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The map label for this gene is zraR [H]

Identifier: 78066511

GI number: 78066511

Start: 2078751

End: 2080133

Strand: Reverse

Name: zraR [H]

Synonym: Bcep18194_A5042

Alternate gene names: 78066511

Gene position: 2080133-2078751 (Counterclockwise)

Preceding gene: 78066516

Following gene: 78066510

Centisome position: 56.31

GC content: 69.56

Gene sequence:

>1383_bases
ATGAATCCGCACGACACCATCCCGATCGTCCCCGCGCCGCGCCACGACGTCATGCCCGACGTACGCGCGCTCGTCGCGTA
TCTCGAGCAGGATCCGCAGCCGATGATCGTCGTCGATCCCGACTACCGCATCCTCGCGGCGAACGATGCGTACCGGCGCC
AGTTCGGCGTCGCGGGCGTCGAGCATGTGGGCCGGCACTGCTTCCAGGTCTCGCATCACTACGACGTGCCGTGCGATCAG
GCCGGCGAGCATTGCCCGATGAAGCAGGCGCTCGAATCGCGCGGGTTGAACCGCGTGCTGCACATCCATCACACGCCGCG
CGGCCCCGAACATGTCGACGTCGAATTGCGGCCGATCTTCGATGCACACGGCAACGTGATCGCGTATGTCGAGCGGCTGA
CGACGGTGCGCAGCGCGTCCGCGCAGCCGAGTGCGGAAGGGCTCGTCGGCGGCGCGGACGCATTCAACGCGGCGCTCGGC
GCATTGCAGCGCGTCGCGCCCTCGATGCTGCCGGTGCTGCTGCTCGGTGAATCGGGCACCGGCAAGGAGCTGTTCGCCCG
CGCGCTGCACGAGGCGAGCGATCGCGCGATGGGGCCGTTCGTCGTCGTCGATTGCTCGGGGATCGCCGAGACGCTGTTCG
AGAGCGAACTGTTCGGTTACGAGAAGGGCGCGTTCACGGGTGCGAACCAGCGCAAGCCGGGCCTCGTCGAAACCGCACAG
GGCGGCACGCTGTTTCTCGACGAGATCGGCGACGTGCCGCTGCCGATGCAGGTGAAGCTGCTGCGGCTGATCGAGTCGGG
CACGTTCCGCCGTGTCGGCGGCGTCGAGGCGCTGCGTGCGGATTTCCGGCTGGTCGCGGCGACGCACAAGCCGCTGCGCG
AGATGATCGACGACGGCCGGTTCCGGCAGGACCTCTACTACCGGATCAATGCGTTTCCGATTCCGTTGCCGGCGCTGCGC
GACCGGCGCGGGGACGTCGCGCTGCTGGCCGAATCGATCCTGCGGCGGATCGCGAACGCGCGCGCCAGTGCGGGCGACGC
GAGCGCGCGGCCATTCGTGCTGACCGAGCGCGCACGTGCGTGTCTCGATGCGTATGCGTGGCCGGGCAACATTCGCGAGC
TGCGCAACGTGCTCGAACGCGCGTGCCTGTTCGCGGACGACGGGACGATCCGCGTCGAGCATCTGCCGGCCGAGCTGGTC
GCCGCATCGGCGGCGCCGCAGGACCGGACGGCCGATGCGCGCGGCATGTCGGACGCGGAGCTCGTGCGCATCGCGCGCAC
GTTCGACGGCACGCGCAAGGCGCTCGCCGAGCAGGTCGGGATGAGCGAGCGGACGTTGTACCGGCGGATGAAGGCGCTTG
GGCTCGGGACGCGCGAGCGCTGA

Upstream 100 bases:

>100_bases
CCTCCGTCCGTCACTGTGGACTGCCACAACTGGCAGTGTCGTGGCAGAATTGGCAGTCCGTCTGGCAGTTTGTCAGTCCG
CCCCTTCACCGAGCGTCCGC

Downstream 100 bases:

>100_bases
GCGGGCGTGCGGTGGGCGACTGGCAGCGGCAGGCGGCTTTGTCGATAATGGCGCGTTCGATCCAGATCCCACCTCCCACC
TCGCCGATGAAGACACGCTT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNPHDTIPIVPAPRHDVMPDVRALVAYLEQDPQPMIVVDPDYRILAANDAYRRQFGVAGVEHVGRHCFQVSHHYDVPCDQ
AGEHCPMKQALESRGLNRVLHIHHTPRGPEHVDVELRPIFDAHGNVIAYVERLTTVRSASAQPSAEGLVGGADAFNAALG
ALQRVAPSMLPVLLLGESGTGKELFARALHEASDRAMGPFVVVDCSGIAETLFESELFGYEKGAFTGANQRKPGLVETAQ
GGTLFLDEIGDVPLPMQVKLLRLIESGTFRRVGGVEALRADFRLVAATHKPLREMIDDGRFRQDLYYRINAFPIPLPALR
DRRGDVALLAESILRRIANARASAGDASARPFVLTERARACLDAYAWPGNIRELRNVLERACLFADDGTIRVEHLPAELV
AASAAPQDRTADARGMSDAELVRIARTFDGTRKALAEQVGMSERTLYRRMKALGLGTRER

Sequences:

>Translated_460_residues
MNPHDTIPIVPAPRHDVMPDVRALVAYLEQDPQPMIVVDPDYRILAANDAYRRQFGVAGVEHVGRHCFQVSHHYDVPCDQ
AGEHCPMKQALESRGLNRVLHIHHTPRGPEHVDVELRPIFDAHGNVIAYVERLTTVRSASAQPSAEGLVGGADAFNAALG
ALQRVAPSMLPVLLLGESGTGKELFARALHEASDRAMGPFVVVDCSGIAETLFESELFGYEKGAFTGANQRKPGLVETAQ
GGTLFLDEIGDVPLPMQVKLLRLIESGTFRRVGGVEALRADFRLVAATHKPLREMIDDGRFRQDLYYRINAFPIPLPALR
DRRGDVALLAESILRRIANARASAGDASARPFVLTERARACLDAYAWPGNIRELRNVLERACLFADDGTIRVEHLPAELV
AASAAPQDRTADARGMSDAELVRIARTFDGTRKALAEQVGMSERTLYRRMKALGLGTRER
>Mature_460_residues
MNPHDTIPIVPAPRHDVMPDVRALVAYLEQDPQPMIVVDPDYRILAANDAYRRQFGVAGVEHVGRHCFQVSHHYDVPCDQ
AGEHCPMKQALESRGLNRVLHIHHTPRGPEHVDVELRPIFDAHGNVIAYVERLTTVRSASAQPSAEGLVGGADAFNAALG
ALQRVAPSMLPVLLLGESGTGKELFARALHEASDRAMGPFVVVDCSGIAETLFESELFGYEKGAFTGANQRKPGLVETAQ
GGTLFLDEIGDVPLPMQVKLLRLIESGTFRRVGGVEALRADFRLVAATHKPLREMIDDGRFRQDLYYRINAFPIPLPALR
DRRGDVALLAESILRRIANARASAGDASARPFVLTERARACLDAYAWPGNIRELRNVLERACLFADDGTIRVEHLPAELV
AASAAPQDRTADARGMSDAELVRIARTFDGTRKALAEQVGMSERTLYRRMKALGLGTRER

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=309, Percent_Identity=43.042071197411, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788550, Length=303, Percent_Identity=40.2640264026403, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1789233, Length=337, Percent_Identity=37.9821958456973, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789087, Length=334, Percent_Identity=39.2215568862275, Blast_Score=215, Evalue=4e-57,
Organism=Escherichia coli, GI1790299, Length=363, Percent_Identity=35.8126721763085, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI87082117, Length=329, Percent_Identity=38.9057750759878, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87081872, Length=239, Percent_Identity=46.0251046025105, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786524, Length=301, Percent_Identity=41.1960132890365, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1788905, Length=228, Percent_Identity=43.859649122807, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI87082152, Length=308, Percent_Identity=40.5844155844156, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1787583, Length=451, Percent_Identity=31.4855875831486, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1789828, Length=307, Percent_Identity=36.4820846905537, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081858, Length=298, Percent_Identity=31.5436241610738, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50503; Mature: 50503

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPHDTIPIVPAPRHDVMPDVRALVAYLEQDPQPMIVVDPDYRILAANDAYRRQFGVAGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHHHHHCCCCH
EHVGRHCFQVSHHYDVPCDQAGEHCPMKQALESRGLNRVLHIHHTPRGPEHVDVELRPIF
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEEE
DAHGNVIAYVERLTTVRSASAQPSAEGLVGGADAFNAALGALQRVAPSMLPVLLLGESGT
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCC
GKELFARALHEASDRAMGPFVVVDCSGIAETLFESELFGYEKGAFTGANQRKPGLVETAQ
CHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECC
GGTLFLDEIGDVPLPMQVKLLRLIESGTFRRVGGVEALRADFRLVAATHKPLREMIDDGR
CCEEEECCCCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
FRQDLYYRINAFPIPLPALRDRRGDVALLAESILRRIANARASAGDASARPFVLTERARA
HHHHHHEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHH
CLDAYAWPGNIRELRNVLERACLFADDGTIRVEHLPAELVAASAAPQDRTADARGMSDAE
HHHHHCCCCCHHHHHHHHHHHHEECCCCEEEEEECCHHHHHHCCCCCCCCCCCCCCCHHH
LVRIARTFDGTRKALAEQVGMSERTLYRRMKALGLGTRER
HHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPHDTIPIVPAPRHDVMPDVRALVAYLEQDPQPMIVVDPDYRILAANDAYRRQFGVAGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHHHHHCCCCH
EHVGRHCFQVSHHYDVPCDQAGEHCPMKQALESRGLNRVLHIHHTPRGPEHVDVELRPIF
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEEE
DAHGNVIAYVERLTTVRSASAQPSAEGLVGGADAFNAALGALQRVAPSMLPVLLLGESGT
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCC
GKELFARALHEASDRAMGPFVVVDCSGIAETLFESELFGYEKGAFTGANQRKPGLVETAQ
CHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECC
GGTLFLDEIGDVPLPMQVKLLRLIESGTFRRVGGVEALRADFRLVAATHKPLREMIDDGR
CCEEEECCCCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
FRQDLYYRINAFPIPLPALRDRRGDVALLAESILRRIANARASAGDASARPFVLTERARA
HHHHHHEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHH
CLDAYAWPGNIRELRNVLERACLFADDGTIRVEHLPAELVAASAAPQDRTADARGMSDAE
HHHHHCCCCCHHHHHHHHHHHHEECCCCEEEEEECCHHHHHHCCCCCCCCCCCCCCCHHH
LVRIARTFDGTRKALAEQVGMSERTLYRRMKALGLGTRER
HHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]