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The map label for this gene is ppiD [H]

Identifier: 78066690

GI number: 78066690

Start: 2272824

End: 2274758

Strand: Reverse

Name: ppiD [H]

Synonym: Bcep18194_A5221

Alternate gene names: 78066690

Gene position: 2274758-2272824 (Counterclockwise)

Preceding gene: 78066691

Following gene: 78066688

Centisome position: 61.58

GC content: 65.27

Gene sequence:

>1935_bases
ATGCTCGATTTCTTCCGTAATCACCAGCGCCTGATGATGGCGCTCCTGCTCCTGATCGTGTTGCCGGGGCTGGGTTTCGT
CGGGATCCAAGGCTTCCGCGGCTTCTTCGACGATAGCGCGAACGTCGCGGCAGTCAACGGGCACAAGATCACGCGGGTCG
AATTCGACGGCGCGTTCCGCCAGCAGATCGACCAGGCGCGTCAGGCGCTCGGCGGGCAGTTCGACATCAAGATGTTCGAT
ACGCCCGAGCACCGCAAGCAAGTGCTCGACGGCCTGATCCAGCAACGCGTGCTGGCCGACGAGACTCAACGTCTGCACCT
GACCGCATCCGACAACGCCGTGCGCGACGCGCTGATGAGCGACCCGATGATCGCGTCGCTGAAGAAGCCCGACGGCTCGA
TCGACGTCGAACGCTATGCGCAACTGCTGTCGTTCCAGGGAATGACGCCCGAGCAGTATCAGGAACGCGTGCGCTACAGC
CTCTCGCTGCAACAGATTCCGGCCAGCATCGTATCGAGCGCATTCACGCCGAAGAGCCTTGCGCAACGCCTGTCCGAACT
CGCCGCGCAGCAGCGCGAAGTGCAGGCGCTTGTGCTGAAGACGAGCGACTTCGCAGCGAAGGTCCAGCCGACCGATGCGC
AACTCGCCGCGTACTATGACGCGCACAAGCAAAGCTTCGCGACGCCGGAGACCGCGACGATCCAGTACCTCGTCTATTCG
CCGGCCGCAGCGGCTGCGAGCGCACAGCCGACCGATGCGGACATCAAGAAGTTCTACGACGACAACCCGACGCACTTCCG
CACCGAAGCGCAGGTTCGCGTGAGCCACATCTTCATCGCTGCGCCGGGCAGCGCAAGCGCGGCCGACAAGACGGCAGCGA
AGACGAAGGCCGAGCAGTTGCTGGCCGACGTGAAGGCGCATCCCGACCAGTTCGCGCAGGTCGCGCAGAAGAGCTCGCAG
GACGCACCGTCGGCGGCGAAGGGCGGCGACCTCGGCTTCATCACGCGCGGCTCGACGGCGGGCGGCAAGGCGTTCGACGA
TGCCGCGTTCGCGCTCAAGCAGGGTGACGTGAGCGGTGTCGTGCAGTCGGATCTGGGCTTCCACATCCTGAAGGCAACGG
AAGTGAAGCCGGCGGCCGTCAAGCCGTTCGCTGACGTGAAGGACCAGATCGCCGCGGAACTGAAGCAGCAGTACGCATCG
AAGGCGTTCACGGACAACGCGGAAGGCTTCACGTCCACCGTCTACGAAAAGGCGAAGACGCTGCAGCCTGCCGCGGACAA
GTACAAGCTGACGATCCAGACGGCCACCGTCACGCCGACGCCGAATCCGCAGCTGCCGCCGACGAGCCCGCTGAACAATC
CGAAGTTCCTGGCCGCCGTGTTCGCCAACGACTCGGTGAAGAGCCAGAACAACACGCAGGCGATCGACATCGGCAACAAC
ACGCTGATCTCGGCGCGCGTGACCGACTACAAGCCGGCTGCCGTGCCCGCGCTCGACGCGATCAAGGACGTCGTGCGCCA
GAAGGTCGTCGCCGAGCAGGCTGCTGAACTCGCGAAGAAGGACGGCGTGGCGAAGCTCGCCGAACTGCAGAAGTCGAAGT
CGGCCGACGGGTTCGCCGCCGCGCAGAAGGTCTCGCGCACGCAGTCGCAGGGCCTGACGCCGGCTGCGCTGAGCGCTGTG
TACAAGGTCGACGCGAAGACGCTGCCCGCGTACGTCGGTGTCGATCTCGGCGCAGACGGCTACGCGATCTACCGTGTGAA
CGCGGTGATCCCGGGTTCGGCGGTCGATCCGCAGCAACTGGCGGCCGCGCAGCAGCAGATGGCGCAGGTCGACGCGCAAA
GCGAAGGCGAAGCGTATCTCGCCGCGCTGCGCGATCGCTCGAAGGTGAAGCTGTACGGCTCGACGGCCGGCCAGTCGCAG
GACGGCGACAACTGA

Upstream 100 bases:

>100_bases
TTGCTTGCCGTGTCGTACTCGCCCGCAGCACGTCTGCTTTTCTCCCGTCCCACCCCGTATGTTGTAATATCGGTCGTTTT
GTCCAATTTTCCCGTCACGC

Downstream 100 bases:

>100_bases
GCGTCGTTTCGCACGCAACAAAAAAAGCCCCGCTTCATGCGGGGCTTTTTGTTTTCCGGGCGGGGCGGTGGCGTCAGCCG
CGCGGCTTGCCGAGCAGCGG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFRQQIDQARQALGGQFDIKMFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMSDPMIASLKKPDGSIDVERYAQLLSFQGMTPEQYQERVRYS
LSLQQIPASIVSSAFTPKSLAQRLSELAAQQREVQALVLKTSDFAAKVQPTDAQLAAYYDAHKQSFATPETATIQYLVYS
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKTAAKTKAEQLLADVKAHPDQFAQVAQKSSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGDVSGVVQSDLGFHILKATEVKPAAVKPFADVKDQIAAELKQQYAS
KAFTDNAEGFTSTVYEKAKTLQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDSVKSQNNTQAIDIGNN
TLISARVTDYKPAAVPALDAIKDVVRQKVVAEQAAELAKKDGVAKLAELQKSKSADGFAAAQKVSRTQSQGLTPAALSAV
YKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTAGQSQ
DGDN

Sequences:

>Translated_644_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFRQQIDQARQALGGQFDIKMFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMSDPMIASLKKPDGSIDVERYAQLLSFQGMTPEQYQERVRYS
LSLQQIPASIVSSAFTPKSLAQRLSELAAQQREVQALVLKTSDFAAKVQPTDAQLAAYYDAHKQSFATPETATIQYLVYS
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKTAAKTKAEQLLADVKAHPDQFAQVAQKSSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGDVSGVVQSDLGFHILKATEVKPAAVKPFADVKDQIAAELKQQYAS
KAFTDNAEGFTSTVYEKAKTLQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDSVKSQNNTQAIDIGNN
TLISARVTDYKPAAVPALDAIKDVVRQKVVAEQAAELAKKDGVAKLAELQKSKSADGFAAAQKVSRTQSQGLTPAALSAV
YKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTAGQSQ
DGDN
>Mature_644_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFRQQIDQARQALGGQFDIKMFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMSDPMIASLKKPDGSIDVERYAQLLSFQGMTPEQYQERVRYS
LSLQQIPASIVSSAFTPKSLAQRLSELAAQQREVQALVLKTSDFAAKVQPTDAQLAAYYDAHKQSFATPETATIQYLVYS
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKTAAKTKAEQLLADVKAHPDQFAQVAQKSSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGDVSGVVQSDLGFHILKATEVKPAAVKPFADVKDQIAAELKQQYAS
KAFTDNAEGFTSTVYEKAKTLQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDSVKSQNNTQAIDIGNN
TLISARVTDYKPAAVPALDAIKDVVRQKVVAEQAAELAKKDGVAKLAELQKSKSADGFAAAQKVSRTQSQGLTPAALSAV
YKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTAGQSQ
DGDN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=647, Percent_Identity=27.3570324574961, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69027; Mature: 69027

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCHHH
QQIDQARQALGGQFDIKMFDTPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMS
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHC
DPMIASLKKPDGSIDVERYAQLLSFQGMTPEQYQERVRYSLSLQQIPASIVSSAFTPKSL
CCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AQRLSELAAQQREVQALVLKTSDFAAKVQPTDAQLAAYYDAHKQSFATPETATIQYLVYS
HHHHHHHHHHHHHHHEEEEECCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEC
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKTAAKTKAEQL
CHHHHCCCCCCCHHHHHHCCCCCCEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHH
LADVKAHPDQFAQVAQKSSQDAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGDVSGV
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHH
VQSDLGFHILKATEVKPAAVKPFADVKDQIAAELKQQYASKAFTDNAEGFTSTVYEKAKT
HHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDSVKSQNNTQAIDIGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCC
TLISARVTDYKPAAVPALDAIKDVVRQKVVAEQAAELAKKDGVAKLAELQKSKSADGFAA
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
AQKVSRTQSQGLTPAALSAVYKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQL
HHHHHHHHHCCCCHHHHHHHHHHCCHHCCCEEEEEECCCCEEEEEEEEECCCCCCCHHHH
AAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTAGQSQDGDN
HHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDDSANVAAVNGHKITRVEFDGAFR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCEEEEEEECCHHH
QQIDQARQALGGQFDIKMFDTPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVRDALMS
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHC
DPMIASLKKPDGSIDVERYAQLLSFQGMTPEQYQERVRYSLSLQQIPASIVSSAFTPKSL
CCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AQRLSELAAQQREVQALVLKTSDFAAKVQPTDAQLAAYYDAHKQSFATPETATIQYLVYS
HHHHHHHHHHHHHHHEEEEECCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEC
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAPGSASAADKTAAKTKAEQL
CHHHHCCCCCCCHHHHHHCCCCCCEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHH
LADVKAHPDQFAQVAQKSSQDAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGDVSGV
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHH
VQSDLGFHILKATEVKPAAVKPFADVKDQIAAELKQQYASKAFTDNAEGFTSTVYEKAKT
HHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LQPAADKYKLTIQTATVTPTPNPQLPPTSPLNNPKFLAAVFANDSVKSQNNTQAIDIGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCC
TLISARVTDYKPAAVPALDAIKDVVRQKVVAEQAAELAKKDGVAKLAELQKSKSADGFAA
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
AQKVSRTQSQGLTPAALSAVYKVDAKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQL
HHHHHHHHHCCCCHHHHHHHHHHCCHHCCCEEEEEECCCCEEEEEEEEECCCCCCCHHHH
AAAQQQMAQVDAQSEGEAYLAALRDRSKVKLYGSTAGQSQDGDN
HHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]