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The map label for this gene is pheA [H]

Identifier: 78188163

GI number: 78188163

Start: 202983

End: 203834

Strand: Reverse

Name: pheA [H]

Synonym: Cag_0180

Alternate gene names: 78188163

Gene position: 203834-202983 (Counterclockwise)

Preceding gene: 78188164

Following gene: 78188162

Centisome position: 7.92

GC content: 45.54

Gene sequence:

>852_bases
ATGACAAACTTGCTGACTGCCTATCAAGGAGAGCCGGGAGCTTACAGCGAAATTGCTGCCCTCCGCCTTGGAACCCCCGT
ACCGTGCGCCTCGTTTGAGGAGGTGTTTGCCGCGGTTGAAAGTGAACGGGTTGATTATGCTGTTATTCCTATTGAAAATT
CGCTTGGCGGTAGTATTCACCAAAATTATGATTTACTGCTTCAGCATCCTGTCATTATTGAGGCTGAAACCTTTGTGAAG
GTGGAACATTGTTTGCTTGGTTTGCCGAATGCTTCGTTAGAGACAGCGGGGCGTGTGCTTTCGCATCCGCAAGCATTGGC
GCAATGCCGCAACTTTTTTGCGACTCATCCTCACCTTAAAGCTGAAGTTGCTTACGATACGGCTGGTAGCGCAAAAATGA
TTGCTGAAGAAAAGGATCCTACGAAGTTTGCACTTGCTTCAAAGCGAGCGGGTGAATTGTATGGCTTGCACTTTTTTGGT
TTTAATATGGCTGATGAGGAGTGGAACATTACGCGCTTTTTTTGCATTACCCATGCAGCAAAGCCAAAACCGTTGCGCTT
AAAGGAGGGAACGGCAACGCTTGATAATTCGCATTACAAAACCTCAATTGCTTTTACCTTGCCGAATGAGCAAGGATCGC
TCTTTAAAGCGTTGGCAACCTTTGCGTTGCGCAATATTGATTTAACGAAAATTGAGTCGCGCCCTTTTCGTCAAAAAGCC
TTCGATTATCTTTTTTATGTTGATTTTCTTGGTCATCAGGATGAAGAGCATGTGTGCAATGCTTTAAAGCATTTGCAGGA
ATTTGCAACCATGCTGCATGTGTTGGGCAGTTATGGAGTGGTTGCCGAATGA

Upstream 100 bases:

>100_bases
TATGAAATTTATTGCGAAAACATCAGCCCCAATAGCCCCAATAGCTCTAATAGCTACAAATAGCTACAAATAGCCCACAA
ACCTACAAACCTACAAACCT

Downstream 100 bases:

>100_bases
ATCAGCTTAATTTTTTTGCGGAAGCGGAAGCTACGCCAAAGGGTGAAGTGCCCGTTACCCCAGTAATTCCTGAAAAATCT
GTAACCTTTGCTGAGCTAGC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTNLLTAYQGEPGAYSEIAALRLGTPVPCASFEEVFAAVESERVDYAVIPIENSLGGSIHQNYDLLLQHPVIIEAETFVK
VEHCLLGLPNASLETAGRVLSHPQALAQCRNFFATHPHLKAEVAYDTAGSAKMIAEEKDPTKFALASKRAGELYGLHFFG
FNMADEEWNITRFFCITHAAKPKPLRLKEGTATLDNSHYKTSIAFTLPNEQGSLFKALATFALRNIDLTKIESRPFRQKA
FDYLFYVDFLGHQDEEHVCNALKHLQEFATMLHVLGSYGVVAE

Sequences:

>Translated_283_residues
MTNLLTAYQGEPGAYSEIAALRLGTPVPCASFEEVFAAVESERVDYAVIPIENSLGGSIHQNYDLLLQHPVIIEAETFVK
VEHCLLGLPNASLETAGRVLSHPQALAQCRNFFATHPHLKAEVAYDTAGSAKMIAEEKDPTKFALASKRAGELYGLHFFG
FNMADEEWNITRFFCITHAAKPKPLRLKEGTATLDNSHYKTSIAFTLPNEQGSLFKALATFALRNIDLTKIESRPFRQKA
FDYLFYVDFLGHQDEEHVCNALKHLQEFATMLHVLGSYGVVAE
>Mature_282_residues
TNLLTAYQGEPGAYSEIAALRLGTPVPCASFEEVFAAVESERVDYAVIPIENSLGGSIHQNYDLLLQHPVIIEAETFVKV
EHCLLGLPNASLETAGRVLSHPQALAQCRNFFATHPHLKAEVAYDTAGSAKMIAEEKDPTKFALASKRAGELYGLHFFGF
NMADEEWNITRFFCITHAAKPKPLRLKEGTATLDNSHYKTSIAFTLPNEQGSLFKALATFALRNIDLTKIESRPFRQKAF
DYLFYVDFLGHQDEEHVCNALKHLQEFATMLHVLGSYGVVAE

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=279, Percent_Identity=31.8996415770609, Blast_Score=151, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31466; Mature: 31335

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLLTAYQGEPGAYSEIAALRLGTPVPCASFEEVFAAVESERVDYAVIPIENSLGGSIH
CCCCCEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCC
QNYDLLLQHPVIIEAETFVKVEHCLLGLPNASLETAGRVLSHPQALAQCRNFFATHPHLK
CCCEEEEECCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCE
AEVAYDTAGSAKMIAEEKDPTKFALASKRAGELYGLHFFGFNMADEEWNITRFFCITHAA
EEEEECCCCCCEEEECCCCCCCEEHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCC
KPKPLRLKEGTATLDNSHYKTSIAFTLPNEQGSLFKALATFALRNIDLTKIESRPFRQKA
CCCCEEEECCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCHHHH
FDYLFYVDFLGHQDEEHVCNALKHLQEFATMLHVLGSYGVVAE
HHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TNLLTAYQGEPGAYSEIAALRLGTPVPCASFEEVFAAVESERVDYAVIPIENSLGGSIH
CCCCEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCC
QNYDLLLQHPVIIEAETFVKVEHCLLGLPNASLETAGRVLSHPQALAQCRNFFATHPHLK
CCCEEEEECCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCE
AEVAYDTAGSAKMIAEEKDPTKFALASKRAGELYGLHFFGFNMADEEWNITRFFCITHAA
EEEEECCCCCCEEEECCCCCCCEEHHCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCC
KPKPLRLKEGTATLDNSHYKTSIAFTLPNEQGSLFKALATFALRNIDLTKIESRPFRQKA
CCCCEEEECCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCHHHH
FDYLFYVDFLGHQDEEHVCNALKHLQEFATMLHVLGSYGVVAE
HHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]