFGFDFIHHGDRLKTPLIRRDGRLVPCSWEEAYD
CITSRLSEIIRQSGPDAVAGFSSARCTNEENYLMQKFMRAAVGTNNVDHCARL

Sequences:

>Translated_133_residues
MKEVLTTCPYCGTGCAFYLQVHDDTVTGVRPAVSNTVNKGRLCSKGHFGFDFIHHGDRLKTPLIRRDGRLVPCSWEEAYD
CITSRLSEIIRQSGPDAVAGFSSARCTNEENYLMQKFMRAAVGTNNVDHCARL
>Mature_133_residues
MKEVLTTCPYCGTGCAFYLQVHDDTVTGVRPAVSNTVNKGRLCSKGHFGFDFIHHGDRLKTPLIRRDGRLVPCSWEEAYD
CITSRLSEIIRQSGPDAVAGFSSARCTNEENYLMQKFMRAAVGTNNVDHCARL

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=140, Percent_Identity=49.2857142857143, Blast_Score=131, Evalue=2e-32,
Organism=Escherichia coli, GI1788534, Length=132, Percent_Identity=29.5454545454545, Blast_Score=83, Evalue=6e-18,
Organism=Escherichia coli, GI3868720, Length=153, Percent_Identity=32.0261437908497, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 14804; Mature: 14804

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
6.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVLTTCPYCGTGCAFYLQVHDDTVTGVRPAVSNTVNKGRLCSKGHFGFDFIHHGDRLK
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHCCCCCCC
TPLIRRDGRLVPCSWEEAYDCITSRLSEIIRQSGPDAVAGFSSARCTNEENYLMQKFMRA
CCHHHCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHH
AVGTNNVDHCARL
HHCCCCHHHHHCC
>Mature Secondary Structure
MKEVLTTCPYCGTGCAFYLQVHDDTVTGVRPAVSNTVNKGRLCSKGHFGFDFIHHGDRLK
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHCCCCCCC
TPLIRRDGRLVPCSWEEAYDCITSRLSEIIRQSGPDAVAGFSSARCTNEENYLMQKFMRA
CCHHHCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHH
AVGTNNVDHCARL
HHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]