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The map label for this gene is gcp

Identifier: 78222517

GI number: 78222517

Start: 1465823

End: 1466848

Strand: Direct

Name: gcp

Synonym: Gmet_1303

Alternate gene names: 78222517

Gene position: 1465823-1466848 (Clockwise)

Preceding gene: 78222516

Following gene: 78222518

Centisome position: 36.67

GC content: 65.5

Gene sequence:

>1026_bases
ATGCTCATTCTCACGATCGAAACATCCTGCGACGAAACCGCCGCCGCGGTGGTCCGCGACGGGCGCACGGTGCTGTCGAG
CATCGTTGCGACCCAGGTGAAGGACCATGCCGTCTACGGGGGGGTTGTCCCTGAGATAGCCTCCCGCAAACATCTGGAGA
GCATCCCGGTCGTCATCGACGAAGCCCTCCGCACTGCTTCGGTCTCCCTCGACGCCATCGAGGGGGTCGCCGTGACCCAG
GGGCCGGGACTGGCCGGGGCACTTCTGGTGGGTACCGCCGTTGCCAAGGCCATCGCCTTTGCCCGCCGGCTCCCCATCGT
TGGGGTGAACCATATCGAAGGGCACCTCTCGGCCATTTTCCTGGAGCGAGAGGTGGCGTTTCCCTTCGTGGCCCTCGCCG
TCTCGGGGGGGCATACCCATCTCTACCGGGTCGACGGCATCGGCCGCTACACCACCCTCGGCCAGACCCGCGACGACGCT
GCCGGCGAGGCCTTCGACAAAGTCGCAAAGCTCTTGGGACTCCCCTATCCGGGCGGGGTTGAGATCGATCGCCTTGCCGC
CGAGGGGGACCCAGCCAGCATTTCCTTCCCCCGGCCGCTCCTCCACGACGGCAGCTTCAACTTCAGCTTCAGCGGCCTCA
AGACTGCGGTTCTGAACCATGTCCGCAAGAATCCGGTCCAGGAGGATGGCCAGCAACTCCGGGACCTCTGCGCTTCGTTT
CAACGGGCCGCCTGCGACGTGCTCGTGACGAAAACGCTCCTTGCCGCAGAGACCGAGGGGATCGGTCGGGTCGTGGTTGC
CGGCGGCGTTGCCTGCAATAGCGCCCTGCGCCGCGACATGGCCCGGGAGGCTGCTGACAGGGGAATCGAGCTCGCCATCC
CTTCTCCTTCCCTCTGTAGCGATAACGCCGCCATGCTGGCGGTTCCCGGTGATTTCTACCTCTCCCGGGGGATCAGCGAC
GGCCTCTCCCTGGACGCCTTGGTAAACTGGCCCTTGGATACGATCCGGACGAGGCTGGAGTCGTGA

Upstream 100 bases:

>100_bases
ACGTGGTGGAGCGCTTCAAGGAGCAGGCAATCGCCGGCCATGTCACCATGACCAAGGGCGAGCGCTCCGACCTGGCGGAA
CTGGCGGCGAATCTGCTGTA

Downstream 100 bases:

>100_bases
GAGGGGAGGGGATTCGCGCCCGCAAGGCGCTGGGGCAGAATTTTCTCGTGGACCGTCATGTTCTCGCACGGATCGCGGAC
ATCGTCGATATGCGGCCCGA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MLILTIETSCDETAAAVVRDGRTVLSSIVATQVKDHAVYGGVVPEIASRKHLESIPVVIDEALRTASVSLDAIEGVAVTQ
GPGLAGALLVGTAVAKAIAFARRLPIVGVNHIEGHLSAIFLEREVAFPFVALAVSGGHTHLYRVDGIGRYTTLGQTRDDA
AGEAFDKVAKLLGLPYPGGVEIDRLAAEGDPASISFPRPLLHDGSFNFSFSGLKTAVLNHVRKNPVQEDGQQLRDLCASF
QRAACDVLVTKTLLAAETEGIGRVVVAGGVACNSALRRDMAREAADRGIELAIPSPSLCSDNAAMLAVPGDFYLSRGISD
GLSLDALVNWPLDTIRTRLES

Sequences:

>Translated_341_residues
MLILTIETSCDETAAAVVRDGRTVLSSIVATQVKDHAVYGGVVPEIASRKHLESIPVVIDEALRTASVSLDAIEGVAVTQ
GPGLAGALLVGTAVAKAIAFARRLPIVGVNHIEGHLSAIFLEREVAFPFVALAVSGGHTHLYRVDGIGRYTTLGQTRDDA
AGEAFDKVAKLLGLPYPGGVEIDRLAAEGDPASISFPRPLLHDGSFNFSFSGLKTAVLNHVRKNPVQEDGQQLRDLCASF
QRAACDVLVTKTLLAAETEGIGRVVVAGGVACNSALRRDMAREAADRGIELAIPSPSLCSDNAAMLAVPGDFYLSRGISD
GLSLDALVNWPLDTIRTRLES
>Mature_341_residues
MLILTIETSCDETAAAVVRDGRTVLSSIVATQVKDHAVYGGVVPEIASRKHLESIPVVIDEALRTASVSLDAIEGVAVTQ
GPGLAGALLVGTAVAKAIAFARRLPIVGVNHIEGHLSAIFLEREVAFPFVALAVSGGHTHLYRVDGIGRYTTLGQTRDDA
AGEAFDKVAKLLGLPYPGGVEIDRLAAEGDPASISFPRPLLHDGSFNFSFSGLKTAVLNHVRKNPVQEDGQQLRDLCASF
QRAACDVLVTKTLLAAETEGIGRVVVAGGVACNSALRRDMAREAADRGIELAIPSPSLCSDNAAMLAVPGDFYLSRGISD
GLSLDALVNWPLDTIRTRLES

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=338, Percent_Identity=34.0236686390533, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI8923380, Length=311, Percent_Identity=31.1897106109325, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1789445, Length=333, Percent_Identity=45.945945945946, Blast_Score=276, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17557464, Length=331, Percent_Identity=32.3262839879154, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=322, Percent_Identity=31.055900621118, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320099, Length=365, Percent_Identity=29.5890410958904, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6322891, Length=291, Percent_Identity=29.553264604811, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129063, Length=334, Percent_Identity=34.1317365269461, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21357207, Length=320, Percent_Identity=30.3125, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_GEOMG (Q39W35)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384264.1
- ProteinModelPortal:   Q39W35
- SMR:   Q39W35
- STRING:   Q39W35
- MEROPS:   M22.001
- GeneID:   3739472
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1303
- NMPDR:   fig|269799.3.peg.826
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q39W35
- ProtClustDB:   PRK09604
- BioCyc:   GMET269799:GMET_1303-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35882; Mature: 35882

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILTIETSCDETAAAVVRDGRTVLSSIVATQVKDHAVYGGVVPEIASRKHLESIPVVID
CEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHH
EALRTASVSLDAIEGVAVTQGPGLAGALLVGTAVAKAIAFARRLPIVGVNHIEGHLSAIF
HHHHHHHCCHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHE
LEREVAFPFVALAVSGGHTHLYRVDGIGRYTTLGQTRDDAAGEAFDKVAKLLGLPYPGGV
EHHHHCCCEEEEEEECCCEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCC
EIDRLAAEGDPASISFPRPLLHDGSFNFSFSGLKTAVLNHVRKNPVQEDGQQLRDLCASF
CHHHHCCCCCCCCCCCCCCHHCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QRAACDVLVTKTLLAAETEGIGRVVVAGGVACNSALRRDMAREAADRGIELAIPSPSLCS
HHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
DNAAMLAVPGDFYLSRGISDGLSLDALVNWPLDTIRTRLES
CCCEEEEECCHHHHHCCCCCCCCCHHEECCCHHHHHHHHCC
>Mature Secondary Structure
MLILTIETSCDETAAAVVRDGRTVLSSIVATQVKDHAVYGGVVPEIASRKHLESIPVVID
CEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHH
EALRTASVSLDAIEGVAVTQGPGLAGALLVGTAVAKAIAFARRLPIVGVNHIEGHLSAIF
HHHHHHHCCHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHE
LEREVAFPFVALAVSGGHTHLYRVDGIGRYTTLGQTRDDAAGEAFDKVAKLLGLPYPGGV
EHHHHCCCEEEEEEECCCEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCC
EIDRLAAEGDPASISFPRPLLHDGSFNFSFSGLKTAVLNHVRKNPVQEDGQQLRDLCASF
CHHHHCCCCCCCCCCCCCCHHCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QRAACDVLVTKTLLAAETEGIGRVVVAGGVACNSALRRDMAREAADRGIELAIPSPSLCS
HHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
DNAAMLAVPGDFYLSRGISDGLSLDALVNWPLDTIRTRLES
CCCEEEEECCHHHHHCCCCCCCCCHHEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA