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The map label for this gene is lytE [H]

Identifier: 78222385

GI number: 78222385

Start: 1292647

End: 1293672

Strand: Direct

Name: lytE [H]

Synonym: Gmet_1169

Alternate gene names: 78222385

Gene position: 1292647-1293672 (Clockwise)

Preceding gene: 78222384

Following gene: 78222386

Centisome position: 32.34

GC content: 53.61

Gene sequence:

>1026_bases
ATGAGCCTGCGATTGCGACTTACAGCGCTTTCCGTAATCCTCTTAGCCTTTCCCGCCCTGTCCCACGCCGCAAAAACCCA
CAAGATCAGAAAAAGCGAAACCGTTTACTCTATCGCGAAGAAGTACCACGTTAGTGCGAAAGATCTAAAATCGGCCAACA
ACCTCACTAATGCCCGGATAAAGCCGGGAACAGTGCTTGTCATCCCGTCTCGCGCCGCAGCAGAGTCAAGCGCGGACTCT
TCCACCCCTGCCAGCTATAAGGTGAAAAAAGGTGATACCCTGGCAAAGGTTGCGCGGAAGACCGGCGTTTCCGTGGCTGA
GTTGCGACGTTTGAACGGCATAGGGAAGGGCAGACTCAAGCCCGGTCGTCTCCTTGCACTCCAGGCAGTGGAATCCAATG
AAACGGTTACCGCGAAGCTTTCCCTGAAAAAGCCCCTGAAACACCTTGATATCTACGATGAAAAAGAATACGAGCAGAGT
CTGAGCGAGTTGGTGGAGTTGGACCCGAACCGTCCAGCTGACTTCACGAAGAGCGTGAAACTCGATGTCGATGGTGTCTC
TGAACTCAAAAAAACTGCCTACAGCTTCATCGGCACCAAGTATCGTTTCGGCGGCACCACCCGTCGGGGGCTCGACTGTT
CCAGTTTTGTCCAGCACGTCTTCCGCGAGCTCGACGTAACTCTTCCCCGCACGGCCCGGGAACAGTTCCATGTGGGAAAT
TCGGTTGCTCCCGGCGACCTGCAGAAGGGTGACCTCCTCTTCTTCCAGACCTATGCGCGTTTCCCGTCCCATGTTGGCAT
CTATCTCGGCAACAACAAGATGATTCACGCCTCGTCGCGAGACCGTCGGGTCGTTATTTCCTCTGTTGATACTCCCTACT
ACCGTTCCCGTTTCCTTGGTGCGAAGCGGATTGCCGAGGTTAATCCCGATATCCTGAAACTCGATGACCTGATTTCCGGT
GTTGAGGAAGAAGGGCTCGAGGAAATTTTGACGAATGACACCCTTGGGGTCAGTCTTTTGAAATAG

Upstream 100 bases:

>100_bases
ATGTTGGCCGGGGGGGGAATAAAGGTTGACAGATGAGAGATGGTTTGTTATAAAAAGCTCGTTTTCGTTTCAATTTAATA
AAACAAATGAAGGAGGGGAT

Downstream 100 bases:

>100_bases
GGTTTTCGCCCTGCGTCGTTTGCGCACGAAAAAATCCGGCTCTTGCGGCCGGATTTTTTTTTGAGGTGTCCATGCTTCCT
CTTATCGTGACAGCCGCCGT

Product: NLP/P60:peptidoglycan-binding LysM

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP33; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytE; Phosphatase-associated protein papQ [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSLRLRLTALSVILLAFPALSHAAKTHKIRKSETVYSIAKKYHVSAKDLKSANNLTNARIKPGTVLVIPSRAAAESSADS
STPASYKVKKGDTLAKVARKTGVSVAELRRLNGIGKGRLKPGRLLALQAVESNETVTAKLSLKKPLKHLDIYDEKEYEQS
LSELVELDPNRPADFTKSVKLDVDGVSELKKTAYSFIGTKYRFGGTTRRGLDCSSFVQHVFRELDVTLPRTAREQFHVGN
SVAPGDLQKGDLLFFQTYARFPSHVGIYLGNNKMIHASSRDRRVVISSVDTPYYRSRFLGAKRIAEVNPDILKLDDLISG
VEEEGLEEILTNDTLGVSLLK

Sequences:

>Translated_341_residues
MSLRLRLTALSVILLAFPALSHAAKTHKIRKSETVYSIAKKYHVSAKDLKSANNLTNARIKPGTVLVIPSRAAAESSADS
STPASYKVKKGDTLAKVARKTGVSVAELRRLNGIGKGRLKPGRLLALQAVESNETVTAKLSLKKPLKHLDIYDEKEYEQS
LSELVELDPNRPADFTKSVKLDVDGVSELKKTAYSFIGTKYRFGGTTRRGLDCSSFVQHVFRELDVTLPRTAREQFHVGN
SVAPGDLQKGDLLFFQTYARFPSHVGIYLGNNKMIHASSRDRRVVISSVDTPYYRSRFLGAKRIAEVNPDILKLDDLISG
VEEEGLEEILTNDTLGVSLLK
>Mature_340_residues
SLRLRLTALSVILLAFPALSHAAKTHKIRKSETVYSIAKKYHVSAKDLKSANNLTNARIKPGTVLVIPSRAAAESSADSS
TPASYKVKKGDTLAKVARKTGVSVAELRRLNGIGKGRLKPGRLLALQAVESNETVTAKLSLKKPLKHLDIYDEKEYEQSL
SELVELDPNRPADFTKSVKLDVDGVSELKKTAYSFIGTKYRFGGTTRRGLDCSSFVQHVFRELDVTLPRTAREQFHVGNS
VAPGDLQKGDLLFFQTYARFPSHVGIYLGNNKMIHASSRDRRVVISSVDTPYYRSRFLGAKRIAEVNPDILKLDDLISGV
EEEGLEEILTNDTLGVSLLK

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1788501, Length=124, Percent_Identity=41.9354838709677, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788001, Length=121, Percent_Identity=42.1487603305785, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787944, Length=123, Percent_Identity=36.5853658536585, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786421, Length=113, Percent_Identity=38.9380530973451, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786405, Length=104, Percent_Identity=34.6153846153846, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 37640; Mature: 37508

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLRLTALSVILLAFPALSHAAKTHKIRKSETVYSIAKKYHVSAKDLKSANNLTNARI
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEE
KPGTVLVIPSRAAAESSADSSTPASYKVKKGDTLAKVARKTGVSVAELRRLNGIGKGRLK
CCCEEEEECCHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCC
PGRLLALQAVESNETVTAKLSLKKPLKHLDIYDEKEYEQSLSELVELDPNRPADFTKSVK
CCEEEEEEEECCCCEEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
LDVDGVSELKKTAYSFIGTKYRFGGTTRRGLDCSSFVQHVFRELDVTLPRTAREQFHVGN
EECCCHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCC
SVAPGDLQKGDLLFFQTYARFPSHVGIYLGNNKMIHASSRDRRVVISSVDTPYYRSRFLG
CCCCCCCCCCCEEEEEHHHCCCCCEEEEECCCEEEEECCCCCEEEEECCCCHHHHHHHHH
AKRIAEVNPDILKLDDLISGVEEEGLEEILTNDTLGVSLLK
HHHHHHCCCCCEEHHHHHCCHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure 
SLRLRLTALSVILLAFPALSHAAKTHKIRKSETVYSIAKKYHVSAKDLKSANNLTNARI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEE
KPGTVLVIPSRAAAESSADSSTPASYKVKKGDTLAKVARKTGVSVAELRRLNGIGKGRLK
CCCEEEEECCHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCC
PGRLLALQAVESNETVTAKLSLKKPLKHLDIYDEKEYEQSLSELVELDPNRPADFTKSVK
CCEEEEEEEECCCCEEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
LDVDGVSELKKTAYSFIGTKYRFGGTTRRGLDCSSFVQHVFRELDVTLPRTAREQFHVGN
EECCCHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCC
SVAPGDLQKGDLLFFQTYARFPSHVGIYLGNNKMIHASSRDRRVVISSVDTPYYRSRFLG
CCCCCCCCCCCEEEEEHHHCCCCCEEEEECCCEEEEECCCCCEEEEECCCCHHHHHHHHH
AKRIAEVNPDILKLDDLISGVEEEGLEEILTNDTLGVSLLK
HHHHHHCCCCCEEHHHHHCCHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457885; 9579061; 9384377; 8045898 [H]