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The map label for this gene is folB [H]

Identifier: 78188214

GI number: 78188214

Start: 265541

End: 265921

Strand: Reverse

Name: folB [H]

Synonym: Cag_0233

Alternate gene names: 78188214

Gene position: 265921-265541 (Counterclockwise)

Preceding gene: 78188217

Following gene: 78188213

Centisome position: 10.34

GC content: 41.99

Gene sequence:

>381_bases
ATGCCTAACACACAAACACACTCACTCATTAAGCTTAATAAAATGACCTTTTACGCCTATCACGGCGTACTTCCGCAAGA
GGCTGTGTTGGGAGCACATTATGAAGTGGATGCTGAATTAAGCGTGGATATTACAAGCGCTGCGCTTAACGATGACCTTG
CGCAAACAATTGATTACGGGATGGTTTATATGCTTATAAAAACAGAGATGACCGAAACTCGGCAGCAATTGCTTGAAACC
CTCGCATATCGTATGGCACATAAATTGTTGGAAACTTTTGCTTTAGTAGATAGAACAACCATTGCTGTGCGCAAATTACA
TCCACCGCTTGGCGGAGAGTGTCATTCGGCTGAAGTATCTTATACGTTTATAAGGAGTTAA

Upstream 100 bases:

>100_bases
ACTATATTCCATACCTCTGTGATACAGAAAACGCACGGTATGTGTTTGATAGACAAAGTCCTACCCACTCATCGAAGCAA
AAAATATCATCCTCTCCACC

Downstream 100 bases:

>100_bases
TAGAATTAATTGATAAATGCAACGGAACAATGGACACGATAAGCTTGATAGATAACAGCTATAAACAATGGCTTGAAGGC
ATCAAGCAAAAAATAAAAAC

Product: dihydroneopterin aldolase family protein

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MPNTQTHSLIKLNKMTFYAYHGVLPQEAVLGAHYEVDAELSVDITSAALNDDLAQTIDYGMVYMLIKTEMTETRQQLLET
LAYRMAHKLLETFALVDRTTIAVRKLHPPLGGECHSAEVSYTFIRS

Sequences:

>Translated_126_residues
MPNTQTHSLIKLNKMTFYAYHGVLPQEAVLGAHYEVDAELSVDITSAALNDDLAQTIDYGMVYMLIKTEMTETRQQLLET
LAYRMAHKLLETFALVDRTTIAVRKLHPPLGGECHSAEVSYTFIRS
>Mature_125_residues
PNTQTHSLIKLNKMTFYAYHGVLPQEAVLGAHYEVDAELSVDITSAALNDDLAQTIDYGMVYMLIKTEMTETRQQLLETL
AYRMAHKLLETFALVDRTTIAVRKLHPPLGGECHSAEVSYTFIRS

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14219; Mature: 14087

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTQTHSLIKLNKMTFYAYHGVLPQEAVLGAHYEVDAELSVDITSAALNDDLAQTIDYG
CCCCCCCCEEEECCEEEEEECCCCCHHHHHCCCEEECCEEEEEEHHHHHHHHHHHHHHHH
MVYMLIKTEMTETRQQLLETLAYRMAHKLLETFALVDRTTIAVRKLHPPLGGECHSAEVS
HHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEE
YTFIRS
EEEECC
>Mature Secondary Structure 
PNTQTHSLIKLNKMTFYAYHGVLPQEAVLGAHYEVDAELSVDITSAALNDDLAQTIDYG
CCCCCCCEEEECCEEEEEECCCCCHHHHHCCCEEECCEEEEEEHHHHHHHHHHHHHHHH
MVYMLIKTEMTETRQQLLETLAYRMAHKLLETFALVDRTTIAVRKLHPPLGGECHSAEVS
HHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEE
YTFIRS
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]