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The map label for this gene is clpX

Identifier: 78066692

GI number: 78066692

Start: 2278218

End: 2279489

Strand: Reverse

Name: clpX

Synonym: Bcep18194_A5223

Alternate gene names: 78066692

Gene position: 2279489-2278218 (Counterclockwise)

Preceding gene: 78066693

Following gene: 78066691

Centisome position: 61.71

GC content: 61.32

Gene sequence:

>1272_bases
ATGGCGGACAAAAAAGGTTCGAACAGCGAGAAGCTGTTGTATTGCTCGTTTTGCGGGAAGAGCCAGCATGAGGTGAAAAA
ACTCATCGCGGGCCCGTCGGTGTTCATCTGCGATGAGTGCATCGACCTCTGCAACGAAATCATTCGCGACGAGGCGGCTG
CCGCCGGCGTCGAGGCCAGCCTGTCCCGGTCGGATCTCCCGAGCCCGCAGGAAATTCGCGACATCCTCGATCAGTACGTG
ATCGGCCAGGAGCGCGCGAAGAAGATCCTCGCGGTGGCCGTGTACAACCACTACAAGCGCCTCAAGCATCTCGACAAGAA
GGACGACGTCGAGCTGTCGAAGAGCAACATCCTGCTGATCGGCCCGACGGGCTCCGGCAAGACGCTGCTCGCGCAGACGC
TCGCGCGGTTGCTCAACGTGCCGTTCGTGATCGCCGATGCGACGACGCTGACCGAAGCCGGCTACGTCGGCGAGGACGTC
GAGAACATCATCCAGAAGCTGTTGCAGAACTGCAACTACGAGGTCGACAAGGCCCAGCGCGGGATCGTCTACATCGACGA
AATCGACAAGATCAGCCGCAAGTCGGACAACCCGTCGATCACGCGCGACGTGTCGGGCGAGGGTGTCCAGCAGGCACTGC
TGAAGCTCGTCGAGGGCACGATGGCGTCGGTGCCGCCGCAGGGTGGCCGCAAGCATCCGAACCAGGATTTCATCCAGGTC
GACACGACCAACATCCTGTTCATCTGCGGCGGTGCATTCGACGGCCTCGAGAAGGTGATCACCGATCGTACCGAGAAAAC
CGGTATCGGCTTCGGCGCGACGGTCAAGAGCAAGCAGGAACGCGACGCGGGCGAAGTGCTGCGCGAAACGGAACCGGAAG
ACCTGATCAAATTCGGTCTGATCCCCGAATTGATCGGCCGCCTGCCGGTGGTCGCGACGCTCGGCAAGCTCGATGAAGCC
GCGCTGATGAAGATCCTGGTCGAGCCGAAGAACGCGCTCGTCAAGCAGTATCACAAGCTGTTCGCGATGGAGCGCGTCGA
GCTGGAGATCCGGCCGGGCGCACTGCAGGCAGTCGCCCGCAAGGCGATCCGCCGCAAGACCGGCGCGCGCGGTTTGCGTT
CGATCATCGAACAGGCCTTGCTCGACGTGATGTACGAGCTGCCGACGATGAAAGGGGTCAGCAAAGTCATCATCGACGAG
AACGTCATCGATGGAGACGGCAAGCCTTTGCTGATCTACGAGGACACGCCGAAGGTGGCGGGTTCGAACTGA

Upstream 100 bases:

>100_bases
CTGCGGCAAGCGCATCCAGCCGGCTCCGGTCGCGCCCTAGGCGCGGCGCTCGGAGCATTCGGCGTATCATGTCATTTACC
TGTCCGGAGGCTCTACATTC

Downstream 100 bases:

>100_bases
CCGGCTTGCCGACGATGTTCTGCGAAAAAGGCCGTTCATGAGACCGTGGGCGGCTTTTTTTCGTTTATCTTGTGGGTAAC
TCTGACTCGACACGCGGTGG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSRSDLPSPQEIRDILDQYV
IGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
DTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLRETEPEDLIKFGLIPELIGRLPVVATLGKLDEA
ALMKILVEPKNALVKQYHKLFAMERVELEIRPGALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTMKGVSKVIIDE
NVIDGDGKPLLIYEDTPKVAGSN

Sequences:

>Translated_423_residues
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSRSDLPSPQEIRDILDQYV
IGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
DTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLRETEPEDLIKFGLIPELIGRLPVVATLGKLDEA
ALMKILVEPKNALVKQYHKLFAMERVELEIRPGALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTMKGVSKVIIDE
NVIDGDGKPLLIYEDTPKVAGSN
>Mature_422_residues
ADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSRSDLPSPQEIRDILDQYVI
GQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVE
NIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQVD
TTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLRETEPEDLIKFGLIPELIGRLPVVATLGKLDEAA
LMKILVEPKNALVKQYHKLFAMERVELEIRPGALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTMKGVSKVIIDEN
VIDGDGKPLLIYEDTPKVAGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=333, Percent_Identity=51.3513513513513, Blast_Score=317, Evalue=2e-86,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=74.2168674698795, Blast_Score=621, Evalue=1e-179,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=46, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988663, Length=405, Percent_Identity=41.9753086419753, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI71982908, Length=297, Percent_Identity=47.1380471380471, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=297, Percent_Identity=47.1380471380471, Blast_Score=268, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=43.7751004016064, Blast_Score=187, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6319704, Length=447, Percent_Identity=38.7024608501119, Blast_Score=277, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24648291, Length=324, Percent_Identity=45.679012345679, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24648289, Length=324, Percent_Identity=45.679012345679, Blast_Score=282, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46405; Mature: 46274

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEAS
CCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHH
LSRSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLI
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
GPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQR
ECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHCC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
DTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLRETEPEDLIKFGL
ECCEEEEEECCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHCCHHHHHHCCCHHHHHHHHH
IPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYHKLFAMERVELEIRPGALQAVAR
HHHHHCCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHHH
KAIRRKTGARGLRSIIEQALLDVMYELPTMKGVSKVIIDENVIDGDGKPLLIYEDTPKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEECCCCCEEEEECCCCCCC
GSN
CCC
>Mature Secondary Structure 
ADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEAS
CCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHH
LSRSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLI
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
GPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQR
ECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHCC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
DTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLRETEPEDLIKFGL
ECCEEEEEECCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHCCHHHHHHCCCHHHHHHHHH
IPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYHKLFAMERVELEIRPGALQAVAR
HHHHHCCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHHH
KAIRRKTGARGLRSIIEQALLDVMYELPTMKGVSKVIIDENVIDGDGKPLLIYEDTPKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEECCCCCEEEEECCCCCCC
GSN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA