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The map label for this gene is csd [H]

Identifier: 78222514

GI number: 78222514

Start: 1462945

End: 1464090

Strand: Direct

Name: csd [H]

Synonym: Gmet_1300

Alternate gene names: 78222514

Gene position: 1462945-1464090 (Clockwise)

Preceding gene: 78222513

Following gene: 78222515

Centisome position: 36.6

GC content: 64.83

Gene sequence:

>1146_bases
ATGTCGCTTTATCTCGATAATGCAGCAACGTCGTATCCCAAGCCTGAACCGGTCTATGAAGCGGTGAACAGGGCCATGCG
TGACGTGGGGGTCAGCCCGGGCAGGGGAGGGTACCGTCGCGGCATTGAGGCGAGCCGTCTTCTCTTTGAAACGCGGGAGT
CGGTGGCGGCCCTCTTCGGCATCGGCGATTCGTCGCGGGTGGTCTTCACCCATAGTGCCACCGAGGCCCTCAATCTGGCG
GTGCTGGGGCTTGTGCGGCCCGGCGACCACGTGGTCACCACCTCGGCGGAACACAATTCGCTCGTCCGCCCGCTCCATCT
GGCCGGGCAGCGGGGAGTCGAGATTTCCTGGATCGAGGCCGACCGTCGCGGGTTTGTCTCCCCGGACCAGATCGCTGCCG
CCATCCGCCCTTCGACGCGACTCATTGCCCTTGCCCACTGCTCCAACGTGACCGGCGCCATCCAACCGGTCACGGAAATT
GCCGCCGTGGCCCGTCGCGCCGGAGTTCTCACCCTTGTGGATGCCGCCCAGAGCGCGGGAATGATTCCCCTCGACGTTTC
GGCCATGGGGATCGATCTCCTGGCAGCGCCGGGGCACAAGGGGCTCATGGGGCCCCCGGGGACCGGCATTCTCTGTGTGG
CCGAAGGTGTGGATCTGGAACCGCTTTTTGTCGGGGGGACAGGGGGATACTCGTCGGGCGTGGAACAGCCCGACGCCATG
CCCGAACGGTTCGAAAGCGGGACCCACAATCTGCCGGGCATCGCCGGTCTCGGGGCAGGTGTCGATTTCATCCGAACCGT
GGGACTGGAAGTGATCCGGAAGCGGGAAGAGGAACTGGTCGCCTTTCTCATGGATGGGCTCGGAGCGCTGCCGGGAGTAA
CCTGCCACGGACCATTGCCGGACGAACCGCGGGGGGGGCTCGTGAGTTTCACGGTGGAGGGAGTCGACCCTCAGACCATC
GGTTTCCGGCTCGATCAGGAGTTCGATATCTGCGTGCGGGTAGGGCTCCACTGCGCCCCTGCTGCCCACCGGACCATCGG
CACCTATCCCGGCGGCGCGGTCAGGGTGAGCCCCGGCTACTTCACCACAGATGAAGAGATCGGTACCTTTCTCCAGGCGA
TGGGGAAGATTATCAGCTCTCCGTGA

Upstream 100 bases:

>100_bases
AGGGGAAGGATTTTCGTGAACCCGGTGCTCAAGGCGCGGCCGTATTTCCCGACCTTGAATTCCGTTGCTAAATAGCTGAC
GTCATGCTAGCTTTTTCCTA

Downstream 100 bases:

>100_bases
GAGTCCCCTTTCCGTACGGTTATGTCCGTGTTATGGCCCCACAACTCATGATGAATGATTCGTCAAAGGGGGAAGTATGA
ATAAGCGATTCCTTGTTGCA

Product: cysteine desulphurase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSLYLDNAATSYPKPEPVYEAVNRAMRDVGVSPGRGGYRRGIEASRLLFETRESVAALFGIGDSSRVVFTHSATEALNLA
VLGLVRPGDHVVTTSAEHNSLVRPLHLAGQRGVEISWIEADRRGFVSPDQIAAAIRPSTRLIALAHCSNVTGAIQPVTEI
AAVARRAGVLTLVDAAQSAGMIPLDVSAMGIDLLAAPGHKGLMGPPGTGILCVAEGVDLEPLFVGGTGGYSSGVEQPDAM
PERFESGTHNLPGIAGLGAGVDFIRTVGLEVIRKREEELVAFLMDGLGALPGVTCHGPLPDEPRGGLVSFTVEGVDPQTI
GFRLDQEFDICVRVGLHCAPAAHRTIGTYPGGAVRVSPGYFTTDEEIGTFLQAMGKIISSP

Sequences:

>Translated_381_residues
MSLYLDNAATSYPKPEPVYEAVNRAMRDVGVSPGRGGYRRGIEASRLLFETRESVAALFGIGDSSRVVFTHSATEALNLA
VLGLVRPGDHVVTTSAEHNSLVRPLHLAGQRGVEISWIEADRRGFVSPDQIAAAIRPSTRLIALAHCSNVTGAIQPVTEI
AAVARRAGVLTLVDAAQSAGMIPLDVSAMGIDLLAAPGHKGLMGPPGTGILCVAEGVDLEPLFVGGTGGYSSGVEQPDAM
PERFESGTHNLPGIAGLGAGVDFIRTVGLEVIRKREEELVAFLMDGLGALPGVTCHGPLPDEPRGGLVSFTVEGVDPQTI
GFRLDQEFDICVRVGLHCAPAAHRTIGTYPGGAVRVSPGYFTTDEEIGTFLQAMGKIISSP
>Mature_380_residues
SLYLDNAATSYPKPEPVYEAVNRAMRDVGVSPGRGGYRRGIEASRLLFETRESVAALFGIGDSSRVVFTHSATEALNLAV
LGLVRPGDHVVTTSAEHNSLVRPLHLAGQRGVEISWIEADRRGFVSPDQIAAAIRPSTRLIALAHCSNVTGAIQPVTEIA
AVARRAGVLTLVDAAQSAGMIPLDVSAMGIDLLAAPGHKGLMGPPGTGILCVAEGVDLEPLFVGGTGGYSSGVEQPDAMP
ERFESGTHNLPGIAGLGAGVDFIRTVGLEVIRKREEELVAFLMDGLGALPGVTCHGPLPDEPRGGLVSFTVEGVDPQTIG
FRLDQEFDICVRVGLHCAPAAHRTIGTYPGGAVRVSPGYFTTDEEIGTFLQAMGKIISSP

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=381, Percent_Identity=28.8713910761155, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI156713448, Length=323, Percent_Identity=28.7925696594427, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1787970, Length=386, Percent_Identity=30.8290155440415, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789175, Length=391, Percent_Identity=29.156010230179, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI48994898, Length=395, Percent_Identity=29.1139240506329, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25143064, Length=382, Percent_Identity=28.0104712041885, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17533177, Length=213, Percent_Identity=30.9859154929577, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193211090, Length=329, Percent_Identity=24.6200607902736, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=388, Percent_Identity=27.319587628866, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI20129463, Length=382, Percent_Identity=30.6282722513089, Blast_Score=125, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 39890; Mature: 39759

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYLDNAATSYPKPEPVYEAVNRAMRDVGVSPGRGGYRRGIEASRLLFETRESVAALFG
CEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHC
IGDSSRVVFTHSATEALNLAVLGLVRPGDHVVTTSAEHNSLVRPLHLAGQRGVEISWIEA
CCCCCEEEEEECCHHHHEEEEEEEECCCCEEEEECCCCCCCCCHHHHCCCCCCEEEEEEC
DRRGFVSPDQIAAAIRPSTRLIALAHCSNVTGAIQPVTEIAAVARRAGVLTLVDAAQSAG
CCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEHHHHCC
MIPLDVSAMGIDLLAAPGHKGLMGPPGTGILCVAEGVDLEPLFVGGTGGYSSGVEQPDAM
CCEEEHHHHCEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCC
PERFESGTHNLPGIAGLGAGVDFIRTVGLEVIRKREEELVAFLMDGLGALPGVTCHGPLP
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCC
DEPRGGLVSFTVEGVDPQTIGFRLDQEFDICVRVGLHCAPAAHRTIGTYPGGAVRVSPGY
CCCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHCCCCCCCHHCCCCCCCCCEEEECCCE
FTTDEEIGTFLQAMGKIISSP
ECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLYLDNAATSYPKPEPVYEAVNRAMRDVGVSPGRGGYRRGIEASRLLFETRESVAALFG
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHC
IGDSSRVVFTHSATEALNLAVLGLVRPGDHVVTTSAEHNSLVRPLHLAGQRGVEISWIEA
CCCCCEEEEEECCHHHHEEEEEEEECCCCEEEEECCCCCCCCCHHHHCCCCCCEEEEEEC
DRRGFVSPDQIAAAIRPSTRLIALAHCSNVTGAIQPVTEIAAVARRAGVLTLVDAAQSAG
CCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEHHHHCC
MIPLDVSAMGIDLLAAPGHKGLMGPPGTGILCVAEGVDLEPLFVGGTGGYSSGVEQPDAM
CCEEEHHHHCEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCC
PERFESGTHNLPGIAGLGAGVDFIRTVGLEVIRKREEELVAFLMDGLGALPGVTCHGPLP
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCC
DEPRGGLVSFTVEGVDPQTIGFRLDQEFDICVRVGLHCAPAAHRTIGTYPGGAVRVSPGY
CCCCCCEEEEEEECCCCCEEEEEECCCCCCHHHHCCCCCCCHHCCCCCCCCCEEEECCCE
FTTDEEIGTFLQAMGKIISSP
ECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]