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The map label for this gene is ribB [H]

Identifier: 78067485

GI number: 78067485

Start: 3150743

End: 3151453

Strand: Reverse

Name: ribB [H]

Synonym: Bcep18194_A6016

Alternate gene names: 78067485

Gene position: 3151453-3150743 (Counterclockwise)

Preceding gene: 78067486

Following gene: 78067479

Centisome position: 85.31

GC content: 68.78

Gene sequence:

>711_bases
ATGTCCTTGATGTCCATTTCGTCGGCACCCGCCGACGCCTTTGCCGATCTCCCGTTGCTGGATTCCGAACCGGTGCCGCC
GCGCATCGCCGCCGCGCTCGAAGCGATGCGCGCAGGCCGTGCGGTCGTGCTGCAGGACGACCACGACCGCGAGAACGAAG
CCGACCTGATCGTTGCCGCCGAGCGCATCACGCCCGAGACGATGGCGCTGCTGATCCGCGAATGCAGCGGCATCGTGTGC
CTGTGCCTGACCGACGACACGGTGCGTGCGCTCGAACTGCCGCCGATGGTGCAGACCAACGAGAGCCGCAACGGCACCGC
GTTCACCGTATCGATCGAGGCACGCGAAGGTGTGCATACGGGCGTGTCGGCGGCCGATCGCGTGACGACGATCCGCGCGG
CCATCGCAGAAGGTGCGAAGCCGCACGACATCGTGCGTCCCGGCCACGTGTTTCCGTTGCGTGCGCAACCGGGCGGCGTG
CTGGCACGCCGCGGTCACACCGAAGGCACGGTCGACCTGTCGATCCTCGCGGGCCTGAAGCCGGCCGGCGTGCTGTGCGA
GCTGATGAATCCGGACGGCACGATGACGCGTGGCGACGATGTCGAGCGTTTCGCGCAACAGCACGGGCTGCCGATGCTGA
CGATCGCGGAACTCGTCGAGTTCCGCGAGGCGCTGGCCGCCGCGCGCGAGCGCTGCTGCGAGCCGGCCTGA

Upstream 100 bases:

>100_bases
GGGCCGCTTCGCCATGCGTGCGAAGCGGGTTGTCGTTCTGTCTGTTTGCAATGCCCTGAAACGTTTTTCGCCCAAATCGT
ATTCGCGAGGAGCGTTTCAC

Downstream 100 bases:

>100_bases
GGGAAAGGAAGGCGGGCGCGTTCGCGCCCGTGGCACGGCGTGCGTGAACCGGCGCACGCCGGATCGGCCCGATCAGCCTG
GTCGGGCCGTCAAAAGCATC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSLMSISSAPADAFADLPLLDSEPVPPRIAAALEAMRAGRAVVLQDDHDRENEADLIVAAERITPETMALLIRECSGIVC
LCLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHTGVSAADRVTTIRAAIAEGAKPHDIVRPGHVFPLRAQPGGV
LARRGHTEGTVDLSILAGLKPAGVLCELMNPDGTMTRGDDVERFAQQHGLPMLTIAELVEFREALAAARERCCEPA

Sequences:

>Translated_236_residues
MSLMSISSAPADAFADLPLLDSEPVPPRIAAALEAMRAGRAVVLQDDHDRENEADLIVAAERITPETMALLIRECSGIVC
LCLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHTGVSAADRVTTIRAAIAEGAKPHDIVRPGHVFPLRAQPGGV
LARRGHTEGTVDLSILAGLKPAGVLCELMNPDGTMTRGDDVERFAQQHGLPMLTIAELVEFREALAAARERCCEPA
>Mature_235_residues
SLMSISSAPADAFADLPLLDSEPVPPRIAAALEAMRAGRAVVLQDDHDRENEADLIVAAERITPETMALLIRECSGIVCL
CLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHTGVSAADRVTTIRAAIAEGAKPHDIVRPGHVFPLRAQPGGVL
ARRGHTEGTVDLSILAGLKPAGVLCELMNPDGTMTRGDDVERFAQQHGLPMLTIAELVEFREALAAARERCCEPA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=207, Percent_Identity=61.3526570048309, Blast_Score=249, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=42.7860696517413, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 25160; Mature: 25029

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMSISSAPADAFADLPLLDSEPVPPRIAAALEAMRAGRAVVLQDDHDRENEADLIVAA
CCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEE
ERITPETMALLIRECSGIVCLCLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHT
CCCCHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCC
GVSAADRVTTIRAAIAEGAKPHDIVRPGHVFPLRAQPGGVLARRGHTEGTVDLSILAGLK
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEEEECCCC
PAGVLCELMNPDGTMTRGDDVERFAQQHGLPMLTIAELVEFREALAAARERCCEPA
CCHHEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLMSISSAPADAFADLPLLDSEPVPPRIAAALEAMRAGRAVVLQDDHDRENEADLIVAA
CCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEE
ERITPETMALLIRECSGIVCLCLTDDTVRALELPPMVQTNESRNGTAFTVSIEAREGVHT
CCCCHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCC
GVSAADRVTTIRAAIAEGAKPHDIVRPGHVFPLRAQPGGVLARRGHTEGTVDLSILAGLK
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEEEECCCC
PAGVLCELMNPDGTMTRGDDVERFAQQHGLPMLTIAELVEFREALAAARERCCEPA
CCHHEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA