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The map label for this gene is eryC1 [H]

Identifier: 78222538

GI number: 78222538

Start: 1481248

End: 1482354

Strand: Direct

Name: eryC1 [H]

Synonym: Gmet_1325

Alternate gene names: 78222538

Gene position: 1481248-1482354 (Clockwise)

Preceding gene: 78222537

Following gene: 78222539

Centisome position: 37.06

GC content: 46.07

Gene sequence:

>1107_bases
ATGATTATTCCCTTCCTCGATCTAAAATCCCCCTATCTTGAACTGCAAGCAGAGCTGGACGATGCCTATCGGCGTGTCAT
GGAATCGGGGTGGTACATACTAGGCAAAGAGGTTGAAGCGTTCGAGGCAGAGTTTGCAGAGTACTGTCAGGTTAAGCACT
GTATCGGTGTGGGGAATGGCCTTGAAGCCCTACATCTTATTCTGCGGGCCATGGATATCGGACCAGGCGATGAAGTCATT
GTTCCATCCAACACCTATATTGCAACATGGCTTGCCGTCTCATATACGGGCGCCACTCCGGTACCAGTTGAACCAGATGT
AATTACATATAATCTCAACCCGGTCTTGATTGAAGTAGCAATAACTAAAAACACCAAGGCGATACTTCCGGTCCACCTTT
ACGGCCAAACCGCCGATATGGATCCGATAAATGCGATTGCTGCTCGGTACGGCCTTAAGGTTGTAGAAGATGTTGCACAA
TCACATGGCGCACGCTACAAGGGTCGACGCGCCGGTTCATTGGGTGACGCAGCCGGGTTCAGTTTCTACCCCGGGAAAAA
CATGGGCGCCTTTGGTGATGGCGGCGCGATCACCACAAATGATGATCAATTAGCAAAAAAAATACGGGTGTTGCGCAACT
ATGGTTCACAAATAAAATATCATAATGAGATCAAAGGTTATAATTCACGACTTGATGAACTGCAGGCAGCATTTTTGAGA
GTGAAGTTGACAAAACTGGACGAATGGAATGAAAGGCGTAAGCAGATTGCTGCTAGTTATCTGGATGGTTTGAAATCGAA
TGAGCATCTTGTTTTGCCACATGTTCCTGAATGGGCGGATCCTGTCTGGCACCTCTTTGTATTAAGGTGCAAAAATAGGG
ATGTTTTGCAAAGACAGTTAAACGAAGCAGGAATCGGCACGATGATTCACTATCCGATCCCTCCGCATCTTCAGCCAGCG
TATTCAGAGCTTGGTTTCTCTGAAGGAACATTTCCAATTTCGGAAAACATTCATGTTGAGGTGCTTAGCCTTCCAATGGG
ACCGTCGATGTCAAAAGCACAAGCGGAATTTGTTATAAAAACAATGAATCGGATTTTAATACCTTGA

Upstream 100 bases:

>100_bases
AATATTCTCCAGATGCAGTTCTGATGGTGCTTGCTTCGGATGTCTACAAACCTGAAGATTACATTAGGGATTATGACCAG
TTTATTGCCTTGGTGAAGAA

Downstream 100 bases:

>100_bases
ATCTCATCAAAACAAGTCTGCTCAATGGTATTGCTGTTGTAATTAGATTGTTTACTTCTATTGGCCTGAACAAGGTTCTT
GCATTATATGTGGGGCCTGC

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MIIPFLDLKSPYLELQAELDDAYRRVMESGWYILGKEVEAFEAEFAEYCQVKHCIGVGNGLEALHLILRAMDIGPGDEVI
VPSNTYIATWLAVSYTGATPVPVEPDVITYNLNPVLIEVAITKNTKAILPVHLYGQTADMDPINAIAARYGLKVVEDVAQ
SHGARYKGRRAGSLGDAAGFSFYPGKNMGAFGDGGAITTNDDQLAKKIRVLRNYGSQIKYHNEIKGYNSRLDELQAAFLR
VKLTKLDEWNERRKQIAASYLDGLKSNEHLVLPHVPEWADPVWHLFVLRCKNRDVLQRQLNEAGIGTMIHYPIPPHLQPA
YSELGFSEGTFPISENIHVEVLSLPMGPSMSKAQAEFVIKTMNRILIP

Sequences:

>Translated_368_residues
MIIPFLDLKSPYLELQAELDDAYRRVMESGWYILGKEVEAFEAEFAEYCQVKHCIGVGNGLEALHLILRAMDIGPGDEVI
VPSNTYIATWLAVSYTGATPVPVEPDVITYNLNPVLIEVAITKNTKAILPVHLYGQTADMDPINAIAARYGLKVVEDVAQ
SHGARYKGRRAGSLGDAAGFSFYPGKNMGAFGDGGAITTNDDQLAKKIRVLRNYGSQIKYHNEIKGYNSRLDELQAAFLR
VKLTKLDEWNERRKQIAASYLDGLKSNEHLVLPHVPEWADPVWHLFVLRCKNRDVLQRQLNEAGIGTMIHYPIPPHLQPA
YSELGFSEGTFPISENIHVEVLSLPMGPSMSKAQAEFVIKTMNRILIP
>Mature_368_residues
MIIPFLDLKSPYLELQAELDDAYRRVMESGWYILGKEVEAFEAEFAEYCQVKHCIGVGNGLEALHLILRAMDIGPGDEVI
VPSNTYIATWLAVSYTGATPVPVEPDVITYNLNPVLIEVAITKNTKAILPVHLYGQTADMDPINAIAARYGLKVVEDVAQ
SHGARYKGRRAGSLGDAAGFSFYPGKNMGAFGDGGAITTNDDQLAKKIRVLRNYGSQIKYHNEIKGYNSRLDELQAAFLR
VKLTKLDEWNERRKQIAASYLDGLKSNEHLVLPHVPEWADPVWHLFVLRCKNRDVLQRQLNEAGIGTMIHYPIPPHLQPA
YSELGFSEGTFPISENIHVEVLSLPMGPSMSKAQAEFVIKTMNRILIP

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=380, Percent_Identity=36.5789473684211, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI2367285, Length=315, Percent_Identity=33.6507936507937, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 41004; Mature: 41004

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIPFLDLKSPYLELQAELDDAYRRVMESGWYILGKEVEAFEAEFAEYCQVKHCIGVGNG
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCC
LEALHLILRAMDIGPGDEVIVPSNTYIATWLAVSYTGATPVPVEPDVITYNLNPVLIEVA
HHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEEEECCCCCCCCCCCEEEEECCEEEEEEE
ITKNTKAILPVHLYGQTADMDPINAIAARYGLKVVEDVAQSHGARYKGRRAGSLGDAAGF
EECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SFYPGKNMGAFGDGGAITTNDDQLAKKIRVLRNYGSQIKYHNEIKGYNSRLDELQAAFLR
CCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEECHHHCCHHHHHHHHHHHHHH
VKLTKLDEWNERRKQIAASYLDGLKSNEHLVLPHVPEWADPVWHLFVLRCKNRDVLQRQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHEEHHHEECCHHHHHHHH
NEAGIGTMIHYPIPPHLQPAYSELGFSEGTFPISENIHVEVLSLPMGPSMSKAQAEFVIK
HHCCCCEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
TMNRILIP
HHHHHCCC
>Mature Secondary Structure
MIIPFLDLKSPYLELQAELDDAYRRVMESGWYILGKEVEAFEAEFAEYCQVKHCIGVGNG
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCC
LEALHLILRAMDIGPGDEVIVPSNTYIATWLAVSYTGATPVPVEPDVITYNLNPVLIEVA
HHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEEEECCCCCCCCCCCEEEEECCEEEEEEE
ITKNTKAILPVHLYGQTADMDPINAIAARYGLKVVEDVAQSHGARYKGRRAGSLGDAAGF
EECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SFYPGKNMGAFGDGGAITTNDDQLAKKIRVLRNYGSQIKYHNEIKGYNSRLDELQAAFLR
CCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEECHHHCCHHHHHHHHHHHHHH
VKLTKLDEWNERRKQIAASYLDGLKSNEHLVLPHVPEWADPVWHLFVLRCKNRDVLQRQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHEEHHHEECCHHHHHHHH
NEAGIGTMIHYPIPPHLQPAYSELGFSEGTFPISENIHVEVLSLPMGPSMSKAQAEFVIK
HHCCCCEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
TMNRILIP
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]