Click here to switch to the map view.

The map label for this gene is pdxA

Identifier: 78067505

GI number: 78067505

Start: 3172790

End: 3173779

Strand: Reverse

Name: pdxA

Synonym: Bcep18194_A6036

Alternate gene names: 78067505

Gene position: 3173779-3172790 (Counterclockwise)

Preceding gene: 78067506

Following gene: 78067504

Centisome position: 85.91

GC content: 71.52

Gene sequence:

>990_bases
ATGACCACGCCCGCGCTGCAGATCGCGATCACGACTGGCGAACCCGCGGGGGTCGGCCCGGAGCTGACCGTGCAGGCGCT
GCGTGATGCCGCGCAGCGCTGGCCCGACGCACATTTCACCGTGCTCGGCGATGCGGCGCTGCTCGACGCGCGCGCGGCGG
CCGTCGGCGCCGACCGGGCCACGCTGGCCGGCAGCGGGCCGGTGTCGGTCGCGCATCACGCGCTCGCCGTGCCTGTGCAG
GCGGGCCGGCTGGACGCTGCGAACGGCCCGTACGTGCTCGGGTTGCTCGACGCGGCGATCGACGGCGCACTGGCAGGCCG
GTACGACGCGATCGTCACCGCGCCGCTGCAAAAGAGCACGATCAACGATGCGGGCGTGCCGTTCACCGGCCATACCGAAT
ACCTGGCGGAGCGCACGCATACGCCGCGTGTCGTGATGATGCTGGCCGGTACCGGCCACCAGCCGCTGCGCGTCGCGCTC
GCGACCACGCACCTGCCATTGAAGGACGTGTCGGCCGCACTCACGATCGACGGGCTCGTCGAGACGCTTGCGATCATCGA
TCGCGATCTGCGGCGCGACTTCGGCCTGGCCGCACCGCGCATCCTCGTGACGGGCCTGAACCCGCACGCGGGCGAGAACG
GTTATCTCGGCCGCGAGGAGATCGACGTGATCTCGCCGGCGCTGGCCCGCGCGAATGCGCAGGGCATCGACGCGCGCGGC
CCGTATCCGGCCGACACGCTGTTCCAGCCGCGCCATCTCGCCGATGCCGATTGCGTGCTCGCGATGTTCCATGACCAGGG
GCTGCCCGTGCTGAAGTATGCGACGTTCGGCGAGGGCATCAACGTGACGCTCGGGCTGCCGATCATCCGGACGTCGGTCG
ATCACGGCACGGCGCTCGATCTGGCCGGCACGGGCCGCGCGGATCCGGGCAGCATGATCGCCGCGCTCGACACGGCCGTC
ACGATGGCGCGCCATCGCCGCACGGCCTGA

Upstream 100 bases:

>100_bases
CCGAGCAGGCGTATGCCGACTGGCTGCGCGAGCTGCGCGATTCGTCGTACGTGCAGTACAAGATCGGCGGCGTCGGTCCG
GCGAACTGAGCGAGTTTCAG

Downstream 100 bases:

>100_bases
CGCGGCCCGGCTTTACCTCTTTCGTCGTATTTTTCGTTTTACTCAGTCGATGTCGAACAGCAGACAGCACCAAGGCCATT
TCGCGCGCAAGCGCTTCGGG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADRATLAGSGPVSVAHHALAVPVQ
AGRLDAANGPYVLGLLDAAIDGALAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHQPLRVAL
ATTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQGIDARG
PYPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAV
TMARHRRTA

Sequences:

>Translated_329_residues
MTTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADRATLAGSGPVSVAHHALAVPVQ
AGRLDAANGPYVLGLLDAAIDGALAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHQPLRVAL
ATTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQGIDARG
PYPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAV
TMARHRRTA
>Mature_328_residues
TTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADRATLAGSGPVSVAHHALAVPVQA
GRLDAANGPYVLGLLDAAIDGALAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHQPLRVALA
TTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQGIDARGP
YPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAVT
MARHRRTA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=54.2944785276074, Blast_Score=328, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34161; Mature: 34030

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADRA
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCE
TLAGSGPVSVAHHALAVPVQAGRLDAANGPYVLGLLDAAIDGALAGRYDAIVTAPLQKST
EECCCCCHHHHHHEEEEEEECCCEECCCCCEEEEEHHHHHHHHHCCCCCEEEECCCCCCC
INDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHQPLRVALATTHLPLKDVSAALTIDGLV
CCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHEEHHHHH
ETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQGIDARG
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
PYPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALD
CCCCCCCCCCCCCCCCHHEEEEECCCCCCEEEEEECCCCEEEEECCEEEEECCCCCCEEE
LAGTGRADPGSMIAALDTAVTMARHRRTA
ECCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADRA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCE
TLAGSGPVSVAHHALAVPVQAGRLDAANGPYVLGLLDAAIDGALAGRYDAIVTAPLQKST
EECCCCCHHHHHHEEEEEEECCCEECCCCCEEEEEHHHHHHHHHCCCCCEEEECCCCCCC
INDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHQPLRVALATTHLPLKDVSAALTIDGLV
CCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHEEHHHHH
ETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQGIDARG
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
PYPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALD
CCCCCCCCCCCCCCCCHHEEEEECCCCCCEEEEEECCCCEEEEECCEEEEECCCCCCEEE
LAGTGRADPGSMIAALDTAVTMARHRRTA
ECCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA