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The map label for this gene is rfbB [C]

Identifier: 78355474

GI number: 78355474

Start: 425663

End: 426580

Strand: Direct

Name: rfbB [C]

Synonym: Dde_0427

Alternate gene names: 78355474

Gene position: 425663-426580 (Clockwise)

Preceding gene: 78355473

Following gene: 78355475

Centisome position: 11.41

GC content: 61.76

Gene sequence:

>918_bases
ATGGTTAAAACGGTTCTGGTGACAGGGGTCAACGGCTTTATCGGCAGCCATGTGGCCGCGCTGCTGGGCAAAAGTCACCG
TGTATACGGCACGGGCGGCGCGCCTGCCTGTTCCGTGCCGCTGGCCGGATACAGGCAGATGGTTCTGCCCGACCCGCAGC
TGGCCGCGTTCATGCGTCAGGTGCGGCCCGATGTGGTCGTCCATTGTGCCGGTCGCGGCTCCATACCGTTTTCCGTCAAC
CATCCTGCAGAGGATTTTGACGCGGGACCGCGTCTTGTTGCCCATGTGCTGGACAGCATGCGTCGTGCGGCAGTGCCTGC
GCGGTTCTTTTTTCCTTCCAGCGCTGCGGTGTACGGTAATCCGGAGCGCCTGCCCGTATCCGAGGACGCCCCGCTGTGCC
CTGTTTCGCCCTACGGTTGTCACAAGGTCCTCAGCGAAAAACTTATCAGCCAGTATCACAGCCTGTACGGCATTGAGTAC
GTGGTTCTGCGGGTGTTTTCCTGCTACGGCGAGGGGCTTTCAAAACAGCTGTTGTGGGATGCGGCGGTGAAGGCCTGTGC
TGGCAGGGTGGAACTGAGCGGCACCGGCGAAGAAACACGTGATTTCATTCATGTGCACGATCTGGCCCGGCTGGCTGAAC
TGCTGATGCTGCGTGATGTGTCGTGCGTTACGCTCAACGCCGCAAGCGGCAGACAGGTTTCTGTAAAAGAGCTGGCCGGT
CTGCTGATGCGCGGGCTCGAGGCTGATGTGCCTGTGCTGTTCAGCGGCGCACAGCGGCAGGGCGACCCGCTGCGCTGGCA
GGCCGATGTTGCGCGCATGCAGTCGCTTGGTTTTGAGCCGCATATTTCTCTGGAAGAAGGTGTGCGCCGCTTTGCCCGCT
GGTTCAGGCAGCAAGGGGCCCGCCGCAACGGCAGCTGA

Upstream 100 bases:

>100_bases
CGGCCCGCAAGGCCGAGCGTCAGGCTTCGAGACAGGCGGGACAGTCCTTGTGCGCAGCGGCGCAGAATCAGGAATCCCCG
GCCGGGCGGCAGGAGACATG

Downstream 100 bases:

>100_bases
CGGCGTGCGCGCCGCGCAATACGCAACACGATTCAAGGAGGCGGCAGTGTCCACACTCGGACTTGTCATTCAATGGGGCA
GTGACGGCTGGCAGGGCGGT

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MVKTVLVTGVNGFIGSHVAALLGKSHRVYGTGGAPACSVPLAGYRQMVLPDPQLAAFMRQVRPDVVVHCAGRGSIPFSVN
HPAEDFDAGPRLVAHVLDSMRRAAVPARFFFPSSAAVYGNPERLPVSEDAPLCPVSPYGCHKVLSEKLISQYHSLYGIEY
VVLRVFSCYGEGLSKQLLWDAAVKACAGRVELSGTGEETRDFIHVHDLARLAELLMLRDVSCVTLNAASGRQVSVKELAG
LLMRGLEADVPVLFSGAQRQGDPLRWQADVARMQSLGFEPHISLEEGVRRFARWFRQQGARRNGS

Sequences:

>Translated_305_residues
MVKTVLVTGVNGFIGSHVAALLGKSHRVYGTGGAPACSVPLAGYRQMVLPDPQLAAFMRQVRPDVVVHCAGRGSIPFSVN
HPAEDFDAGPRLVAHVLDSMRRAAVPARFFFPSSAAVYGNPERLPVSEDAPLCPVSPYGCHKVLSEKLISQYHSLYGIEY
VVLRVFSCYGEGLSKQLLWDAAVKACAGRVELSGTGEETRDFIHVHDLARLAELLMLRDVSCVTLNAASGRQVSVKELAG
LLMRGLEADVPVLFSGAQRQGDPLRWQADVARMQSLGFEPHISLEEGVRRFARWFRQQGARRNGS
>Mature_305_residues
MVKTVLVTGVNGFIGSHVAALLGKSHRVYGTGGAPACSVPLAGYRQMVLPDPQLAAFMRQVRPDVVVHCAGRGSIPFSVN
HPAEDFDAGPRLVAHVLDSMRRAAVPARFFFPSSAAVYGNPERLPVSEDAPLCPVSPYGCHKVLSEKLISQYHSLYGIEY
VVLRVFSCYGEGLSKQLLWDAAVKACAGRVELSGTGEETRDFIHVHDLARLAELLMLRDVSCVTLNAASGRQVSVKELAG
LLMRGLEADVPVLFSGAQRQGDPLRWQADVARMQSLGFEPHISLEEGVRRFARWFRQQGARRNGS

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=312, Percent_Identity=26.2820512820513, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=26.8221574344023, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=26.8221574344023, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=26.8221574344023, Blast_Score=78, Evalue=9e-15,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=24.188790560472, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994969, Length=333, Percent_Identity=22.8228228228228, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=26.7062314540059, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788365, Length=274, Percent_Identity=24.8175182481752, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=25.7309941520468, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=26.031746031746, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33207; Mature: 33207

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKTVLVTGVNGFIGSHVAALLGKSHRVYGTGGAPACSVPLAGYRQMVLPDPQLAAFMRQ
CCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCHHCCCCHHHHHHHHH
VRPDVVVHCAGRGSIPFSVNHPAEDFDAGPRLVAHVLDSMRRAAVPARFFFPSSAAVYGN
HCCCEEEEECCCCCCCEECCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCEECCC
PERLPVSEDAPLCPVSPYGCHKVLSEKLISQYHSLYGIEYVVLRVFSCYGEGLSKQLLWD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAVKACAGRVELSGTGEETRDFIHVHDLARLAELLMLRDVSCVTLNAASGRQVSVKELAG
HHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECHHHHHH
LLMRGLEADVPVLFSGAQRQGDPLRWQADVARMQSLGFEPHISLEEGVRRFARWFRQQGA
HHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
RRNGS
CCCCC
>Mature Secondary Structure
MVKTVLVTGVNGFIGSHVAALLGKSHRVYGTGGAPACSVPLAGYRQMVLPDPQLAAFMRQ
CCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCHHCCCCHHHHHHHHH
VRPDVVVHCAGRGSIPFSVNHPAEDFDAGPRLVAHVLDSMRRAAVPARFFFPSSAAVYGN
HCCCEEEEECCCCCCCEECCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCEECCC
PERLPVSEDAPLCPVSPYGCHKVLSEKLISQYHSLYGIEYVVLRVFSCYGEGLSKQLLWD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAVKACAGRVELSGTGEETRDFIHVHDLARLAELLMLRDVSCVTLNAASGRQVSVKELAG
HHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECHHHHHH
LLMRGLEADVPVLFSGAQRQGDPLRWQADVARMQSLGFEPHISLEEGVRRFARWFRQQGA
HHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
RRNGS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]