Click here to switch to the map view.

The map label for this gene is pgl [H]

Identifier: 78066968

GI number: 78066968

Start: 2588092

End: 2589141

Strand: Direct

Name: pgl [H]

Synonym: Bcep18194_A5499

Alternate gene names: 78066968

Gene position: 2588092-2589141 (Clockwise)

Preceding gene: 78066967

Following gene: 78066970

Centisome position: 70.06

GC content: 71.14

Gene sequence:

>1050_bases
ATGCCGAACACTGACCGCCCGACCGTCGTCGTCTCGAATGCCGCAGACGGCGATCTCTCCACCTTCTCGCTCGCGGCCGA
CGGCACGCTTGCGCCGCTCGCCCGCTATCCCGCAGCCGACGTCGCGATGCCGATCGCCGTGCAGGCCGACCGGGCTCGCC
TCTACGTCGCGACGCGCGGTGAACAACCGACGATCGTCGCGTTCCGCGTCGTGCCGGCCACCGGCGCGCTCGTGCGCATC
GGCACGACCGCGATCGACGCGAGCCATGCGTACCTGTCGCTCGACCGCAGCGGCCGCTGGCTGCTCGGCGCGTCTTACGG
CGGGAACTCGCTGAGTCTCTACGACGCCGCGCACGTGCGCGACGGCGACGGCACGCCGTTGCAAGTCGCGAGCGGCATCG
CGAACGCGCACTCGGTGATCGTGTCGCCGGACAACCGTTTCGCGTACGTCAGTTCACTCGGCTCGGATCGCGTGTTCAGC
TTCGCGCTCGTCGAAGACGCGGCCGGCCTGCGCGCGCTCGAACACGGCGAAACGCGCGTGCCGACCGGGTTCGGCCCGCG
TCACCTGCAATTTGCTGATGACGGCCGTGCGCTCGTCGTCGTCAGCGAATTCGAGGCCACGCTCGCGACGTTCACGCGCG
ATCCCGACACCGGCCGGCTCGGCGATGCGCATGTCAGCGCGCGCCATCCCGCCGTCGCCGAACTCGCGCAAGGCCATGCG
CGGCCGCCCGCGCCCACCGAACCGTCCGTCTGGGCCGCCGACCTGCACCTGACGCCCGACGAGCGTTTCGCCTATGTCAG
CGAACGCACGTCAAGCCGCCTGCTCTGCTATCGCCGCGGCGAAGACGGCACGTTCGAACCCGCGCACGCGACCGCCACCG
AGACGCAGCCGCGCGGGTTCGCCATCGACCCGTCGGGGCGCTGGCTCGTCGCCTGCGGCGAACAGTCGGAATACGTATCG
GTGTATGCGATCGCGCCGGACGACGGCGCGCTGTCGCCGCACGCGCGCGTGCCGGGCGGACGCGGTGCGAACTGGGTCGC
GATCGTCTGA

Upstream 100 bases:

>100_bases
GCCGCGGTCGCCGCGCTGTTCGCGCGCACGCACCGGCGTAGCGATCCGCCGCGCGGCCTGCCGGCCGACGAATCCTTCAC
GAACGCTTCGATGCTCCGCC

Downstream 100 bases:

>100_bases
TGAAGTCGTGGCGCACGGAACCTGACTCGGCAGGCCCGCCATGCAGGCCGGTGCGGCCCCGCGTTCAGCGCCGCTCGCTC
GGCGCGACGCCCGTCCAGCG

Product: 3-carboxymuconate cyclase-like

Products: NA

Alternate protein names: 6-P-gluconolactonase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPNTDRPTVVVSNAADGDLSTFSLAADGTLAPLARYPAADVAMPIAVQADRARLYVATRGEQPTIVAFRVVPATGALVRI
GTTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAAHVRDGDGTPLQVASGIANAHSVIVSPDNRFAYVSSLGSDRVFS
FALVEDAAGLRALEHGETRVPTGFGPRHLQFADDGRALVVVSEFEATLATFTRDPDTGRLGDAHVSARHPAVAELAQGHA
RPPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLCYRRGEDGTFEPAHATATETQPRGFAIDPSGRWLVACGEQSEYVS
VYAIAPDDGALSPHARVPGGRGANWVAIV

Sequences:

>Translated_349_residues
MPNTDRPTVVVSNAADGDLSTFSLAADGTLAPLARYPAADVAMPIAVQADRARLYVATRGEQPTIVAFRVVPATGALVRI
GTTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAAHVRDGDGTPLQVASGIANAHSVIVSPDNRFAYVSSLGSDRVFS
FALVEDAAGLRALEHGETRVPTGFGPRHLQFADDGRALVVVSEFEATLATFTRDPDTGRLGDAHVSARHPAVAELAQGHA
RPPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLCYRRGEDGTFEPAHATATETQPRGFAIDPSGRWLVACGEQSEYVS
VYAIAPDDGALSPHARVPGGRGANWVAIV
>Mature_348_residues
PNTDRPTVVVSNAADGDLSTFSLAADGTLAPLARYPAADVAMPIAVQADRARLYVATRGEQPTIVAFRVVPATGALVRIG
TTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAAHVRDGDGTPLQVASGIANAHSVIVSPDNRFAYVSSLGSDRVFSF
ALVEDAAGLRALEHGETRVPTGFGPRHLQFADDGRALVVVSEFEATLATFTRDPDTGRLGDAHVSARHPAVAELAQGHAR
PPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLCYRRGEDGTFEPAHATATETQPRGFAIDPSGRWLVACGEQSEYVSV
YAIAPDDGALSPHARVPGGRGANWVAIV

Specific function: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate [H]

COG id: COG2706

COG function: function code G; 3-carboxymuconate cyclase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cycloisomerase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786983, Length=352, Percent_Identity=30.9659090909091, Blast_Score=161, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022528
- InterPro:   IPR019405
- InterPro:   IPR011045
- InterPro:   IPR015943 [H]

Pfam domain/function: PF10282 DUF2394 [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 36864; Mature: 36733

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTDRPTVVVSNAADGDLSTFSLAADGTLAPLARYPAADVAMPIAVQADRARLYVATRG
CCCCCCCEEEEECCCCCCCEEEEEECCCCCHHHHHCCCCCCEEEEEEEECCEEEEEEECC
EQPTIVAFRVVPATGALVRIGTTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAAHVR
CCCEEEEEEEECCCCEEEEEECEEEECCEEEEEECCCCCEEEEECCCCCEEEEEEEEEEE
DGDGTPLQVASGIANAHSVIVSPDNRFAYVSSLGSDRVFSFALVEDAAGLRALEHGETRV
CCCCCEEHHHHCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEECCCCCCEEHHCCCCCC
PTGFGPRHLQFADDGRALVVVSEFEATLATFTRDPDTGRLGDAHVSARHPAVAELAQGHA
CCCCCCCEEEEECCCCEEEEEECCCEEEHHEECCCCCCCCCCCEECCCCCHHHHHHCCCC
RPPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLCYRRGEDGTFEPAHATATETQPRGF
CCCCCCCCCEEEEEEEECCHHHEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCE
AIDPSGRWLVACGEQSEYVSVYAIAPDDGALSPHARVPGGRGANWVAIV
EECCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure 
PNTDRPTVVVSNAADGDLSTFSLAADGTLAPLARYPAADVAMPIAVQADRARLYVATRG
CCCCCCEEEEECCCCCCCEEEEEECCCCCHHHHHCCCCCCEEEEEEEECCEEEEEEECC
EQPTIVAFRVVPATGALVRIGTTAIDASHAYLSLDRSGRWLLGASYGGNSLSLYDAAHVR
CCCEEEEEEEECCCCEEEEEECEEEECCEEEEEECCCCCEEEEECCCCCEEEEEEEEEEE
DGDGTPLQVASGIANAHSVIVSPDNRFAYVSSLGSDRVFSFALVEDAAGLRALEHGETRV
CCCCCEEHHHHCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEECCCCCCEEHHCCCCCC
PTGFGPRHLQFADDGRALVVVSEFEATLATFTRDPDTGRLGDAHVSARHPAVAELAQGHA
CCCCCCCEEEEECCCCEEEEEECCCEEEHHEECCCCCCCCCCCEECCCCCHHHHHHCCCC
RPPAPTEPSVWAADLHLTPDERFAYVSERTSSRLLCYRRGEDGTFEPAHATATETQPRGF
CCCCCCCCCEEEEEEEECCHHHEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCE
AIDPSGRWLVACGEQSEYVSVYAIAPDDGALSPHARVPGGRGANWVAIV
EECCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA