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The map label for this gene is yqhT [H]

Identifier: 78355264

GI number: 78355264

Start: 199621

End: 200691

Strand: Direct

Name: yqhT [H]

Synonym: Dde_0217

Alternate gene names: 78355264

Gene position: 199621-200691 (Clockwise)

Preceding gene: 78355263

Following gene: 78355265

Centisome position: 5.35

GC content: 60.78

Gene sequence:

>1071_bases
ATGAACGCGGAACATTATGCGCGGCGGCGCGAACGCCTGCGTCCGCTGCTGCGCGAAAACGGGCTGGACGCCCTGCTTGT
CAGTCTGGATGCCAACCGGTTTTACCTGAGCGGTTTTGAACTGCATGACGCGCAGATAAATGAAAGTTGCGGCCGTCTGC
TCATAACAGCCGACGGACCGGACTGGCTGTGCACCGACCCGCGGTTTGAAGAGGCGGCCCGCCGTCTGTGGGACAGGGAG
CACATTTTCATTTACAGCGGCAATGCCGCGGAAAGACTGCGCGAGTTTGTAAAGGGACGTTTTTCCGGTGCCATAGGATA
CGAGTCGTCCTGCGTCAGCATGGCGTTTTACGATTCGTTCGCCGGCGGATTGTCTCTGAAAAAGGCCGACGGGCTGGTTG
AAAAGCTGCGTGTGATAAAGGAACCGGAAGAAATCGCACGTCTGGAACGCGCATGCGCCCTGAACCACAGGTTGATGGAA
TGGCTGCCGCAGGTGCTGTATCCGGGCAGAACCGAGGCGCAGGTGGCGTGGGACATTGAAAAGTTTTTCCGTGAAAACGG
CGCCTCCGAGCTGGCTTTTCCCAGCATTGTGGCGGCCGGAGCCAACGCGGCCATGTGCCATGCCATTCCCGACGACACGG
TGCTGCATGAAAACTGCCCCCTGCTGGTGGATGTGGGCTGCCGCGTGGACGATTACTGTTCTGACCAGACCCGTACGTTC
TGGGTGGGAGACCGCCCTGCGGACGAGTTTCTGCGCACCCGCGACATGGTGCAGCACGCCCAGCGGGTTGCCATCGACAT
CATGCGCCCGGGCATGCCCCTTGCCGATGCGCACAATATGGCACTGGCCGTTTTTGAACGGCACGGCGTAGCAGCCGCAT
TCACGCATTCGCTGGGCCACGGCATAGGGCTGCAGACGCACGAGGCGCCCGCGGTCAACCACCGCACCGATGCCCGTCTG
GAACCGGGCATGGTCATCACCGTGGAACCGGGGTTGTATTTTCCTGTATGGGGCGGTGTCCGCTGGGAATATATGGTCCA
CTGCACCGAGGATGGTGTGCGGGTGCTGTAG

Upstream 100 bases:

>100_bases
AAGTGGCCAACATGGATCATTCCGTGATGCAGGGGGTTGAGTGGGCCGAGCGCATGGTGCAGGGCACGCCGGAAACAACT
TACACTATTCAGGAAAAGTG

Downstream 100 bases:

>100_bases
CGCTGTTCTGCGGCGTGTGTGCCGCATCTGACTGCCGACGGAAAAACCGGCCGGAAAACGCGCAGAGTGTGTTTTCCGGC
CGGTTTTCTGTTTGTTTCAA

Product: M24 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNAEHYARRRERLRPLLRENGLDALLVSLDANRFYLSGFELHDAQINESCGRLLITADGPDWLCTDPRFEEAARRLWDRE
HIFIYSGNAAERLREFVKGRFSGAIGYESSCVSMAFYDSFAGGLSLKKADGLVEKLRVIKEPEEIARLERACALNHRLME
WLPQVLYPGRTEAQVAWDIEKFFRENGASELAFPSIVAAGANAAMCHAIPDDTVLHENCPLLVDVGCRVDDYCSDQTRTF
WVGDRPADEFLRTRDMVQHAQRVAIDIMRPGMPLADAHNMALAVFERHGVAAAFTHSLGHGIGLQTHEAPAVNHRTDARL
EPGMVITVEPGLYFPVWGGVRWEYMVHCTEDGVRVL

Sequences:

>Translated_356_residues
MNAEHYARRRERLRPLLRENGLDALLVSLDANRFYLSGFELHDAQINESCGRLLITADGPDWLCTDPRFEEAARRLWDRE
HIFIYSGNAAERLREFVKGRFSGAIGYESSCVSMAFYDSFAGGLSLKKADGLVEKLRVIKEPEEIARLERACALNHRLME
WLPQVLYPGRTEAQVAWDIEKFFRENGASELAFPSIVAAGANAAMCHAIPDDTVLHENCPLLVDVGCRVDDYCSDQTRTF
WVGDRPADEFLRTRDMVQHAQRVAIDIMRPGMPLADAHNMALAVFERHGVAAAFTHSLGHGIGLQTHEAPAVNHRTDARL
EPGMVITVEPGLYFPVWGGVRWEYMVHCTEDGVRVL
>Mature_356_residues
MNAEHYARRRERLRPLLRENGLDALLVSLDANRFYLSGFELHDAQINESCGRLLITADGPDWLCTDPRFEEAARRLWDRE
HIFIYSGNAAERLREFVKGRFSGAIGYESSCVSMAFYDSFAGGLSLKKADGLVEKLRVIKEPEEIARLERACALNHRLME
WLPQVLYPGRTEAQVAWDIEKFFRENGASELAFPSIVAAGANAAMCHAIPDDTVLHENCPLLVDVGCRVDDYCSDQTRTF
WVGDRPADEFLRTRDMVQHAQRVAIDIMRPGMPLADAHNMALAVFERHGVAAAFTHSLGHGIGLQTHEAPAVNHRTDARL
EPGMVITVEPGLYFPVWGGVRWEYMVHCTEDGVRVL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=426, Percent_Identity=25.3521126760563, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI40385867, Length=203, Percent_Identity=28.0788177339901, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788728, Length=350, Percent_Identity=30.5714285714286, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789275, Length=221, Percent_Identity=27.1493212669683, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786364, Length=203, Percent_Identity=27.0935960591133, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71989583, Length=261, Percent_Identity=24.1379310344828, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323273, Length=226, Percent_Identity=26.1061946902655, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320922, Length=275, Percent_Identity=24.7272727272727, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321118, Length=237, Percent_Identity=24.8945147679325, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920384, Length=231, Percent_Identity=30.3030303030303, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40108; Mature: 40108

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEHYARRRERLRPLLRENGLDALLVSLDANRFYLSGFELHDAQINESCGRLLITADGP
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECEEEEHHHHHHCCCEEEEEECCC
DWLCTDPRFEEAARRLWDREHIFIYSGNAAERLREFVKGRFSGAIGYESSCVSMAFYDSF
CCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AGGLSLKKADGLVEKLRVIKEPEEIARLERACALNHRLMEWLPQVLYPGRTEAQVAWDIE
HCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHH
KFFRENGASELAFPSIVAAGANAAMCHAIPDDTVLHENCPLLVDVGCRVDDYCSDQTRTF
HHHHHCCCCCCCCHHHHHCCCCCEEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCEEE
WVGDRPADEFLRTRDMVQHAQRVAIDIMRPGMPLADAHNMALAVFERHGVAAAFTHSLGH
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHCCCHHHHHHHHCC
GIGLQTHEAPAVNHRTDARLEPGMVITVEPGLYFPVWGGVRWEYMVHCTEDGVRVL
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MNAEHYARRRERLRPLLRENGLDALLVSLDANRFYLSGFELHDAQINESCGRLLITADGP
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECEEEEHHHHHHCCCEEEEEECCC
DWLCTDPRFEEAARRLWDREHIFIYSGNAAERLREFVKGRFSGAIGYESSCVSMAFYDSF
CCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AGGLSLKKADGLVEKLRVIKEPEEIARLERACALNHRLMEWLPQVLYPGRTEAQVAWDIE
HCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHH
KFFRENGASELAFPSIVAAGANAAMCHAIPDDTVLHENCPLLVDVGCRVDDYCSDQTRTF
HHHHHCCCCCCCCHHHHHCCCCCEEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCEEE
WVGDRPADEFLRTRDMVQHAQRVAIDIMRPGMPLADAHNMALAVFERHGVAAAFTHSLGH
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHCCCHHHHHHHHCC
GIGLQTHEAPAVNHRTDARLEPGMVITVEPGLYFPVWGGVRWEYMVHCTEDGVRVL
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]