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The map label for this gene is hyuA [H]

Identifier: 78355139

GI number: 78355139

Start: 84280

End: 86007

Strand: Direct

Name: hyuA [H]

Synonym: Dde_0092

Alternate gene names: 78355139

Gene position: 84280-86007 (Clockwise)

Preceding gene: 78355138

Following gene: 78355140

Centisome position: 2.26

GC content: 64.7

Gene sequence:

>1728_bases
ATGAGTGACTTTACAGAGCAGAACCGGACGGCAGCCCCTGACGGCGGGTTTGTCATCGGAGTGGATGCCGGCGGCACATA
CACCGATGCCGTGGTGGTGGACATAGCCGGAGGGCACGCCGTGGCGCGTGCCAAGAGGCCCACAACACATTATCAGCCCA
GTACGGGGGTTGCTGCAGCCATAGGTGATGTGCTGCTGAAGGCAGGCATCAATCCGGCTGATGTCCGCAGCACGGCGGTT
TCCACCACGCTGGCCACCAACGCCCTGCTGGAAAACAAAGGCGTGGATGTGGGGCTGATCGTCATCGGTTTCAACCAGCG
TATGGAGGTTCCTGCCGCTGCCGCCCGTTATGTGCCCGGCGGCCACAGGCAGGACGGTACCGAAGCTGAACCGCTGGGGT
TGGAATTTTTGCTGGATCACCTGAAAGACCTGCATGGCAGGGTGGATGCATATGCGGTGTGCTCGCTGCACAGTTACGCC
AATCCGGCTCATGAGCTGGTGGCGGCAGAGGCCATCCGGCTGACCAGCGGTCTGCCCGTGTTCTGTTCGCACGAGGTGAG
CATGCAGGCGGGAATGCGTGAACGGGCCACCACGGCGGTGCTGAATGCCCGCTTGCTGCCGGTGATGGAACAGTTTCTGG
CCGGTGTGCGCAAGGCTCTGGACGAGCAGGGCATCAGGGGAACGGTGCAGGTGGTGCGCGGCGACGCTTCGACCATGGGC
ATGGAACAGGCGGTGCGCAGTGCGGCCAGCACAGTGGCCAGCGGGCCCGCGGCCACGGCATGCTTCGGTGCGCAATACGC
GGCCACGGCGTGCTGCGACTATGCGGGGCAGCAGCCGCAGGACGTGCTGGTGGTTGATGTGGGCGGAACAACCACTGATA
TGACCATTGTGCACGAGGGGCGGCCGGTTATTGATACCGGCGGCATGCTGGTGGGTGAATGGCAGACGCACGTAGATGCC
GTGGAGATGTTTACCGTGGCTGTGGGGGGCGACAGTCTGGTGGAACTGGACCCCGTGGGAACACTGTCTCTCGGACCTGC
GCGGGTGGTGCCCGTATGCATGGCCGCCGCCTGGGGGGTGGAATTGCCCGACCCTGCCTTGTGGGCAGGTCCGGGGCTGG
GCGGGCGCTGTGTCTGTGCCGGTGCCGGTCTGGAAGGCGATGCCTGCTCCGGCGATGCGCTGCTGCAGCTGCTGTGCGCA
CGGCGCGCTATGCCGCTGGCAGAACTGCTGGCCGCGTTGTCCATGGCCGAGGTCACCTATAACGGCCGCATGATGCGGCT
GGCCCGCGGGCAGAAAATTTTTGAGTGCGGGTTTACGCCCACGGACGCACTGCATGTGACCGGTGCCCTGCAGCTGGGAG
ATGCCGGCGCATCGCTGCGGATGGCGCGGGCGCTGGCGGCGTTGCGGGGTGAAGATGCTGTGACCTTCAGCCGTAATGTT
CTTGAGCGGGCTGAAGCCCGTATTGAGGAGGCCATACTGCAGCATGTGGCCCGCCGAGAGGTCGGGGCGAATTTTGCGGG
ATTTCTGACACGGCGTCAGTCTTTTTCTCTGCTTGATGTTTCCGTACGGCTTGCGGTGCCCGTGGTGGGCATTGGCGCGG
CTGCACGGTATCTGGTGCCCGGGGTGGCCGCGCGGCTGGGAACCCGGGCTGTTTTTCCCGAACTGTATGAAGTGGGCAAC
GCCATGGGCGCGGCCGCGCTGGCGTTGCGCGGCATGTCGCCGTCATAA

Upstream 100 bases:

>100_bases
TGTCTATGCCTGACGGTTCAGCCATTGCCAAACCAAGGCAACGGGCGGTATCACAGCCGTCCGGAACCATCGGCGGACAG
CAGAAGACGGAGCGGGAATC

Downstream 100 bases:

>100_bases
GGAGCACGGAATGCCGTACAGACCGTTGTGTTTTGATGCAGCCATGGAAGTGGCCAGCGAAGTGGAAGAGTTCGGTGTGG
TACACGGGTGGGTAAGGCGC

Product: hydantoinase/oxoprolinase family protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MSDFTEQNRTAAPDGGFVIGVDAGGTYTDAVVVDIAGGHAVARAKRPTTHYQPSTGVAAAIGDVLLKAGINPADVRSTAV
STTLATNALLENKGVDVGLIVIGFNQRMEVPAAAARYVPGGHRQDGTEAEPLGLEFLLDHLKDLHGRVDAYAVCSLHSYA
NPAHELVAAEAIRLTSGLPVFCSHEVSMQAGMRERATTAVLNARLLPVMEQFLAGVRKALDEQGIRGTVQVVRGDASTMG
MEQAVRSAASTVASGPAATACFGAQYAATACCDYAGQQPQDVLVVDVGGTTTDMTIVHEGRPVIDTGGMLVGEWQTHVDA
VEMFTVAVGGDSLVELDPVGTLSLGPARVVPVCMAAAWGVELPDPALWAGPGLGGRCVCAGAGLEGDACSGDALLQLLCA
RRAMPLAELLAALSMAEVTYNGRMMRLARGQKIFECGFTPTDALHVTGALQLGDAGASLRMARALAALRGEDAVTFSRNV
LERAEARIEEAILQHVARREVGANFAGFLTRRQSFSLLDVSVRLAVPVVGIGAAARYLVPGVAARLGTRAVFPELYEVGN
AMGAAALALRGMSPS

Sequences:

>Translated_575_residues
MSDFTEQNRTAAPDGGFVIGVDAGGTYTDAVVVDIAGGHAVARAKRPTTHYQPSTGVAAAIGDVLLKAGINPADVRSTAV
STTLATNALLENKGVDVGLIVIGFNQRMEVPAAAARYVPGGHRQDGTEAEPLGLEFLLDHLKDLHGRVDAYAVCSLHSYA
NPAHELVAAEAIRLTSGLPVFCSHEVSMQAGMRERATTAVLNARLLPVMEQFLAGVRKALDEQGIRGTVQVVRGDASTMG
MEQAVRSAASTVASGPAATACFGAQYAATACCDYAGQQPQDVLVVDVGGTTTDMTIVHEGRPVIDTGGMLVGEWQTHVDA
VEMFTVAVGGDSLVELDPVGTLSLGPARVVPVCMAAAWGVELPDPALWAGPGLGGRCVCAGAGLEGDACSGDALLQLLCA
RRAMPLAELLAALSMAEVTYNGRMMRLARGQKIFECGFTPTDALHVTGALQLGDAGASLRMARALAALRGEDAVTFSRNV
LERAEARIEEAILQHVARREVGANFAGFLTRRQSFSLLDVSVRLAVPVVGIGAAARYLVPGVAARLGTRAVFPELYEVGN
AMGAAALALRGMSPS
>Mature_574_residues
SDFTEQNRTAAPDGGFVIGVDAGGTYTDAVVVDIAGGHAVARAKRPTTHYQPSTGVAAAIGDVLLKAGINPADVRSTAVS
TTLATNALLENKGVDVGLIVIGFNQRMEVPAAAARYVPGGHRQDGTEAEPLGLEFLLDHLKDLHGRVDAYAVCSLHSYAN
PAHELVAAEAIRLTSGLPVFCSHEVSMQAGMRERATTAVLNARLLPVMEQFLAGVRKALDEQGIRGTVQVVRGDASTMGM
EQAVRSAASTVASGPAATACFGAQYAATACCDYAGQQPQDVLVVDVGGTTTDMTIVHEGRPVIDTGGMLVGEWQTHVDAV
EMFTVAVGGDSLVELDPVGTLSLGPARVVPVCMAAAWGVELPDPALWAGPGLGGRCVCAGAGLEGDACSGDALLQLLCAR
RAMPLAELLAALSMAEVTYNGRMMRLARGQKIFECGFTPTDALHVTGALQLGDAGASLRMARALAALRGEDAVTFSRNVL
ERAEARIEEAILQHVARREVGANFAGFLTRRQSFSLLDVSVRLAVPVVGIGAAARYLVPGVAARLGTRAVFPELYEVGNA
MGAAALALRGMSPS

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 59662; Mature: 59531

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFTEQNRTAAPDGGFVIGVDAGGTYTDAVVVDIAGGHAVARAKRPTTHYQPSTGVAAA
CCCCCCCCCCCCCCCCEEEEECCCCCEECEEEEEECCCCEEHHCCCCCCCCCCCCCHHHH
IGDVLLKAGINPADVRSTAVSTTLATNALLENKGVDVGLIVIGFNQRMEVPAAAARYVPG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHCCCC
GHRQDGTEAEPLGLEFLLDHLKDLHGRVDAYAVCSLHSYANPAHELVAAEAIRLTSGLPV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHHHHHHHHHHCCCCCE
FCSHEVSMQAGMRERATTAVLNARLLPVMEQFLAGVRKALDEQGIRGTVQVVRGDASTMG
EECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
MEQAVRSAASTVASGPAATACFGAQYAATACCDYAGQQPQDVLVVDVGGTTTDMTIVHEG
HHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECC
RPVIDTGGMLVGEWQTHVDAVEMFTVAVGGDSLVELDPVGTLSLGPARVVPVCMAAAWGV
CCEEECCCEEEECHHHHHHHEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHCCC
ELPDPALWAGPGLGGRCVCAGAGLEGDACSGDALLQLLCARRAMPLAELLAALSMAEVTY
CCCCCCEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEE
NGRMMRLARGQKIFECGFTPTDALHVTGALQLGDAGASLRMARALAALRGEDAVTFSRNV
CCEEEEECCCCEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHH
LERAEARIEEAILQHVARREVGANFAGFLTRRQSFSLLDVSVRLAVPVVGIGAAARYLVP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEEEECEEECCHHHHHHHH
GVAARLGTRAVFPELYEVGNAMGAAALALRGMSPS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDFTEQNRTAAPDGGFVIGVDAGGTYTDAVVVDIAGGHAVARAKRPTTHYQPSTGVAAA
CCCCCCCCCCCCCCCEEEEECCCCCEECEEEEEECCCCEEHHCCCCCCCCCCCCCHHHH
IGDVLLKAGINPADVRSTAVSTTLATNALLENKGVDVGLIVIGFNQRMEVPAAAARYVPG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHCCCC
GHRQDGTEAEPLGLEFLLDHLKDLHGRVDAYAVCSLHSYANPAHELVAAEAIRLTSGLPV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHHHHHHHHHHCCCCCE
FCSHEVSMQAGMRERATTAVLNARLLPVMEQFLAGVRKALDEQGIRGTVQVVRGDASTMG
EECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHH
MEQAVRSAASTVASGPAATACFGAQYAATACCDYAGQQPQDVLVVDVGGTTTDMTIVHEG
HHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECC
RPVIDTGGMLVGEWQTHVDAVEMFTVAVGGDSLVELDPVGTLSLGPARVVPVCMAAAWGV
CCEEECCCEEEECHHHHHHHEEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHCCC
ELPDPALWAGPGLGGRCVCAGAGLEGDACSGDALLQLLCARRAMPLAELLAALSMAEVTY
CCCCCCEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEE
NGRMMRLARGQKIFECGFTPTDALHVTGALQLGDAGASLRMARALAALRGEDAVTFSRNV
CCEEEEECCCCEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHH
LERAEARIEEAILQHVARREVGANFAGFLTRRQSFSLLDVSVRLAVPVVGIGAAARYLVP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEEEECEEECCHHHHHHHH
GVAARLGTRAVFPELYEVGNAMGAAALALRGMSPS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]