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The map label for this gene is yqhD [H]

Identifier: 78355097

GI number: 78355097

Start: 39749

End: 40993

Strand: Direct

Name: yqhD [H]

Synonym: Dde_0050

Alternate gene names: 78355097

Gene position: 39749-40993 (Clockwise)

Preceding gene: 78355093

Following gene: 78355098

Centisome position: 1.07

GC content: 57.27

Gene sequence:

>1245_bases
ATGTTCCGGCATGGGCCGCTGGACGGGCCGTATGTGTCCGGCTGTGTCGTGCTGTCAGGCCGGTTTTCACAGGAGGTTTT
CAGCATGCTTGATTTTGATTTCCACAACCCTACCCGCATTGTTTTCGGCAAAGACAGACTGGCGGAGCTTGATACGCTGG
TTCCTGCCGGTGCCACTGTGCTTGTTCTGTACGGCGGGGGCAGTGTCCGCCGGTTCGGCACGCTGGACAAGGTGCGGGCT
GCCCTTGAAAACGGCAGAACCGTTCACGAGTTCGGCGGCATTGAACCCAACCCGCGGTACGAAACACTGCTGAAGGCGGT
GGAAAAGGTCCGCAGTGACGGTGTGGATTTTCTGCTGGCTGTGGGGGGCGGTTCCGTAATGGACGGGACAAAGTTTGTGT
CGCTGGCATCGGTGCATGACGGTGATCCTGAGTCGCTGCTGTACCACGGCTTTGCCGGTGTGCCCGCCGCAAAAGCTCTG
CCGCTGGGATGCGTGGTAACGCTGCCCGCCACCGGTTCTGAAATGAACATGGGAGGAGTTATCAGCAAGGGTGACGGAAA
GTTCCCCGTACTCTGCCCGCTTACCTTCCCGAAGTTTTCAATTCTTGATCCCACGCTTACCTACTCGCTGCCTGCCAGAC
AGGTGGCAAACGGAGTGGTGGACACCTTTGTCCATGTTATGGAGCAGTATCTCACCTTTCCCGTGGAAGGACGCTTTCAG
GACAGAACCTCGGAAGGCATCCTGCTGACCCTTATTGAAATCGGACGTTACACCATTGATCACCCCGAAGATTATGATGC
CCGTGCGAACCTTGTATGGTGCGCAACCATGGGGTTGAACGGCCTTATCGGTTCCGGGGTGCCGCAGGACTGGGCAACCC
ATATGATCGGGCACGAGATTACGTCTCTTTACGGGCTTGATCACGGCCAGACGCTGGCCATCATTTTGCCTGCCCTGATG
GATGTGCGCCGCGATGCCAAACGCGAAAAGCTGCTGCAGTATGCCGAGCGCATCTGGAACATCACCGGAGGCACAGACGA
TGAGCGCATTGATGCCGCCATTGCCCGGACAAGAGCCTTCTTTGAGTCTCTGGGCGTTAAAACCAGACTTTCCGACCATA
AGCTCGGCGTTGAGCATTTCGACGCTGTAATCAAGGGTCTGGAAGCAAAAGGACTGACAGCCATGTCCGAGCGCGGCGAC
CAGACGCTGGAAGTAAGCCGGAACGTTCTGAAGGCTGCCCTGTAG

Upstream 100 bases:

>100_bases
GCGCCGTGTCAGCGTATCTCCGGAGGGTGCGGGCATATGTTATGCGCGGGACGGGTGACGGGGCGCAGCCGATAGGATAC
AGTGGAGCGTTATCGTATAA

Downstream 100 bases:

>100_bases
CGTCCATCGGACAGGATGATTACGCATAGTAAACAGCCCGCCGGCCATGTGGCCTGCGGGCTGTTTTTTGTCCTTATGGG
GCTTTTTTCACAGCTATTGT

Product: alcohol dehydrogenase, iron-containing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MFRHGPLDGPYVSGCVVLSGRFSQEVFSMLDFDFHNPTRIVFGKDRLAELDTLVPAGATVLVLYGGGSVRRFGTLDKVRA
ALENGRTVHEFGGIEPNPRYETLLKAVEKVRSDGVDFLLAVGGGSVMDGTKFVSLASVHDGDPESLLYHGFAGVPAAKAL
PLGCVVTLPATGSEMNMGGVISKGDGKFPVLCPLTFPKFSILDPTLTYSLPARQVANGVVDTFVHVMEQYLTFPVEGRFQ
DRTSEGILLTLIEIGRYTIDHPEDYDARANLVWCATMGLNGLIGSGVPQDWATHMIGHEITSLYGLDHGQTLAIILPALM
DVRRDAKREKLLQYAERIWNITGGTDDERIDAAIARTRAFFESLGVKTRLSDHKLGVEHFDAVIKGLEAKGLTAMSERGD
QTLEVSRNVLKAAL

Sequences:

>Translated_414_residues
MFRHGPLDGPYVSGCVVLSGRFSQEVFSMLDFDFHNPTRIVFGKDRLAELDTLVPAGATVLVLYGGGSVRRFGTLDKVRA
ALENGRTVHEFGGIEPNPRYETLLKAVEKVRSDGVDFLLAVGGGSVMDGTKFVSLASVHDGDPESLLYHGFAGVPAAKAL
PLGCVVTLPATGSEMNMGGVISKGDGKFPVLCPLTFPKFSILDPTLTYSLPARQVANGVVDTFVHVMEQYLTFPVEGRFQ
DRTSEGILLTLIEIGRYTIDHPEDYDARANLVWCATMGLNGLIGSGVPQDWATHMIGHEITSLYGLDHGQTLAIILPALM
DVRRDAKREKLLQYAERIWNITGGTDDERIDAAIARTRAFFESLGVKTRLSDHKLGVEHFDAVIKGLEAKGLTAMSERGD
QTLEVSRNVLKAAL
>Mature_414_residues
MFRHGPLDGPYVSGCVVLSGRFSQEVFSMLDFDFHNPTRIVFGKDRLAELDTLVPAGATVLVLYGGGSVRRFGTLDKVRA
ALENGRTVHEFGGIEPNPRYETLLKAVEKVRSDGVDFLLAVGGGSVMDGTKFVSLASVHDGDPESLLYHGFAGVPAAKAL
PLGCVVTLPATGSEMNMGGVISKGDGKFPVLCPLTFPKFSILDPTLTYSLPARQVANGVVDTFVHVMEQYLTFPVEGRFQ
DRTSEGILLTLIEIGRYTIDHPEDYDARANLVWCATMGLNGLIGSGVPQDWATHMIGHEITSLYGLDHGQTLAIILPALM
DVRRDAKREKLLQYAERIWNITGGTDDERIDAAIARTRAFFESLGVKTRLSDHKLGVEHFDAVIKGLEAKGLTAMSERGD
QTLEVSRNVLKAAL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=390, Percent_Identity=58.4615384615385, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI48994951, Length=355, Percent_Identity=22.5352112676056, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082107, Length=288, Percent_Identity=26.0416666666667, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789163, Length=292, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321181, Length=302, Percent_Identity=22.1854304635762, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 44991; Mature: 44991

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRHGPLDGPYVSGCVVLSGRFSQEVFSMLDFDFHNPTRIVFGKDRLAELDTLVPAGATV
CCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCCEE
LVLYGGGSVRRFGTLDKVRAALENGRTVHEFGGIEPNPRYETLLKAVEKVRSDGVDFLLA
EEEECCCCCCHHCCHHHHHHHHHCCCEEHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
VGGGSVMDGTKFVSLASVHDGDPESLLYHGFAGVPAAKALPLGCVVTLPATGSEMNMGGV
ECCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCHHHCCCCCEEEECCCCCCCCCCCCE
ISKGDGKFPVLCPLTFPKFSILDPTLTYSLPARQVANGVVDTFVHVMEQYLTFPVEGRFQ
EECCCCCCEEEECCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DRTSEGILLTLIEIGRYTIDHPEDYDARANLVWCATMGLNGLIGSGVPQDWATHMIGHEI
CCCCCCEEEEEEHHCCEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
TSLYGLDHGQTLAIILPALMDVRRDAKREKLLQYAERIWNITGGTDDERIDAAIARTRAF
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
FESLGVKTRLSDHKLGVEHFDAVIKGLEAKGLTAMSERGDQTLEVSRNVLKAAL
HHHCCCEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFRHGPLDGPYVSGCVVLSGRFSQEVFSMLDFDFHNPTRIVFGKDRLAELDTLVPAGATV
CCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCCEE
LVLYGGGSVRRFGTLDKVRAALENGRTVHEFGGIEPNPRYETLLKAVEKVRSDGVDFLLA
EEEECCCCCCHHCCHHHHHHHHHCCCEEHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
VGGGSVMDGTKFVSLASVHDGDPESLLYHGFAGVPAAKALPLGCVVTLPATGSEMNMGGV
ECCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCHHHCCCCCEEEECCCCCCCCCCCCE
ISKGDGKFPVLCPLTFPKFSILDPTLTYSLPARQVANGVVDTFVHVMEQYLTFPVEGRFQ
EECCCCCCEEEECCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DRTSEGILLTLIEIGRYTIDHPEDYDARANLVWCATMGLNGLIGSGVPQDWATHMIGHEI
CCCCCCEEEEEEHHCCEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
TSLYGLDHGQTLAIILPALMDVRRDAKREKLLQYAERIWNITGGTDDERIDAAIARTRAF
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
FESLGVKTRLSDHKLGVEHFDAVIKGLEAKGLTAMSERGDQTLEVSRNVLKAAL
HHHCCCEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]