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The map label for this gene is secA

Identifier: 161485608

GI number: 161485608

Start: 1111357

End: 1113951

Strand: Reverse

Name: secA

Synonym: Dde_1082

Alternate gene names: 161485608

Gene position: 1113951-1111357 (Counterclockwise)

Preceding gene: 78356130

Following gene: 161485609

Centisome position: 29.86

GC content: 56.11

Gene sequence:

>2595_bases
ATGCTCGGTTCCATTGTCAAAAAAGTCTTCGGTTCCAAAAACGACCGTTATCTCAAATCGCTGAACCACTACCTGAAAGA
AATCAACGCGCTGGAAGAAAACATCGCCACCATGCCGGACGAGGCCATATCCGCCCGTATGGCCGAACTGCGCGCCGAAG
TGCAGCAGGGCACGTCACTTGACAGCATTCTGCCCGAGGTGTTTGCCATGGTGCGCGAAGCAGGCAAACGCGTGCTGGGA
ATGCGCCATTACGACGTGCAGATGGTCGGCGGCATAGCCCTGCATTCCGGCAAAATAGCCGAAATGCGTACCGGTGAAGG
TAAAACCCTTGTGGCCACGCTGCCCGCGGCTCTCAATGCGCTGACCGGCAAAGGTGTGCACCTGATCACCGTAAACGACT
ATCTGGCCCGCCGTGACGCCGAGTGGATGGGTAAAATCTACAATTTTCTCGGGCTCAGCGTGGGAGTCATAGTTCACGGG
CTTAACGATGAAGAACGCCGGGCGGCTTATGCCTCGGACATCACCTACGGCACAAACAACGAGTTCGGCTTCGATTACCT
GCGCGACAACATGAAGTTCTACAAAGAACAGCTTGTCCAGCGCCCCCATCATTTCGCCATTGTCGACGAAGTTGACTCCA
TTCTTATTGACGAAGCCCGTACGCCGCTGATCATTTCCGGCCCGTCCGATGAATCCACGGGGCTGTACCGCCGCGTCAAC
GACATCATTCCGCGCCTGAAACGCGATACACACTACACCGTGGACGAAAAGGCCCGCGCCGCGGCCCTGACCGATGAAGG
CGTGCAGGAAGCCGAAAAACTGCTCGGGCTGGACAACCTGTACGACCCGCAGAACATTTCCTTCCAGCACCACATTCTGC
AGGCGCTCAAGGCACACAGCATATTCACGCGCGATGTGGACTACATCGTAAAAGACGATCAGGTCGTCATTGTTGACGAA
TTCACCGGTCGACTGATGCCCGGACGCCGCTTTTCAGACGGACTGCATCAGGCGCTGGAGGCCAAGGAAGGCGTAAAGGT
GGAAGCCGAAAACCAGACGCTGGCATCCATCACCTTCCAGAACTACTTCCGCATGTATGAAAAACTGTCGGGCATGACAG
GCACGGCAGACACCGAAGCTGTGGAATTCCAGCAGATATATGATCTGGAAGTGGTCAATATTCCCACCAACAAACCCATG
ATACGTAAAGACCAGCCCGATTCCATATACAGAACGCGGCCTGAAAAATTCAACGCCATCGTGGAAGAAATAGCCAGACT
GCACCACAAGGGACAACCTGTGCTGGTGGGCACCATATCCATTGAAACATCCGAGCTTATCGCCGGCATGCTGAAGAAAA
AAGGCGTGCCGCACAATGTGCTGAACGCCAAACAACACGAAAAAGAAGCAGAAATCGTGGCAGAAGCAGGTCAGGCGGGC
AAAGTGACCATTGCCACCAACATGGCAGGCCGCGGTACCGACATAGTGCTGGGTGAAGGTGTGCCCCAGCTGGGCGGCCT
GTACATTCTGGGTACGGAACGCCACGAATCGCGGCGCATAGACAACCAGCTGCGCGGCCGTTCCGGCCGTCAGGGCGACC
CCGGCGAAACACGCTTTTTCCTTTCGCTGGAAGATGACCTGCTGCGTCTTTTCGGCTCTGACCGCATAGCCGGGCTTATG
GAAAGACTGGGCATGCAGGAAGGCGAACCCATCGAAAACAAAATGGTTTCGCGCGCCATAGAAAACGCCCAGAAACGTGT
CGAAGGACACAACTTTGAAATACGCAAGACCCTGCTCGATTATGACAACGTCATGAACCAGCAGCGCGAGGTCATATACA
GCCTGCGCCGCGATACCATGATGGAAGACGATCTTGAACCTTCGGTCCATGAGTTTCTCGACGATATCATCGAGGACATC
TACGCACCGCTGGAGCAGACCAAAGGCAAAGCCCTCGACGAAGAGACCCATGCGGCCATCGCCGCCCGGCTTGAAGAAAC
CTTTTTCCTTTCACGCGTGTACCCCGAATTCGCACTCAAGGGTTCGGAACAGCAGGAAAAGCTTCCGGAATTGCCTTCCG
CGGCAGATGTGAAGAAAGCGGTGGAAAGCATGCTGGAAAAACTCAAACGCGATGCAGGGCCGGTCTACGGCGACATCCTG
CGCTATTTCCTGCTTGAAGAGCTGGACCGCAACTGGAAAGAACACCTGCTGAACATGGACCACCTGCGCGACGGCATCGG
CCTGCGCGGGTACGGTCAGCGCGACCCCAAGCAGGAGTATAAGCGCGAAGGCTTTTCACTTTTCCAGAACATGCTCTGGA
GCATCAAGGAAAGCGTTTTCCGTGCGCTCACCCGCCTGCGGCTGCAGCGGGTGGAAGAAGCCGCCGATCCGGCAGAACAG
CCCGAAGCCGCGGGTCTGCAGGAAGCAAAAGCCACAGAACTGCGCCACAAAGAACAACCCGCCGAGCTGTCATATTCCGG
CGGTGATGAGGACGGCGCAAAAACCCCTTCGCGGCGCAACGCCCCGAAAGTCGGCCGTAATGATCCGTGCCCGTGCGGCA
GCGGCAAAAAATATAAAAAATGCTGCGGGGCCTGA

Upstream 100 bases:

>100_bases
TGTCCGGCAGCCGGCTGCCGCTGTGCTGTGTGCCCGTCACACAGACGTAACCAAAAGCGTGCACCATGCGCCGAATACAT
ACATCCGCCCGGGAGACAGA

Downstream 100 bases:

>100_bases
TCGCCCGACAAACACGACGGCAGACACACTGCCGACACATTCTGCCGGTATGCAGACACAACCGGCGCTCAGCGGTGCCG
GCGGCCGGTACAGCCAGCCG

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 864; Mature: 864

Protein sequence:

>864_residues
MLGSIVKKVFGSKNDRYLKSLNHYLKEINALEENIATMPDEAISARMAELRAEVQQGTSLDSILPEVFAMVREAGKRVLG
MRHYDVQMVGGIALHSGKIAEMRTGEGKTLVATLPAALNALTGKGVHLITVNDYLARRDAEWMGKIYNFLGLSVGVIVHG
LNDEERRAAYASDITYGTNNEFGFDYLRDNMKFYKEQLVQRPHHFAIVDEVDSILIDEARTPLIISGPSDESTGLYRRVN
DIIPRLKRDTHYTVDEKARAAALTDEGVQEAEKLLGLDNLYDPQNISFQHHILQALKAHSIFTRDVDYIVKDDQVVIVDE
FTGRLMPGRRFSDGLHQALEAKEGVKVEAENQTLASITFQNYFRMYEKLSGMTGTADTEAVEFQQIYDLEVVNIPTNKPM
IRKDQPDSIYRTRPEKFNAIVEEIARLHHKGQPVLVGTISIETSELIAGMLKKKGVPHNVLNAKQHEKEAEIVAEAGQAG
KVTIATNMAGRGTDIVLGEGVPQLGGLYILGTERHESRRIDNQLRGRSGRQGDPGETRFFLSLEDDLLRLFGSDRIAGLM
ERLGMQEGEPIENKMVSRAIENAQKRVEGHNFEIRKTLLDYDNVMNQQREVIYSLRRDTMMEDDLEPSVHEFLDDIIEDI
YAPLEQTKGKALDEETHAAIAARLEETFFLSRVYPEFALKGSEQQEKLPELPSAADVKKAVESMLEKLKRDAGPVYGDIL
RYFLLEELDRNWKEHLLNMDHLRDGIGLRGYGQRDPKQEYKREGFSLFQNMLWSIKESVFRALTRLRLQRVEEAADPAEQ
PEAAGLQEAKATELRHKEQPAELSYSGGDEDGAKTPSRRNAPKVGRNDPCPCGSGKKYKKCCGA

Sequences:

>Translated_864_residues
MLGSIVKKVFGSKNDRYLKSLNHYLKEINALEENIATMPDEAISARMAELRAEVQQGTSLDSILPEVFAMVREAGKRVLG
MRHYDVQMVGGIALHSGKIAEMRTGEGKTLVATLPAALNALTGKGVHLITVNDYLARRDAEWMGKIYNFLGLSVGVIVHG
LNDEERRAAYASDITYGTNNEFGFDYLRDNMKFYKEQLVQRPHHFAIVDEVDSILIDEARTPLIISGPSDESTGLYRRVN
DIIPRLKRDTHYTVDEKARAAALTDEGVQEAEKLLGLDNLYDPQNISFQHHILQALKAHSIFTRDVDYIVKDDQVVIVDE
FTGRLMPGRRFSDGLHQALEAKEGVKVEAENQTLASITFQNYFRMYEKLSGMTGTADTEAVEFQQIYDLEVVNIPTNKPM
IRKDQPDSIYRTRPEKFNAIVEEIARLHHKGQPVLVGTISIETSELIAGMLKKKGVPHNVLNAKQHEKEAEIVAEAGQAG
KVTIATNMAGRGTDIVLGEGVPQLGGLYILGTERHESRRIDNQLRGRSGRQGDPGETRFFLSLEDDLLRLFGSDRIAGLM
ERLGMQEGEPIENKMVSRAIENAQKRVEGHNFEIRKTLLDYDNVMNQQREVIYSLRRDTMMEDDLEPSVHEFLDDIIEDI
YAPLEQTKGKALDEETHAAIAARLEETFFLSRVYPEFALKGSEQQEKLPELPSAADVKKAVESMLEKLKRDAGPVYGDIL
RYFLLEELDRNWKEHLLNMDHLRDGIGLRGYGQRDPKQEYKREGFSLFQNMLWSIKESVFRALTRLRLQRVEEAADPAEQ
PEAAGLQEAKATELRHKEQPAELSYSGGDEDGAKTPSRRNAPKVGRNDPCPCGSGKKYKKCCGA
>Mature_864_residues
MLGSIVKKVFGSKNDRYLKSLNHYLKEINALEENIATMPDEAISARMAELRAEVQQGTSLDSILPEVFAMVREAGKRVLG
MRHYDVQMVGGIALHSGKIAEMRTGEGKTLVATLPAALNALTGKGVHLITVNDYLARRDAEWMGKIYNFLGLSVGVIVHG
LNDEERRAAYASDITYGTNNEFGFDYLRDNMKFYKEQLVQRPHHFAIVDEVDSILIDEARTPLIISGPSDESTGLYRRVN
DIIPRLKRDTHYTVDEKARAAALTDEGVQEAEKLLGLDNLYDPQNISFQHHILQALKAHSIFTRDVDYIVKDDQVVIVDE
FTGRLMPGRRFSDGLHQALEAKEGVKVEAENQTLASITFQNYFRMYEKLSGMTGTADTEAVEFQQIYDLEVVNIPTNKPM
IRKDQPDSIYRTRPEKFNAIVEEIARLHHKGQPVLVGTISIETSELIAGMLKKKGVPHNVLNAKQHEKEAEIVAEAGQAG
KVTIATNMAGRGTDIVLGEGVPQLGGLYILGTERHESRRIDNQLRGRSGRQGDPGETRFFLSLEDDLLRLFGSDRIAGLM
ERLGMQEGEPIENKMVSRAIENAQKRVEGHNFEIRKTLLDYDNVMNQQREVIYSLRRDTMMEDDLEPSVHEFLDDIIEDI
YAPLEQTKGKALDEETHAAIAARLEETFFLSRVYPEFALKGSEQQEKLPELPSAADVKKAVESMLEKLKRDAGPVYGDIL
RYFLLEELDRNWKEHLLNMDHLRDGIGLRGYGQRDPKQEYKREGFSLFQNMLWSIKESVFRALTRLRLQRVEEAADPAEQ
PEAAGLQEAKATELRHKEQPAELSYSGGDEDGAKTPSRRNAPKVGRNDPCPCGSGKKYKKCCGA

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=918, Percent_Identity=51.6339869281046, Blast_Score=905, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_DESDG (Q313L3)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387578.2
- HSSP:   P10408
- ProteinModelPortal:   Q313L3
- SMR:   Q313L3
- STRING:   Q313L3
- GeneID:   3755431
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1082
- NMPDR:   fig|207559.3.peg.911
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- ProtClustDB:   PRK12904
- BioCyc:   DDES207559:DDE_1082-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 97329; Mature: 97329

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGSIVKKVFGSKNDRYLKSLNHYLKEINALEENIATMPDEAISARMAELRAEVQQGTSL
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
DSILPEVFAMVREAGKRVLGMRHYDVQMVGGIALHSGKIAEMRTGEGKTLVATLPAALNA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCEEEEECCCCCEEEEEHHHHHHH
LTGKGVHLITVNDYLARRDAEWMGKIYNFLGLSVGVIVHGLNDEERRAAYASDITYGTNN
HCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCC
EFGFDYLRDNMKFYKEQLVQRPHHFAIVDEVDSILIDEARTPLIISGPSDESTGLYRRVN
CCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
DIIPRLKRDTHYTVDEKARAAALTDEGVQEAEKLLGLDNLYDPQNISFQHHILQALKAHS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
IFTRDVDYIVKDDQVVIVDEFTGRLMPGRRFSDGLHQALEAKEGVKVEAENQTLASITFQ
HHHHCCHHEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHH
NYFRMYEKLSGMTGTADTEAVEFQQIYDLEVVNIPTNKPMIRKDQPDSIYRTRPEKFNAI
HHHHHHHHHCCCCCCCCCHHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHH
VEEIARLHHKGQPVLVGTISIETSELIAGMLKKKGVPHNVLNAKQHEKEAEIVAEAGQAG
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCC
KVTIATNMAGRGTDIVLGEGVPQLGGLYILGTERHESRRIDNQLRGRSGRQGDPGETRFF
EEEEEECCCCCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEE
LSLEDDLLRLFGSDRIAGLMERLGMQEGEPIENKMVSRAIENAQKRVEGHNFEIRKTLLD
EECHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YDNVMNQQREVIYSLRRDTMMEDDLEPSVHEFLDDIIEDIYAPLEQTKGKALDEETHAAI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AARLEETFFLSRVYPEFALKGSEQQEKLPELPSAADVKKAVESMLEKLKRDAGPVYGDIL
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
RYFLLEELDRNWKEHLLNMDHLRDGIGLRGYGQRDPKQEYKREGFSLFQNMLWSIKESVF
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RALTRLRLQRVEEAADPAEQPEAAGLQEAKATELRHKEQPAELSYSGGDEDGAKTPSRRN
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
APKVGRNDPCPCGSGKKYKKCCGA
CCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MLGSIVKKVFGSKNDRYLKSLNHYLKEINALEENIATMPDEAISARMAELRAEVQQGTSL
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
DSILPEVFAMVREAGKRVLGMRHYDVQMVGGIALHSGKIAEMRTGEGKTLVATLPAALNA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCEEEEECCCCCEEEEEHHHHHHH
LTGKGVHLITVNDYLARRDAEWMGKIYNFLGLSVGVIVHGLNDEERRAAYASDITYGTNN
HCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCC
EFGFDYLRDNMKFYKEQLVQRPHHFAIVDEVDSILIDEARTPLIISGPSDESTGLYRRVN
CCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
DIIPRLKRDTHYTVDEKARAAALTDEGVQEAEKLLGLDNLYDPQNISFQHHILQALKAHS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
IFTRDVDYIVKDDQVVIVDEFTGRLMPGRRFSDGLHQALEAKEGVKVEAENQTLASITFQ
HHHHCCHHEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHH
NYFRMYEKLSGMTGTADTEAVEFQQIYDLEVVNIPTNKPMIRKDQPDSIYRTRPEKFNAI
HHHHHHHHHCCCCCCCCCHHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHH
VEEIARLHHKGQPVLVGTISIETSELIAGMLKKKGVPHNVLNAKQHEKEAEIVAEAGQAG
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCC
KVTIATNMAGRGTDIVLGEGVPQLGGLYILGTERHESRRIDNQLRGRSGRQGDPGETRFF
EEEEEECCCCCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEE
LSLEDDLLRLFGSDRIAGLMERLGMQEGEPIENKMVSRAIENAQKRVEGHNFEIRKTLLD
EECHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
YDNVMNQQREVIYSLRRDTMMEDDLEPSVHEFLDDIIEDIYAPLEQTKGKALDEETHAAI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AARLEETFFLSRVYPEFALKGSEQQEKLPELPSAADVKKAVESMLEKLKRDAGPVYGDIL
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
RYFLLEELDRNWKEHLLNMDHLRDGIGLRGYGQRDPKQEYKREGFSLFQNMLWSIKESVF
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RALTRLRLQRVEEAADPAEQPEAAGLQEAKATELRHKEQPAELSYSGGDEDGAKTPSRRN
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
APKVGRNDPCPCGSGKKYKKCCGA
CCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA