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The map label for this gene is trpG [H]

Identifier: 78188279

GI number: 78188279

Start: 326981

End: 327544

Strand: Reverse

Name: trpG [H]

Synonym: Cag_0298

Alternate gene names: 78188279

Gene position: 327544-326981 (Counterclockwise)

Preceding gene: 78188280

Following gene: 78188278

Centisome position: 12.73

GC content: 46.81

Gene sequence:

>564_bases
ATGATTTTTGTTATTGATAATTACGACTCCTTTACCTACAACTTAGTGCAATACATTGGGGAGTCGGGGGCTGAGGTTGA
AGTGCGCCGCAACAATGAATGTTCGGTTGCTGAAGTGTTAGCATTAGCGCCTGAAAAAATTGTGATTTCTCCCGGTCCAG
GTACGCCCAATGATGCAGGTATTTCCATTGAACTCATTCATGCCGTAAAAGGAACTATTCCCTTGCTGGGCGTCTGCCTT
GGGCATCAATCCATTGGAGCGGCACTTGGTGGCAACGTCATTCGTGCGCCACACATTATGCACGGCAAAACGTCGCAAGT
CTATCACGATGGCAACGGCATTTTTAAAAATGTTGCCAATCCCTTTACCGCTACGCGTTACCATTCGTTAATTGTAGAGC
GCGAAAGTTTGCCCGAAGCACTCACCGTGCGTGCTTGGACGGAAGATGGCATTATTATGGGCATGGACTCGGTAGCGCTT
AAACTGTATGGCGTCCAATTCCATCCCGAATCCATTATGACGGCAGAGGGAAAAAAGCTTATTGGCAACTTTCTTGAATT
GTAA

Upstream 100 bases:

>100_bases
GCACGCCGCAAAGTTACCATGAGCGCCTCTTACGAAACCATGTTTCGCTCTGTTGCTGGCTTAAGTGGTAATTCCTTATT
TATATAATTTTTAGAGAACA

Downstream 100 bases:

>100_bases
GGCATCTCTTGAATGGAAAATTCCAGCAACATAGCACGGCAACGCAAAGCCGTTAAAAGCCGCGCTTGTGAACCAAACGA
AAATCTCTTAGCGGCTGACG

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MIFVIDNYDSFTYNLVQYIGESGAEVEVRRNNECSVAEVLALAPEKIVISPGPGTPNDAGISIELIHAVKGTIPLLGVCL
GHQSIGAALGGNVIRAPHIMHGKTSQVYHDGNGIFKNVANPFTATRYHSLIVERESLPEALTVRAWTEDGIIMGMDSVAL
KLYGVQFHPESIMTAEGKKLIGNFLEL

Sequences:

>Translated_187_residues
MIFVIDNYDSFTYNLVQYIGESGAEVEVRRNNECSVAEVLALAPEKIVISPGPGTPNDAGISIELIHAVKGTIPLLGVCL
GHQSIGAALGGNVIRAPHIMHGKTSQVYHDGNGIFKNVANPFTATRYHSLIVERESLPEALTVRAWTEDGIIMGMDSVAL
KLYGVQFHPESIMTAEGKKLIGNFLEL
>Mature_187_residues
MIFVIDNYDSFTYNLVQYIGESGAEVEVRRNNECSVAEVLALAPEKIVISPGPGTPNDAGISIELIHAVKGTIPLLGVCL
GHQSIGAALGGNVIRAPHIMHGKTSQVYHDGNGIFKNVANPFTATRYHSLIVERESLPEALTVRAWTEDGIIMGMDSVAL
KLYGVQFHPESIMTAEGKKLIGNFLEL

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=55.6756756756757, Blast_Score=226, Evalue=6e-61,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=39.0374331550802, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786215, Length=158, Percent_Identity=29.1139240506329, Blast_Score=60, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=49.1978609625668, Blast_Score=182, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=31.6037735849057, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281365319, Length=116, Percent_Identity=31.8965517241379, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20200; Mature: 20200

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFVIDNYDSFTYNLVQYIGESGAEVEVRRNNECSVAEVLALAPEKIVISPGPGTPNDAG
CEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCCC
ISIELIHAVKGTIPLLGVCLGHQSIGAALGGNVIRAPHIMHGKTSQVYHDGNGIFKNVAN
EEEEEEEHHHCCHHHHHHHHCCHHHHHHHCCCEEECCEEECCCCCEEEECCCCHHHHCCC
PFTATRYHSLIVERESLPEALTVRAWTEDGIIMGMDSVALKLYGVQFHPESIMTAEGKKL
CCHHHHHHHHEEECCCCCCEEEEEEECCCCEEEECCCEEEEEEEEEECCCHHCCCCCHHH
IGNFLEL
HHHHHCC
>Mature Secondary Structure
MIFVIDNYDSFTYNLVQYIGESGAEVEVRRNNECSVAEVLALAPEKIVISPGPGTPNDAG
CEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCCC
ISIELIHAVKGTIPLLGVCLGHQSIGAALGGNVIRAPHIMHGKTSQVYHDGNGIFKNVAN
EEEEEEEHHHCCHHHHHHHHCCHHHHHHHCCCEEECCEEECCCCCEEEECCCCHHHHCCC
PFTATRYHSLIVERESLPEALTVRAWTEDGIIMGMDSVALKLYGVQFHPESIMTAEGKKL
CCHHHHHHHHEEECCCCCCEEEEEEECCCCEEEECCCEEEEEEEEEECCCHHCCCCCHHH
IGNFLEL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]