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The map label for this gene is czcB [H]

Identifier: 78224691

GI number: 78224691

Start: 3938179

End: 3939453

Strand: Direct

Name: czcB [H]

Synonym: Gmet_3508

Alternate gene names: 78224691

Gene position: 3938179-3939453 (Clockwise)

Preceding gene: 78224690

Following gene: 78224692

Centisome position: 98.52

GC content: 62.75

Gene sequence:

>1275_bases
GTGAACAGGAAAAACGGAATCATAATCGGCATCATCCTGGCCATGGCCGTCGGCGGTGCCTTTGTCTATCGCTCTACCCA
TGTGAAAGGGGGCGCCGGCGAGCACGCCGAAACGAAGGAGGCCGGCCATACGGATGAAAAGGGAGGCCACGAAGAGGGGA
AGCACGAGGGAGAGAAGGAAGGTCATGAAGGCCATGATGAGCATGGGGAAGAAGGGACGATCAAGATGACCGCCGAGGTG
CAGAAGCAGAACGGCGTGGCCGTTGCTCCGGCCCAAAAACAGCGGCTCGCCGGCGCGATCAGCGCCACCGGCAAGGTGGA
GGCCAATGCCGACCGGATCGCCCATGTCTCGCCGCGCATCTCCGGCAAGATCGTCAGCGTCCGGGCCTCCCTCGGAGACG
GCGTCGCCGCCGGGCAGCCCCTGGTGACCCTGGACAGCGTCGAACTGGGTGAGGCCCTGAACCGCTACCACCAGTCAAAG
ACACGGCTCGCCCTGGCCCAGTCCAATATGGACCGGATCAAGGCGCTGGTGGAGAAGAAGATTGCAGCCCGCAAGGACAT
CCTCCAGGCGGAGACCGACTACAAGATGGCGCAGACGGAACTCCATACCGATGAAGAACGCCTCTCCCTCTATGGCGTTT
CAACCTCTGACCTCGGAAAGGCAAACCACCGGAAGCCGCTCCTGCCGGTCCGCTCCCCCATCGGCGGCATCATCACCGAA
AAACACGCCATCGTCGGCGAGCTGGCCGACCCATCCAAGAGCCTCTACACCGTGGCTGACCTTTCGTCGGTCTGGGTGAT
GGTGGACATCAACGAAAAAGATCTGGTCAAGATTCACCGGGGGCAGACTGCCGCCGTCACCGTCAGCGCCTTTCCCGACC
TGAAACTGAAGGGGCGGATCACCTACATCGCCGACCTGGTTGACGAATCAACCCGCACGGTCAAGGCCCGGGTCGAGGTG
GCCAATCCGGGGCGGAAGCTGAAGCCGGAGATGTTCGCCACTATTGAGTTGACGCTGGCGGCCGACGCGCCGCCGGTCCT
GGCCGTCCCCGAGGATGCCCTGCAGGACCTGGACGGGAAAAAGGTGCTCTTCATCGCGGAGAAGGACTCCGAATTCGCTG
CCCGTCCCGTGCAGACCGGCCGGGCGGCCGGCGGTCTGGTGGAGATCGTTTCCGGTCTGAAGGAGGGTGAGAACTACGCC
GTCAAGGGCTCGTTCATCCTCAAGTCGGAGATCAAGAAGGGTGAGATGACCGACGAGCACGGCCACGGCAAATGA

Upstream 100 bases:

>100_bases
ACGGCTACCTCGCCGCCCTTGCCGACCGGCAGACCGCCCTGGCGCGGCTCGAAGCCTCGGTGGGGGTCGATTTCCAGAAC
AAGACCAGCGGAGGTGCGCA

Downstream 100 bases:

>100_bases
TAATACCCTCTCCCTATGGGAGAGGGCTAGGGTGAGGGGGATATGTTGCTGCCTCCCTGTTTTCCCCTCATCCGGCCTTC
GGCCACCTTCTCCCATGGGG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MNRKNGIIIGIILAMAVGGAFVYRSTHVKGGAGEHAETKEAGHTDEKGGHEEGKHEGEKEGHEGHDEHGEEGTIKMTAEV
QKQNGVAVAPAQKQRLAGAISATGKVEANADRIAHVSPRISGKIVSVRASLGDGVAAGQPLVTLDSVELGEALNRYHQSK
TRLALAQSNMDRIKALVEKKIAARKDILQAETDYKMAQTELHTDEERLSLYGVSTSDLGKANHRKPLLPVRSPIGGIITE
KHAIVGELADPSKSLYTVADLSSVWVMVDINEKDLVKIHRGQTAAVTVSAFPDLKLKGRITYIADLVDESTRTVKARVEV
ANPGRKLKPEMFATIELTLAADAPPVLAVPEDALQDLDGKKVLFIAEKDSEFAARPVQTGRAAGGLVEIVSGLKEGENYA
VKGSFILKSEIKKGEMTDEHGHGK

Sequences:

>Translated_424_residues
MNRKNGIIIGIILAMAVGGAFVYRSTHVKGGAGEHAETKEAGHTDEKGGHEEGKHEGEKEGHEGHDEHGEEGTIKMTAEV
QKQNGVAVAPAQKQRLAGAISATGKVEANADRIAHVSPRISGKIVSVRASLGDGVAAGQPLVTLDSVELGEALNRYHQSK
TRLALAQSNMDRIKALVEKKIAARKDILQAETDYKMAQTELHTDEERLSLYGVSTSDLGKANHRKPLLPVRSPIGGIITE
KHAIVGELADPSKSLYTVADLSSVWVMVDINEKDLVKIHRGQTAAVTVSAFPDLKLKGRITYIADLVDESTRTVKARVEV
ANPGRKLKPEMFATIELTLAADAPPVLAVPEDALQDLDGKKVLFIAEKDSEFAARPVQTGRAAGGLVEIVSGLKEGENYA
VKGSFILKSEIKKGEMTDEHGHGK
>Mature_424_residues
MNRKNGIIIGIILAMAVGGAFVYRSTHVKGGAGEHAETKEAGHTDEKGGHEEGKHEGEKEGHEGHDEHGEEGTIKMTAEV
QKQNGVAVAPAQKQRLAGAISATGKVEANADRIAHVSPRISGKIVSVRASLGDGVAAGQPLVTLDSVELGEALNRYHQSK
TRLALAQSNMDRIKALVEKKIAARKDILQAETDYKMAQTELHTDEERLSLYGVSTSDLGKANHRKPLLPVRSPIGGIITE
KHAIVGELADPSKSLYTVADLSSVWVMVDINEKDLVKIHRGQTAAVTVSAFPDLKLKGRITYIADLVDESTRTVKARVEV
ANPGRKLKPEMFATIELTLAADAPPVLAVPEDALQDLDGKKVLFIAEKDSEFAARPVQTGRAAGGLVEIVSGLKEGENYA
VKGSFILKSEIKKGEMTDEHGHGK

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=335, Percent_Identity=28.0597014925373, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081796, Length=325, Percent_Identity=25.5384615384615, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789929, Length=310, Percent_Identity=26.7741935483871, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789665, Length=317, Percent_Identity=25.8675078864353, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 45398; Mature: 45398

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKNGIIIGIILAMAVGGAFVYRSTHVKGGAGEHAETKEAGHTDEKGGHEEGKHEGEKE
CCCCCCEEHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GHEGHDEHGEEGTIKMTAEVQKQNGVAVAPAQKQRLAGAISATGKVEANADRIAHVSPRI
CCCCCCCCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHCCCCEEECCCCCEEECCCCC
SGKIVSVRASLGDGVAAGQPLVTLDSVELGEALNRYHQSKTRLALAQSNMDRIKALVEKK
CCEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IAARKDILQAETDYKMAQTELHTDEERLSLYGVSTSDLGKANHRKPLLPVRSPIGGIITE
HHHHHHHHHCCCCCHHHHHHHCCCHHHEEEEECCHHHCCCCCCCCCCCCCCCCCCCHHCC
KHAIVGELADPSKSLYTVADLSSVWVMVDINEKDLVKIHRGQTAAVTVSAFPDLKLKGRI
CHHHEECCCCCCCCEEEEEECCEEEEEEECCCCCEEEEECCCEEEEEEECCCCEEECCEE
TYIADLVDESTRTVKARVEVANPGRKLKPEMFATIELTLAADAPPVLAVPEDALQDLDGK
EEEHHHHCCCCEEEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCEEECCHHHHHCCCCC
KVLFIAEKDSEFAARPVQTGRAAGGLVEIVSGLKEGENYAVKGSFILKSEIKKGEMTDEH
EEEEEEECCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCC
GHGK
CCCC
>Mature Secondary Structure
MNRKNGIIIGIILAMAVGGAFVYRSTHVKGGAGEHAETKEAGHTDEKGGHEEGKHEGEKE
CCCCCCEEHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GHEGHDEHGEEGTIKMTAEVQKQNGVAVAPAQKQRLAGAISATGKVEANADRIAHVSPRI
CCCCCCCCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHCCCCEEECCCCCEEECCCCC
SGKIVSVRASLGDGVAAGQPLVTLDSVELGEALNRYHQSKTRLALAQSNMDRIKALVEKK
CCEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IAARKDILQAETDYKMAQTELHTDEERLSLYGVSTSDLGKANHRKPLLPVRSPIGGIITE
HHHHHHHHHCCCCCHHHHHHHCCCHHHEEEEECCHHHCCCCCCCCCCCCCCCCCCCHHCC
KHAIVGELADPSKSLYTVADLSSVWVMVDINEKDLVKIHRGQTAAVTVSAFPDLKLKGRI
CHHHEECCCCCCCCEEEEEECCEEEEEEECCCCCEEEEECCCEEEEEEECCCCEEECCEE
TYIADLVDESTRTVKARVEVANPGRKLKPEMFATIELTLAADAPPVLAVPEDALQDLDGK
EEEHHHHCCCCEEEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCEEECCHHHHHCCCCC
KVLFIAEKDSEFAARPVQTGRAAGGLVEIVSGLKEGENYAVKGSFILKSEIKKGEMTDEH
EEEEEEECCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCC
GHGK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]