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The map label for this gene is pdxJ

Identifier: 78188462

GI number: 78188462

Start: 563334

End: 564041

Strand: Reverse

Name: pdxJ

Synonym: Cag_0484

Alternate gene names: 78188462

Gene position: 564041-563334 (Counterclockwise)

Preceding gene: 78188465

Following gene: 78188461

Centisome position: 21.93

GC content: 49.58

Gene sequence:

>708_bases
ATGAGATTAGCTGTTAATATTGACCATGTTGCTACGTTGCGCAATGCACGTGGCGAATTTCATCCTGACCCTGTTGAAGC
GGCGCTTATTGCTGAGCAAGCGGGTGCCGCAGGCATTGTATGCCACCTCCGTGAAGATCGGCGACATATTAAGGATGACG
ACCTCCGTCGCCTTCGTGCGGCTGTTACTACCAAGCTTGACCTTGAAATGGCAATGACCGAAGAGCTGCAAGCTATTGCC
CTTGCCACAAAGCCTGAACTTATTACGTTAGTACCTGAAAAACGTGAGGAGCTTACCACTGAAGGTGGATTTGATATTGT
GCGCCATTTCGATACGCTCAAAGCCTACTTGCAACCTTTTCGCTCTGCTGGCATTGAGGTGAGTTTGTTTATTGAGCCTG
ACAAGCAGGCTATTGAGCTTGCCGCTCAAGCGGGTGCCGATATTGTGGAGTTGCACACGGGGCTTTATGCGTTAAAAGCG
GGTGAAGCGCAAGAAGAGGAACTGACGCGTATTGGCAATGCCGCAGCTTTTGCTCGGAACATTGGCTTAAAAGTGGTTGC
TGGACATGGCTTAAATTACAGCAACATTGCCCCGTTCCGCAATATTGTGGAAATTGAAGAGGTGAGCATTGGGCACGCCA
TTATAACCCGTGCCATTTTTAGCGGTTTAGAGGGTGCCGTCCGCGAAATGGTTGCACTCATTCGCTAA

Upstream 100 bases:

>100_bases
TCCGCACGTTTCCCAAAAGAATTTTATTACCTTCGCTATCTTTTTTTTGCGGGCTATACACACATAGCAAAACACTCAGA
ACATTGACTTTACACCATCC

Downstream 100 bases:

>100_bases
GTAGCATAACTGCACCACAATAAATCCTTGCAGAGATATAATAATCCGCTTGACAATTCTTTTTTTGATAGACTATGACC
GATACCATCACCATTATTTT

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRLAVNIDHVATLRNARGEFHPDPVEAALIAEQAGAAGIVCHLREDRRHIKDDDLRRLRAAVTTKLDLEMAMTEELQAIA
LATKPELITLVPEKREELTTEGGFDIVRHFDTLKAYLQPFRSAGIEVSLFIEPDKQAIELAAQAGADIVELHTGLYALKA
GEAQEEELTRIGNAAAFARNIGLKVVAGHGLNYSNIAPFRNIVEIEEVSIGHAIITRAIFSGLEGAVREMVALIR

Sequences:

>Translated_235_residues
MRLAVNIDHVATLRNARGEFHPDPVEAALIAEQAGAAGIVCHLREDRRHIKDDDLRRLRAAVTTKLDLEMAMTEELQAIA
LATKPELITLVPEKREELTTEGGFDIVRHFDTLKAYLQPFRSAGIEVSLFIEPDKQAIELAAQAGADIVELHTGLYALKA
GEAQEEELTRIGNAAAFARNIGLKVVAGHGLNYSNIAPFRNIVEIEEVSIGHAIITRAIFSGLEGAVREMVALIR
>Mature_235_residues
MRLAVNIDHVATLRNARGEFHPDPVEAALIAEQAGAAGIVCHLREDRRHIKDDDLRRLRAAVTTKLDLEMAMTEELQAIA
LATKPELITLVPEKREELTTEGGFDIVRHFDTLKAYLQPFRSAGIEVSLFIEPDKQAIELAAQAGADIVELHTGLYALKA
GEAQEEELTRIGNAAAFARNIGLKVVAGHGLNYSNIAPFRNIVEIEEVSIGHAIITRAIFSGLEGAVREMVALIR

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=233, Percent_Identity=55.793991416309, Blast_Score=254, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_CHLCH (Q3ATB8)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_378800.1
- ProteinModelPortal:   Q3ATB8
- SMR:   Q3ATB8
- STRING:   Q3ATB8
- GeneID:   3746353
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0484
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- BioCyc:   CCHL340177:CAG_0484-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 25730; Mature: 25730

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: ACT_SITE 42-42 ACT_SITE 69-69 ACT_SITE 189-189 BINDING 6-6 BINDING 17-17 BINDING 44-44 BINDING 49-49 BINDING 99-99 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAVNIDHVATLRNARGEFHPDPVEAALIAEQAGAAGIVCHLREDRRHIKDDDLRRLRA
CEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEEHHHCCCCHHHHHHHHH
AVTTKLDLEMAMTEELQAIALATKPELITLVPEKREELTTEGGFDIVRHFDTLKAYLQPF
HHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
RSAGIEVSLFIEPDKQAIELAAQAGADIVELHTGLYALKAGEAQEEELTRIGNAAAFARN
HHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHCHHEEECCCCHHHHHHHHCCHHHHHHH
IGLKVVAGHGLNYSNIAPFRNIVEIEEVSIGHAIITRAIFSGLEGAVREMVALIR
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRLAVNIDHVATLRNARGEFHPDPVEAALIAEQAGAAGIVCHLREDRRHIKDDDLRRLRA
CEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEEHHHCCCCHHHHHHHHH
AVTTKLDLEMAMTEELQAIALATKPELITLVPEKREELTTEGGFDIVRHFDTLKAYLQPF
HHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
RSAGIEVSLFIEPDKQAIELAAQAGADIVELHTGLYALKAGEAQEEELTRIGNAAAFARN
HHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHCHHEEECCCCHHHHHHHHCCHHHHHHH
IGLKVVAGHGLNYSNIAPFRNIVEIEEVSIGHAIITRAIFSGLEGAVREMVALIR
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA