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The map label for this gene is cph2 [H]

Identifier: 78222512

GI number: 78222512

Start: 1460524

End: 1461585

Strand: Direct

Name: cph2 [H]

Synonym: Gmet_1298

Alternate gene names: 78222512

Gene position: 1460524-1461585 (Clockwise)

Preceding gene: 78222510

Following gene: 78222513

Centisome position: 36.54

GC content: 56.97

Gene sequence:

>1062_bases
ATGGAACATAGCTTGAAATGCACCATTGAGCTGCTCGAAGAGGAAGTCAGCGCCCTCAGGGAGTTGATTGAGGTGGCGAG
GATGGTGGTTTCCACCCTCGAACTTGATCAGGTCCTCCTGGAGATACTGACCAGCGCGATGCGCTTTGCCGACGCCTCCG
CCGGAAGCATTGTCCTCTACGACACCGTTCAGGGGGGACTGACTCTCCACGCCCACCAGGGGTTTACCCCCGAATTCGTC
TTGGCCGAGCGGTGGGAAATCCGCCCTGGAGGGGTCACTGAACGGGTTATCTCCGGTGGCGAGATCCTGTTCGTCAACGA
CACCGAAGATAACCCCCTCCTTGTCGACCCCATTGTCATCAGGGAGGGGATCAGATCTCAGGCCTGCATTCCCCTTAAAG
TGCAGAGCCGGCTTGCGGGCATTCTCTACCTGTGCGATTTTGTCCCCCGGGAGTTCGATCGGGAGAGAATGAAACTTCTG
GACGTCCTCGCCTCCTTTGCCGCCATGGCCATCGATAATGCTCAGCTCCATGAGCGGACCCGGCTCATGGCCATAACCGA
CGCCCTGACCGGTCTTTACAACCGGCGCTACTTTCAGCAGATGTTCAGTCGGGAACTGAACCGGGCCAAGCGTTACGGCA
ACCCCCTCTCACTGATCATGATGGACGTGGATGACTTCAAGAAGTTCAATGATACCTATGGACATCCCCTTGGCGACAAG
CTCCTAGGGAGCATGGGAGATATTCTCACGGAGGCGCTGCGCAATACCGATTTTGCCTTTCGCTACGGGGGCGAGGAGTT
TATCGTGCTCTTGCCGGAAACCGACTTTTCCAGCGCGCTTAATGTTGCGGAGCGGCTCCGGGAGTCCGTGGAACAGAAGA
GTGTCGACGAAATGCGAGGGATCGCTCTCAATGCCGTAACCGTAAGTGTCGGCGTAGTCTCCTATCCCCAGGACGGCGAG
ACCAGCGACGACCTCCTCAATGGGGTGGATGAACTCCTCTATCGGGCCAAGGAGTATGGCAAGAACAGGGTCTACTACCG
GACTATGGGAGAAAAACCATGA

Upstream 100 bases:

>100_bases
CATCGGCCGATTTGCTGTGTGTGCAGGTGGGGTGCTGGCAATTTACATCCCTGAGGTTTTGTGTTAGTTTTTTTCATTTT
TCTGGCGGACGGAACAGACC

Downstream 100 bases:

>100_bases
GGCGCTCTACAATGGCGACCATGAGGATGCCGTTGGCTCTCTCCGTTTTGCTCGGGATGGCGGCAGTCCTCGGTGGGTGC
GGGACGGTTTCGGAACTTTT

Product: diguanylate cyclase with GAF sensor

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEHSLKCTIELLEEEVSALRELIEVARMVVSTLELDQVLLEILTSAMRFADASAGSIVLYDTVQGGLTLHAHQGFTPEFV
LAERWEIRPGGVTERVISGGEILFVNDTEDNPLLVDPIVIREGIRSQACIPLKVQSRLAGILYLCDFVPREFDRERMKLL
DVLASFAAMAIDNAQLHERTRLMAITDALTGLYNRRYFQQMFSRELNRAKRYGNPLSLIMMDVDDFKKFNDTYGHPLGDK
LLGSMGDILTEALRNTDFAFRYGGEEFIVLLPETDFSSALNVAERLRESVEQKSVDEMRGIALNAVTVSVGVVSYPQDGE
TSDDLLNGVDELLYRAKEYGKNRVYYRTMGEKP

Sequences:

>Translated_353_residues
MEHSLKCTIELLEEEVSALRELIEVARMVVSTLELDQVLLEILTSAMRFADASAGSIVLYDTVQGGLTLHAHQGFTPEFV
LAERWEIRPGGVTERVISGGEILFVNDTEDNPLLVDPIVIREGIRSQACIPLKVQSRLAGILYLCDFVPREFDRERMKLL
DVLASFAAMAIDNAQLHERTRLMAITDALTGLYNRRYFQQMFSRELNRAKRYGNPLSLIMMDVDDFKKFNDTYGHPLGDK
LLGSMGDILTEALRNTDFAFRYGGEEFIVLLPETDFSSALNVAERLRESVEQKSVDEMRGIALNAVTVSVGVVSYPQDGE
TSDDLLNGVDELLYRAKEYGKNRVYYRTMGEKP
>Mature_353_residues
MEHSLKCTIELLEEEVSALRELIEVARMVVSTLELDQVLLEILTSAMRFADASAGSIVLYDTVQGGLTLHAHQGFTPEFV
LAERWEIRPGGVTERVISGGEILFVNDTEDNPLLVDPIVIREGIRSQACIPLKVQSRLAGILYLCDFVPREFDRERMKLL
DVLASFAAMAIDNAQLHERTRLMAITDALTGLYNRRYFQQMFSRELNRAKRYGNPLSLIMMDVDDFKKFNDTYGHPLGDK
LLGSMGDILTEALRNTDFAFRYGGEEFIVLLPETDFSSALNVAERLRESVEQKSVDEMRGIALNAVTVSVGVVSYPQDGE
TSDDLLNGVDELLYRAKEYGKNRVYYRTMGEKP

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=39.873417721519, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=39.3063583815029, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787262, Length=193, Percent_Identity=33.6787564766839, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=31.7647058823529, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082007, Length=173, Percent_Identity=35.2601156069364, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=31.3953488372093, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=33.7423312883436, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787802, Length=215, Percent_Identity=30.2325581395349, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788085, Length=162, Percent_Identity=32.7160493827161, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87081974, Length=160, Percent_Identity=30, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788381, Length=162, Percent_Identity=30.8641975308642, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081977, Length=209, Percent_Identity=24.4019138755981, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 39792; Mature: 39792

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHSLKCTIELLEEEVSALRELIEVARMVVSTLELDQVLLEILTSAMRFADASAGSIVLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
DTVQGGLTLHAHQGFTPEFVLAERWEIRPGGVTERVISGGEILFVNDTEDNPLLVDPIVI
EECCCCEEEEECCCCCCCCHHHHCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEECHHHH
REGIRSQACIPLKVQSRLAGILYLCDFVPREFDRERMKLLDVLASFAAMAIDNAQLHERT
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RLMAITDALTGLYNRRYFQQMFSRELNRAKRYGNPLSLIMMDVDDFKKFNDTYGHPLGDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCHHH
LLGSMGDILTEALRNTDFAFRYGGEEFIVLLPETDFSSALNVAERLRESVEQKSVDEMRG
HHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHC
IALNAVTVSVGVVSYPQDGETSDDLLNGVDELLYRAKEYGKNRVYYRTMGEKP
CEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
>Mature Secondary Structure
MEHSLKCTIELLEEEVSALRELIEVARMVVSTLELDQVLLEILTSAMRFADASAGSIVLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
DTVQGGLTLHAHQGFTPEFVLAERWEIRPGGVTERVISGGEILFVNDTEDNPLLVDPIVI
EECCCCEEEEECCCCCCCCHHHHCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEECHHHH
REGIRSQACIPLKVQSRLAGILYLCDFVPREFDRERMKLLDVLASFAAMAIDNAQLHERT
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RLMAITDALTGLYNRRYFQQMFSRELNRAKRYGNPLSLIMMDVDDFKKFNDTYGHPLGDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCHHH
LLGSMGDILTEALRNTDFAFRYGGEEFIVLLPETDFSSALNVAERLRESVEQKSVDEMRG
HHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHC
IALNAVTVSVGVVSYPQDGETSDDLLNGVDELLYRAKEYGKNRVYYRTMGEKP
CEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]