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The map label for this gene is nhaA2 [H]

Identifier: 78355210

GI number: 78355210

Start: 149027

End: 149839

Strand: Direct

Name: nhaA2 [H]

Synonym: Dde_0163

Alternate gene names: 78355210

Gene position: 149027-149839 (Clockwise)

Preceding gene: 78355209

Following gene: 78355211

Centisome position: 4.0

GC content: 56.95

Gene sequence:

>813_bases
ATGAAACGACTGTTGAAAAATCAAGGTGCCTTCTTAGGTGCCATGTTGATGGCCGCTGTGGTTGTTTTGTCTGCTGCACC
GCAGGCGCGGGCGGCAGCCGAACAGGACCGGCTGAAAGACATGGTGCGCGAGGTTCTGCGCGATAACCCCGGGCTGGTTA
TGGATGTGCTGCGGCAGAATCCGGAACAGGTGCTGGATATCGTGCGTGACGGTAACAGAATTGCCAGAGACAGAGCCATG
CGTGCCCAGTGGCAGGCCGATATGACACAGCCCAAGCAGGTAAAACTGGACGGGCGTCCCGTGCGCGGGCCGCAGGATGC
TCCGGTGACCATTGTGGCATACTCGGATTTTACCTGTCCCTACTGCGCTCAGGCTGCCGGCACCGTGGCCGCTCTTATGG
AGCATTACAAAGGCAAGGTGCGGTTGGTTTTTAAGCATTATCCTTTAAAATCACATGATAATGCCGAAACAGCTTCACGC
ATGTTTGTGGCTGCCGCCATGCAGGACGAAGCAAAAGCATGGGCGTTGTACGACGCCATGTTTGTTGAGCGGGCCCGCGT
GATAAAGGAAGGCAGTGCCTTTATTTCTGCCAAAGCCGCAGAACTGGGACTGGATGCCGCACGGCTTGCGCGTGACGCGC
AAAGTGACGCGGCAACACGAATTTTGCGCGAAGACAGACAGGAAGCCGAAAACCTTGGGCTGGAAGGAACCCCGACATTT
CTTGTGAATGACATCGTCGTGCGTGGCTCGCTGCCTCTGCCACAGTTTGCGGATGCCGTGGATATGGCCTGGGCAAAAGC
CGCCGGTCGCTGA

Upstream 100 bases:

>100_bases
GCAGCAGCTTGTCCATAGGGGCCGGTAACGGTGTGCCGCTTGCCCGCGGCGTGGGCGCGGTGTACACACACCCGAGTTGT
ACTCTTTATCGGAGGATTAC

Downstream 100 bases:

>100_bases
GCCTGCCGGTAGACGTAACGGGAATGACTCCCCTGTCTGTGAAAAATGACCGGAAACCTTTTTGAATATGTCTCCGGCGG
GCAGGGAGATGATCGCCCTG

Product: DSBA-like thioredoxin domain-containing protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKRLLKNQGAFLGAMLMAAVVVLSAAPQARAAAEQDRLKDMVREVLRDNPGLVMDVLRQNPEQVLDIVRDGNRIARDRAM
RAQWQADMTQPKQVKLDGRPVRGPQDAPVTIVAYSDFTCPYCAQAAGTVAALMEHYKGKVRLVFKHYPLKSHDNAETASR
MFVAAAMQDEAKAWALYDAMFVERARVIKEGSAFISAKAAELGLDAARLARDAQSDAATRILREDRQEAENLGLEGTPTF
LVNDIVVRGSLPLPQFADAVDMAWAKAAGR

Sequences:

>Translated_270_residues
MKRLLKNQGAFLGAMLMAAVVVLSAAPQARAAAEQDRLKDMVREVLRDNPGLVMDVLRQNPEQVLDIVRDGNRIARDRAM
RAQWQADMTQPKQVKLDGRPVRGPQDAPVTIVAYSDFTCPYCAQAAGTVAALMEHYKGKVRLVFKHYPLKSHDNAETASR
MFVAAAMQDEAKAWALYDAMFVERARVIKEGSAFISAKAAELGLDAARLARDAQSDAATRILREDRQEAENLGLEGTPTF
LVNDIVVRGSLPLPQFADAVDMAWAKAAGR
>Mature_270_residues
MKRLLKNQGAFLGAMLMAAVVVLSAAPQARAAAEQDRLKDMVREVLRDNPGLVMDVLRQNPEQVLDIVRDGNRIARDRAM
RAQWQADMTQPKQVKLDGRPVRGPQDAPVTIVAYSDFTCPYCAQAAGTVAALMEHYKGKVRLVFKHYPLKSHDNAETASR
MFVAAAMQDEAKAWALYDAMFVERARVIKEGSAFISAKAAELGLDAARLARDAQSDAATRILREDRQEAENLGLEGTPTF
LVNDIVVRGSLPLPQFADAVDMAWAKAAGR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 29662; Mature: 29662

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLKNQGAFLGAMLMAAVVVLSAAPQARAAAEQDRLKDMVREVLRDNPGLVMDVLRQN
CCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
PEQVLDIVRDGNRIARDRAMRAQWQADMTQPKQVKLDGRPVRGPQDAPVTIVAYSDFTCP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCH
YCAQAAGTVAALMEHYKGKVRLVFKHYPLKSHDNAETASRMFVAAAMQDEAKAWALYDAM
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVERARVIKEGSAFISAKAAELGLDAARLARDAQSDAATRILREDRQEAENLGLEGTPTF
HHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LVNDIVVRGSLPLPQFADAVDMAWAKAAGR
HHHHEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRLLKNQGAFLGAMLMAAVVVLSAAPQARAAAEQDRLKDMVREVLRDNPGLVMDVLRQN
CCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
PEQVLDIVRDGNRIARDRAMRAQWQADMTQPKQVKLDGRPVRGPQDAPVTIVAYSDFTCP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCH
YCAQAAGTVAALMEHYKGKVRLVFKHYPLKSHDNAETASRMFVAAAMQDEAKAWALYDAM
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVERARVIKEGSAFISAKAAELGLDAARLARDAQSDAATRILREDRQEAENLGLEGTPTF
HHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LVNDIVVRGSLPLPQFADAVDMAWAKAAGR
HHHHEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA