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The map label for this gene is dctS [H]

Identifier: 78066913

GI number: 78066913

Start: 2516268

End: 2518784

Strand: Direct

Name: dctS [H]

Synonym: Bcep18194_A5444

Alternate gene names: 78066913

Gene position: 2516268-2518784 (Clockwise)

Preceding gene: 78066909

Following gene: 78066914

Centisome position: 68.12

GC content: 65.79

Gene sequence:

>2517_bases
ATGTTGACCGATCGGCTTTTCGCACGCTCGGCGCGACCGTCGGGCCCGCCGGCGGAGTCGCAGCCGTCCCGTTGGCACCA
CGGACCGTGGTGGTCCAATTCCTATTTGCTGACGCCCCTGCTGTCGATCCTGGTGTTCCTGGTGGTGATGAGTCTCATCC
TGTGGAGCCTCAATCGCCGCGAACAGCAGCAGCAGGAAGACACCCTCTTCCGTAACGTTGCGTGGGCGCAGCAACAGATC
CGCCTGTCGATGACGGGGGCGCAGGAACAGCTCCAGGCCCTCTCCCGCGATCTCGCGTCCGGCCGCCTCGACCAGAACGC
GTTCCAGATGGCCGTCGCGGACGTGATGCAAACGCATCCGGAAATCCTCTACCTGAACTGGTACACGTCGCCCGGCGTGC
AGCGCTGGCCGACCGTGCATCCGCCGCTGCTCGGCCAGCGGCTCGCGAAGCCCGGCGAAGCGCAGATGCAGGATGCCGTG
CGCGGCGCGTACGACGAGGCGCGCAGCACGCGCCGCCAGGCCTATTCGCCGCTGATCTACGACGACTTCGGCAACGGCTT
CATCACGCTGCAGACACCGGTGATGCGCGGCGACCGCGAGTACCTCGGCTCGATCGCGGCGGTGTTCTCGGTCGAAGGCA
TCCTGAAGCACGACATCCCGCAGGAACTGTCGTCGAAGTACAAGATTTCGATCACCGACGCGAACAACCGCGAGCTGTCG
TCCACGTCGACGCGCCCGCGCCTGCCGCGCGACTCGCACTACGACCTGCCGCTCGATCCGCCCGGCCAGGGGCTGACCGT
GCGCGTGTACGCGTTCCCGCAGCTCACGAACCTGACCAACAACACGCTCGTGTGGCTCGTCGCGGGCCTGTCGTGCTTCG
TGCTGTGGAGCCTCTGGAGCCTGTGGAAGCACACGCGTCAGCGCTTCGAGGCGCAGCAGGCGCTGTACGCGGAAGCGTTC
TTCCGCCGTGCGATGGAAAATTCCGTGCTGATCGGCATGCGCGTGCTCGACATGCACGGCCGCATCACGCACGTGAACCC
CGCCTTCTGCCGGATGACGGGCTGGGACGAAACCGACCTCGTCGGCAAGGTCGCGCCGTTCCCGTACTGGCCGCGTGACG
CGTACCCGGAAATGCAGCGCCAGCTCGACATGACGCTGCGCGGCAAGGCGCCGAGCTCGGGCTTCGAGCTGCGCGTGCGG
CGCAAGAACGGCACGCTGTTCCATGCGCGCCTGTACGTGTCGCCGCTGATCGACAGCTCGGGCCGCCAGACCGGCTGGAT
GTCGTCGATGACCGACATCACCGAGCCGAAGCGTGCGCGCGAGGAACTCGCGGCCGCGCACGAGCGCTTCACGACGGTGC
TCGAAAGCCTCGACGCCGCGGTGTCGGTGCTGGCCGCCGACGAAGCCGAGCTGCTGTTCGCGAACCGCTACTACCGCCAC
CTGTTCGGCATTCGCCCGGACGGCCATCTCGAACTGTCGGGCGGCGGCTTCGACCGCGCGCAGGCCTCGTCAGACTCGAT
CGACATGGTCGACGCGTTCGCAGGCCTGCCGGCCGCCGCGCTGACGAGCAGCACCGCCGATGCGCAAGAGGTGTACGTCG
AGAGCATCCAGAAGTGGTTCGAGGTGCGCCGCCAGTACATCCAGTGGGTGGACGGCCACCTCGCGCAAATGCAGATCGCG
ACCGACATCACGACCCGCAAGAAGGCACAGGAACTCGCGCACCAGCAGGAAGAGAAGCTGCAGTTCACGAGCCGATTGAT
GACGATGGGTGAAATGGCGTCGTCGATTGCTCACGAATTGAATCAGCCGCTCGCCGCGATCAACAACTACTGCTCGGGCA
CGCTCGCACTCGTGAAGAGCGGCCGCGGCACGCCGGAGACGCTGCAGCCCGCGCTGGAAAAGACCGCGCAACAGGCGCTG
CGCGCGGGGATGATCGTCAAGCGGATCCGCGAATTCGTGAAGCGCAGCGAGCCGAAGCGCCAGCCGGCGCGGGTCGCGGA
CATCGTCGCCGACGCGGTCGGGCTCGCCGAAATCGAGGCCAGGAAGCGCAGGATCCGGATCGTCACGGAAATCCTCGCAA
GAATGCCTATTATTTATGTCGACCCCGTGCTGATCGAGCAGGTGCTCGTGAACCTGATGAAGAACGCGGCCGAAGCGATG
GCCGACGTGAAGCCGGCGTCGGTGGACGGCGTGATCCGCGTCGTCGCCGACATCGAGGCGGGCTTCGTCGACATCCGCGT
GATCGACCAGGGCCCGGGCGTCGACGAAGCGACCGCCGAGCGCCTGTTTGAACCGTTTTACAGCACCAAGTCCGATGGCA
TGGGCATGGGGCTGAATATCTGTCGTTCGATTATCGAATCGCATCGGGGGCGTCTGTGGGTGGTCAACAACGTCGAGCCG
GATGGCCGCATATCCGGCGCAACGTTCCACTGCAGCTTGCCCATTGGGGAACCCGCTGATCTCGGCCAAGGGGGGCGCGA
GGCATCGGCATCACATACCGTTACGGGAGAACTATGA

Upstream 100 bases:

>100_bases
ATTTCGGGGCTCTCCGGCGCGTCTCGGCTGAACAAATCCGTTTCCGTTCAACATATCCGGTATAGGTTTTCCATGTATTG
CGCTGCGCTACAATCGTCGA

Downstream 100 bases:

>100_bases
ATAGCCCTGTCACCACCACTCAGGAAACCGTCTTTGTCGTTGACGACGACGAGGCCGTACGGGACTCGCTGCGCTGGCTG
CTGGAGGCGAACGGCTATCG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 838; Mature: 838

Protein sequence:

>838_residues
MLTDRLFARSARPSGPPAESQPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSLNRREQQQQEDTLFRNVAWAQQQI
RLSMTGAQEQLQALSRDLASGRLDQNAFQMAVADVMQTHPEILYLNWYTSPGVQRWPTVHPPLLGQRLAKPGEAQMQDAV
RGAYDEARSTRRQAYSPLIYDDFGNGFITLQTPVMRGDREYLGSIAAVFSVEGILKHDIPQELSSKYKISITDANNRELS
STSTRPRLPRDSHYDLPLDPPGQGLTVRVYAFPQLTNLTNNTLVWLVAGLSCFVLWSLWSLWKHTRQRFEAQQALYAEAF
FRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDETDLVGKVAPFPYWPRDAYPEMQRQLDMTLRGKAPSSGFELRVR
RKNGTLFHARLYVSPLIDSSGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYYRH
LFGIRPDGHLELSGGGFDRAQASSDSIDMVDAFAGLPAAALTSSTADAQEVYVESIQKWFEVRRQYIQWVDGHLAQMQIA
TDITTRKKAQELAHQQEEKLQFTSRLMTMGEMASSIAHELNQPLAAINNYCSGTLALVKSGRGTPETLQPALEKTAQQAL
RAGMIVKRIREFVKRSEPKRQPARVADIVADAVGLAEIEARKRRIRIVTEILARMPIIYVDPVLIEQVLVNLMKNAAEAM
ADVKPASVDGVIRVVADIEAGFVDIRVIDQGPGVDEATAERLFEPFYSTKSDGMGMGLNICRSIIESHRGRLWVVNNVEP
DGRISGATFHCSLPIGEPADLGQGGREASASHTVTGEL

Sequences:

>Translated_838_residues
MLTDRLFARSARPSGPPAESQPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSLNRREQQQQEDTLFRNVAWAQQQI
RLSMTGAQEQLQALSRDLASGRLDQNAFQMAVADVMQTHPEILYLNWYTSPGVQRWPTVHPPLLGQRLAKPGEAQMQDAV
RGAYDEARSTRRQAYSPLIYDDFGNGFITLQTPVMRGDREYLGSIAAVFSVEGILKHDIPQELSSKYKISITDANNRELS
STSTRPRLPRDSHYDLPLDPPGQGLTVRVYAFPQLTNLTNNTLVWLVAGLSCFVLWSLWSLWKHTRQRFEAQQALYAEAF
FRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDETDLVGKVAPFPYWPRDAYPEMQRQLDMTLRGKAPSSGFELRVR
RKNGTLFHARLYVSPLIDSSGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYYRH
LFGIRPDGHLELSGGGFDRAQASSDSIDMVDAFAGLPAAALTSSTADAQEVYVESIQKWFEVRRQYIQWVDGHLAQMQIA
TDITTRKKAQELAHQQEEKLQFTSRLMTMGEMASSIAHELNQPLAAINNYCSGTLALVKSGRGTPETLQPALEKTAQQAL
RAGMIVKRIREFVKRSEPKRQPARVADIVADAVGLAEIEARKRRIRIVTEILARMPIIYVDPVLIEQVLVNLMKNAAEAM
ADVKPASVDGVIRVVADIEAGFVDIRVIDQGPGVDEATAERLFEPFYSTKSDGMGMGLNICRSIIESHRGRLWVVNNVEP
DGRISGATFHCSLPIGEPADLGQGGREASASHTVTGEL
>Mature_838_residues
MLTDRLFARSARPSGPPAESQPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSLNRREQQQQEDTLFRNVAWAQQQI
RLSMTGAQEQLQALSRDLASGRLDQNAFQMAVADVMQTHPEILYLNWYTSPGVQRWPTVHPPLLGQRLAKPGEAQMQDAV
RGAYDEARSTRRQAYSPLIYDDFGNGFITLQTPVMRGDREYLGSIAAVFSVEGILKHDIPQELSSKYKISITDANNRELS
STSTRPRLPRDSHYDLPLDPPGQGLTVRVYAFPQLTNLTNNTLVWLVAGLSCFVLWSLWSLWKHTRQRFEAQQALYAEAF
FRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDETDLVGKVAPFPYWPRDAYPEMQRQLDMTLRGKAPSSGFELRVR
RKNGTLFHARLYVSPLIDSSGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYYRH
LFGIRPDGHLELSGGGFDRAQASSDSIDMVDAFAGLPAAALTSSTADAQEVYVESIQKWFEVRRQYIQWVDGHLAQMQIA
TDITTRKKAQELAHQQEEKLQFTSRLMTMGEMASSIAHELNQPLAAINNYCSGTLALVKSGRGTPETLQPALEKTAQQAL
RAGMIVKRIREFVKRSEPKRQPARVADIVADAVGLAEIEARKRRIRIVTEILARMPIIYVDPVLIEQVLVNLMKNAAEAM
ADVKPASVDGVIRVVADIEAGFVDIRVIDQGPGVDEATAERLFEPFYSTKSDGMGMGLNICRSIIESHRGRLWVVNNVEP
DGRISGATFHCSLPIGEPADLGQGGREASASHTVTGEL

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=27.6150627615063, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=27.3408239700375, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=25.1937984496124, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=257, Percent_Identity=24.9027237354086, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 93837; Mature: 93837

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDRLFARSARPSGPPAESQPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSLNRR
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQQQQEDTLFRNVAWAQQQIRLSMTGAQEQLQALSRDLASGRLDQNAFQMAVADVMQTHP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
EILYLNWYTSPGVQRWPTVHPPLLGQRLAKPGEAQMQDAVRGAYDEARSTRRQAYSPLIY
CEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
DDFGNGFITLQTPVMRGDREYLGSIAAVFSVEGILKHDIPQELSSKYKISITDANNRELS
ECCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCCCC
STSTRPRLPRDSHYDLPLDPPGQGLTVRVYAFPQLTNLTNNTLVWLVAGLSCFVLWSLWS
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHH
LWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDETDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCHHHEEECCCCCHHH
VGKVAPFPYWPRDAYPEMQRQLDMTLRGKAPSSGFELRVRRKNGTLFHARLYVSPLIDSS
CCCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCEEEEEECCCCEEEEEEEEEHHHCCC
GRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYYRH
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LFGIRPDGHLELSGGGFDRAQASSDSIDMVDAFAGLPAAALTSSTADAQEVYVESIQKWF
HHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHH
EVRRQYIQWVDGHLAQMQIATDITTRKKAQELAHQQEEKLQFTSRLMTMGEMASSIAHEL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQPLAAINNYCSGTLALVKSGRGTPETLQPALEKTAQQALRAGMIVKRIREFVKRSEPKR
CCHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QPARVADIVADAVGLAEIEARKRRIRIVTEILARMPIIYVDPVLIEQVLVNLMKNAAEAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHH
ADVKPASVDGVIRVVADIEAGFVDIRVIDQGPGVDEATAERLFEPFYSTKSDGMGMGLNI
HCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
CRSIIESHRGRLWVVNNVEPDGRISGATFHCSLPIGEPADLGQGGREASASHTVTGEL
HHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTDRLFARSARPSGPPAESQPSRWHHGPWWSNSYLLTPLLSILVFLVVMSLILWSLNRR
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EQQQQEDTLFRNVAWAQQQIRLSMTGAQEQLQALSRDLASGRLDQNAFQMAVADVMQTHP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
EILYLNWYTSPGVQRWPTVHPPLLGQRLAKPGEAQMQDAVRGAYDEARSTRRQAYSPLIY
CEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
DDFGNGFITLQTPVMRGDREYLGSIAAVFSVEGILKHDIPQELSSKYKISITDANNRELS
ECCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCCCC
STSTRPRLPRDSHYDLPLDPPGQGLTVRVYAFPQLTNLTNNTLVWLVAGLSCFVLWSLWS
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHH
LWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDETDL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCHHHEEECCCCCHHH
VGKVAPFPYWPRDAYPEMQRQLDMTLRGKAPSSGFELRVRRKNGTLFHARLYVSPLIDSS
CCCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCEEEEEECCCCEEEEEEEEEHHHCCC
GRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADEAELLFANRYYRH
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LFGIRPDGHLELSGGGFDRAQASSDSIDMVDAFAGLPAAALTSSTADAQEVYVESIQKWF
HHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHH
EVRRQYIQWVDGHLAQMQIATDITTRKKAQELAHQQEEKLQFTSRLMTMGEMASSIAHEL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQPLAAINNYCSGTLALVKSGRGTPETLQPALEKTAQQALRAGMIVKRIREFVKRSEPKR
CCHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QPARVADIVADAVGLAEIEARKRRIRIVTEILARMPIIYVDPVLIEQVLVNLMKNAAEAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHH
ADVKPASVDGVIRVVADIEAGFVDIRVIDQGPGVDEATAERLFEPFYSTKSDGMGMGLNI
HCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHH
CRSIIESHRGRLWVVNNVEPDGRISGATFHCSLPIGEPADLGQGGREASASHTVTGEL
HHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]