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The map label for this gene is nudG [H]

Identifier: 78355298

GI number: 78355298

Start: 235047

End: 235439

Strand: Direct

Name: nudG [H]

Synonym: Dde_0251

Alternate gene names: 78355298

Gene position: 235047-235439 (Clockwise)

Preceding gene: 78355297

Following gene: 78355299

Centisome position: 6.3

GC content: 63.61

Gene sequence:

>393_bases
ATGAAATCTGTTGATGTGGTGGCGGGCATTCTGTGGCGCGGCGGCCGTTTTCTGGCAGTGGAGCGCCCGCAGGGCAGACC
CCGTGCCGGCTTCTGGGAGTTTCCCGGCGGCAAGATAGAACAGGGCGAAACTCCGGAACAGGCTCTGGCGCGCGAACTGA
AGGAAGAGCTGGGCGTGGATGTCCGGGATTTCTGCTTCTGGCGCAGCGTGGAGCATGCTTACGAGGATCTCGCCGTGCGC
CTGAGGTTTTTTCATGTGACCGGCTTTGCGGGCGAGCCTCAGGGGCTGGAAGGTCACAGGCTGGCGTGGCTGCGGTGCGA
CGAGGCGCTGCGGCTGCGTTTTCTGGAGGCGGACAGGCCGCTTGTGGCCGATCTGGCCACCATCACATTCTGA

Upstream 100 bases:

>100_bases
TGGAATCCGGCATGGCGGACATAGAGGCCCGCAGACAGCAGGCCGGTTTGTGATGTTTTTATTTGTCGCCGGAAGTGTGG
CGTCATGATACGGGAACAGT

Downstream 100 bases:

>100_bases
CGGGGGATACCCATGAGCGCACTGTTATTTGTCATGGCGCTGCTGGCGGGGGCCACCCTGCCCACGCAGGCGGGGATAAA
CAGCGGACTTCAGGCGCACT

Product: mutator mutT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MKSVDVVAGILWRGGRFLAVERPQGRPRAGFWEFPGGKIEQGETPEQALARELKEELGVDVRDFCFWRSVEHAYEDLAVR
LRFFHVTGFAGEPQGLEGHRLAWLRCDEALRLRFLEADRPLVADLATITF

Sequences:

>Translated_130_residues
MKSVDVVAGILWRGGRFLAVERPQGRPRAGFWEFPGGKIEQGETPEQALARELKEELGVDVRDFCFWRSVEHAYEDLAVR
LRFFHVTGFAGEPQGLEGHRLAWLRCDEALRLRFLEADRPLVADLATITF
>Mature_130_residues
MKSVDVVAGILWRGGRFLAVERPQGRPRAGFWEFPGGKIEQGETPEQALARELKEELGVDVRDFCFWRSVEHAYEDLAVR
LRFFHVTGFAGEPQGLEGHRLAWLRCDEALRLRFLEADRPLVADLATITF

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=122, Percent_Identity=39.344262295082, Blast_Score=86, Evalue=6e-19,
Organism=Escherichia coli, GI1786288, Length=126, Percent_Identity=35.7142857142857, Blast_Score=76, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14855; Mature: 14855

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVDVVAGILWRGGRFLAVERPQGRPRAGFWEFPGGKIEQGETPEQALARELKEELGVD
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
VRDFCFWRSVEHAYEDLAVRLRFFHVTGFAGEPQGLEGHRLAWLRCDEALRLRFLEADRP
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEECCHHHHEEHHCCCCC
LVADLATITF
HHHHHHHHCC
>Mature Secondary Structure
MKSVDVVAGILWRGGRFLAVERPQGRPRAGFWEFPGGKIEQGETPEQALARELKEELGVD
CCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
VRDFCFWRSVEHAYEDLAVRLRFFHVTGFAGEPQGLEGHRLAWLRCDEALRLRFLEADRP
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEECCHHHHEEHHCCCCC
LVADLATITF
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]