Click here to switch to the map view.

The map label for this gene is upp

Identifier: 78067089

GI number: 78067089

Start: 2719901

End: 2720551

Strand: Direct

Name: upp

Synonym: Bcep18194_A5620

Alternate gene names: 78067089

Gene position: 2719901-2720551 (Clockwise)

Preceding gene: 78067072

Following gene: 78067090

Centisome position: 73.63

GC content: 66.21

Gene sequence:

>651_bases
ATGAAACAGGACAGCCGTTTCCCGAATCTCTTCATCACCGATCACCCGCTGATCCAGCACAAGCTCACGCACATGCGCGA
CAAGGACACGTCCACGCGCACGTTCCGAGAGCTGCTGCGCGAAATCACGCTGCTGATGGGTTACGAGATCACCCGCAACC
TACCGATCACGACCAAGCGGGTCGAAACCCCGCTCGTCGAGGTCGACGCGCCGGTGATCGCGGGCAAGAAACTGGCGATC
GTGCCGGTGCTGCGCGCAGGCATCGGGATGTCGGACGGCCTGCTCGACCTGGTTCCGTCCGCGCGCGTCGGCCACATCGG
CGTGTACCGCGCCGACGACCACCGCCCGGTCGAATACCTGGTGCGCCTGCCGGACCTGGAAGACCGCATCTTCATCCTGT
GCGACCCGATGGTCGCGACCGGCTACTCGGCCGTGCACGCGGTCGACGTGCTGAAGCGCCGCAACGTGCCGGCCGCGAAC
ATCATGTTCGTCGCGCTGGTCGCCGCGCCGGAAGGCGTGCAGGTGTTCCAGGACGCGCACCCGGACGTGAAGCTGTTCGT
CGCGTCGCTCGATTCGCACCTGAACGAGCACGCGTACATCGTGCCGGGCCTCGGCGACGCGGGCGACCGCCTGTTCGGCA
CCAAGAACTGA

Upstream 100 bases:

>100_bases
ATCACGCGGCGCGCCTTGGTAAAATTGCGGACATAAGCGCGCGGCCGGCTTGCGCCCGCCCCCGCCCCCGATCCTCTTTT
GCCGCCAAGGCGCCCCCGTC

Downstream 100 bases:

>100_bases
GCATCTGGACGGCCGCGCGGCGCGCGGCCCGGCTCGCGGCGGCCTGCCTGGCCGTTCGGCCATGCGCGGCGGCCCCGATC
CGGCGGTCGCCGCGTGATAA

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEVDAPVIAGKKLAI
VPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAAN
IMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN

Sequences:

>Translated_216_residues
MKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEVDAPVIAGKKLAI
VPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAAN
IMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
>Mature_216_residues
MKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEVDAPVIAGKKLAI
VPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAAN
IMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=32.6732673267327, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=32.6732673267327, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI87082118, Length=203, Percent_Identity=47.2906403940887, Blast_Score=195, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=26.7942583732057, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=26.7942583732057, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321920, Length=192, Percent_Identity=36.4583333333333, Blast_Score=114, Evalue=8e-27,
Organism=Drosophila melanogaster, GI45550449, Length=222, Percent_Identity=33.7837837837838, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573516, Length=222, Percent_Identity=33.7837837837838, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28573514, Length=222, Percent_Identity=33.7837837837838, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28573512, Length=222, Percent_Identity=33.7837837837838, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21358379, Length=171, Percent_Identity=29.8245614035088, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005765 [H]

Pfam domain/function: NA

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 24003; Mature: 24003

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEVDAPVIAGKKLAIVPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYL
CCCCEEEECCCEECCCCEEEHHHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAANIMFVALVAAPEGVQVFQDAH
EECCCCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCHHHEEEEEEEECCCCHHHHHCCC
PDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
CCCEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEVDAPVIAGKKLAIVPVLRAGIGMSDGLLDLVPSARVGHIGVYRADDHRPVEYL
CCCCEEEECCCEECCCCEEEHHHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAANIMFVALVAAPEGVQVFQDAH
EECCCCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCHHHEEEEEEEECCCCHHHHHCCC
PDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
CCCEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA