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The map label for this gene is surA [H]

Identifier: 78067506

GI number: 78067506

Start: 3173791

End: 3175149

Strand: Reverse

Name: surA [H]

Synonym: Bcep18194_A6037

Alternate gene names: 78067506

Gene position: 3175149-3173791 (Counterclockwise)

Preceding gene: 78067507

Following gene: 78067505

Centisome position: 85.95

GC content: 68.06

Gene sequence:

>1359_bases
ATGAAGAAAACCCTTCGTTTCGCGGCAGTCGTGTCCAGCCTCGCTGCGGCCTCCGCGCTGCTCGCCGCCGCGCCGGCCGC
GGCGCAGGCGCTCGGTTCGCAAGGTGCGCAGCTCGCCGACGAAGTCGTCGCGGTCGTCAACAACGACGTGATCACGGGCC
GCGAACTTGACCAGCGTGCCGGCCTGATCGCGCGCCGGCTGCAGCAGCAGAATGCCCCCGTGCCGCCGACCGACCAGTTG
CGCGCGCAGGTGCTGAACCAGATGGTGCTCGAACGTATCCAGGTGCAGAAGGCCAAGGACGACGGGATCCGCATCGACGA
CGCGACCGTGCAGTCCACGCTGCAGCGTCTCGCGCAGGCGAACGGCATGACGCTCGAGCAGTACCGCGGGCGTCTCGAGG
CGCAAGGCGTGCCCTGGAGCGTCTTCACGAGCGACGCGCGCACCGAACTGATGCTGTCGAAGCTGCGCGAGCGCGAGGTC
GACGGCAAGATCACCGTGTCGGACGCCGAAGTCGCGAACTACATCGCGAGCCAGCGCGGGCCGAACGCGTCGCAGCAGCA
GGACCTGCGCTTCCAGCACATCTTCATCAAGGCGCCGACCAACGCGCCGCAGGCCGACATCGAAGCCGCGCAGAAGAAGG
CTGACGCGTTGCTGCAGCAGGCGAAGTCGGGCGCCGATTTCGAGAAGCTCGCGAAGAACAATTCGGAAGCGAACGACGCG
AAGAAGGGCGGTGACCTCGGCTTCAAGGCGCCGAGCGCGCTGCCGGCGGACGTCGTCGACGCCGCGTCGAAGCTGCGCCC
GGGCCAGGTCAACCCGACGCTGATCCGCGTGCCGGACGGCTTCGAGATCGTGCGTCTCGTCGACCGCCGCCAGAGCCAGG
GCGCGACTGCCGCCGCACCGAAGATCGTCCAGACGCACGTGCGCCACATCCTGCTGCGCGTGGGTGAGGGCAAGTCGGAA
GGCCAGGCGCGCCAGCAACTGGCCGACATCCGCAACCAGGTCGAGGCCGGCGGCGATTTCGCGAAGTTCGCGCGCACCTA
CTCGCAGGACGGTTCGGCGTCGCAGGGCGGCGATCTCGGCTGGATCAGCCCGGGCGAGACCGTGCCGGAATTCGAGCGCG
CGATGAACAACCTGCAGGACGGCCAGATCAGCCAGCCGATCCGTACCGAGTACGGTTACCACCTGATCCAGGTGCTGAGC
CGCCGCGAAGCGGAAGGTTCGGTGCAGCAGCAGATGGATATCGCGCGTCAGGCGATCGGCCAGCGCAAGGCCGAGCAGGC
GTATGCCGACTGGCTGCGCGAGCTGCGCGATTCGTCGTACGTGCAGTACAAGATCGGCGGCGTCGGTCCGGCGAACTGA

Upstream 100 bases:

>100_bases
GCTGCCGCCGCCGCCGCCGCCGATGTCCCGCTTCAGCAACTACGAGTAACGCCGGCTTGTCTGCACCGGTCAGCACGATT
TCAATGGAGTTCCAGTGGCA

Downstream 100 bases:

>100_bases
GCGAGTTTCAGATGACCACGCCCGCGCTGCAGATCGCGATCACGACTGGCGAACCCGCGGGGGTCGGCCCGGAGCTGACC
GTGCAGGCGCTGCGTGATGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKKTLRFAAVVSSLAAASALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRAGLIARRLQQQNAPVPPTDQL
RAQVLNQMVLERIQVQKAKDDGIRIDDATVQSTLQRLAQANGMTLEQYRGRLEAQGVPWSVFTSDARTELMLSKLREREV
DGKITVSDAEVANYIASQRGPNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFEKLAKNNSEANDA
KKGGDLGFKAPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGATAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLADIRNQVEAGGDFAKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLS
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGVGPAN

Sequences:

>Translated_452_residues
MKKTLRFAAVVSSLAAASALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRAGLIARRLQQQNAPVPPTDQL
RAQVLNQMVLERIQVQKAKDDGIRIDDATVQSTLQRLAQANGMTLEQYRGRLEAQGVPWSVFTSDARTELMLSKLREREV
DGKITVSDAEVANYIASQRGPNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFEKLAKNNSEANDA
KKGGDLGFKAPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGATAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLADIRNQVEAGGDFAKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLS
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGVGPAN
>Mature_452_residues
MKKTLRFAAVVSSLAAASALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRAGLIARRLQQQNAPVPPTDQL
RAQVLNQMVLERIQVQKAKDDGIRIDDATVQSTLQRLAQANGMTLEQYRGRLEAQGVPWSVFTSDARTELMLSKLREREV
DGKITVSDAEVANYIASQRGPNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFEKLAKNNSEANDA
KKGGDLGFKAPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGATAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLADIRNQVEAGGDFAKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLS
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGVGPAN

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=372, Percent_Identity=33.3333333333333, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 49015; Mature: 49015

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLRFAAVVSSLAAASALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHH
GLIARRLQQQNAPVPPTDQLRAQVLNQMVLERIQVQKAKDDGIRIDDATVQSTLQRLAQA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NGMTLEQYRGRLEAQGVPWSVFTSDARTELMLSKLREREVDGKITVSDAEVANYIASQRG
CCCCHHHHHCHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCC
PNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFEKLAKNNSEANDA
CCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHH
KKGGDLGFKAPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGATAAAP
HCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHH
KIVQTHVRHILLRVGEGKSEGQARQQLADIRNQVEAGGDFAKFARTYSQDGSASQGGDLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
WISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLSRREAEGSVQQQMDIARQAIG
CCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QRKAEQAYADWLRELRDSSYVQYKIGGVGPAN
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKKTLRFAAVVSSLAAASALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHH
GLIARRLQQQNAPVPPTDQLRAQVLNQMVLERIQVQKAKDDGIRIDDATVQSTLQRLAQA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NGMTLEQYRGRLEAQGVPWSVFTSDARTELMLSKLREREVDGKITVSDAEVANYIASQRG
CCCCHHHHHCHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCC
PNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFEKLAKNNSEANDA
CCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHH
KKGGDLGFKAPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGATAAAP
HCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHH
KIVQTHVRHILLRVGEGKSEGQARQQLADIRNQVEAGGDFAKFARTYSQDGSASQGGDLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
WISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLSRREAEGSVQQQMDIARQAIG
CCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QRKAEQAYADWLRELRDSSYVQYKIGGVGPAN
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA