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The map label for this gene is betA [H]

Identifier: 78065840

GI number: 78065840

Start: 1323038

End: 1324708

Strand: Reverse

Name: betA [H]

Synonym: Bcep18194_A4369

Alternate gene names: 78065840

Gene position: 1324708-1323038 (Counterclockwise)

Preceding gene: 78065845

Following gene: 78065839

Centisome position: 35.86

GC content: 68.52

Gene sequence:

>1671_bases
ATGAAAACCGATTCGTACGACTACGTGATCGTCGGCGCCGGCTCGGCCGGTTGCGCACTCGCCTACCGGCTCGGCGAGGA
TCCGAACGTCCGCATCCTCGTGATCGAGGCCGGCGAACAGGATCGCTCGCCGTACATCAAGGTGCCGCTGACGTGGGGCC
AGATTCTGAAGAACCGGCTGTTCGACTGGGGCTATTTCACCGAGCCGGAAGCCGGCATGGACGGTCGCCGGATCGAGTGC
GCGCGCGGCAAGGTGGTGGGCGGCTCGTCGTCGATCAACGGCATGGCCTACGCACGCGGCGCGCGGGAAGACTACGAAGG
CTGGGCCGACGAGTTCGGCCTGACCGACTGGTCCTACGACGCGGTGCTGCCGTACTTCAAGCGCTCCGAATCGTGGGAGC
GCGGCGAATCGGCGTTGCGCGGCGGTCGCGGCCCGCTGACCGTGATCAAGCTCGACTATCGCGACCCGCTGGTCGGCGGC
TTTCTCGACGCGACGCGTGCGTGCGGCTATCCGGAAAACGACGACTACAACGGCGCATCCGTCGAAGGCTTCGGGCCGAT
GCAGGCCACCATCCGCAACGGCCTGCGCTGCAGCGCCGCGGTCGCCTATCTGCGCCCGGCGCTCGCGCGCGGCAACGTCA
CGCTGGTGACCGGGGCCCTCGCGAAACGGATCGTGCTCGATACCGACAGCGGTACGCCGCGCGCCATCGCGATCGAGTAT
CGCCGTGGCGAGTCCGACTACCGCGCCGATGCACGCCGCGAAGTCATCCTCTGCGGCGGCGTGATCAATTCGCCGCAGCT
GCTGATGCTCTCCGGCATCGGCGCGGCCGACAGCCTGCGCACGCACGGCATCGCGTCGAAAGTCGAATTGCCCGGCGTGG
GCGCCAACCTGCATGACCACATCGTGTTCGACCTGCGCTGGAGCCGCAAGGAACCGGGGCCGCTGCACCGGATGATGCGT
GCCGACCGTATCGCGTTCGACGTCGCGCGCACGCTGGCAGGCGGCAACGGCTTCTCGAGTGCGATCCCCGCCGCCGCGCT
CGGGCTGGTCCGCAGCCAGCCTCACCTGCCGCTGCCGGACGTGCAGCTGATCCTCGCGGCCGGCGCGATGAACGCCGCGC
CGTACTTCGAGCCGTTCAAGCACGCGTATGCCGATTCGTTCGCGATCAAGGGCATTTTCCTCACGCCCGAAAGCCGCGGC
CGCGTGTCGCTGAAGTCGGCCGATCCGGCCCAGCACGCGCGGATCGAGCAAAACTTCCTCGCCACCGAGCACGATCGCGT
CGCAGCGCGCGAGATGTTCCGGCGCATGCGGGAAATCGGCGCGCAGGCCGGGCTGCGCCCGTTCATCGACGCAGAGATCG
CACCGGGCCCGCAGGTCCAGAGCGACGCAGACGTCGACGCCTTCATTCGTCGTGTCGCGATCACCCTTCATCACCCGGTC
GGCACGTGCCGCATGGGTCGCGACGACGATCCGGCGGCCGTGGTCGATACGCAGATGCGCGTGCGCGGCGTCGCCGGATT
GCGGGTGGTCGACGGCTCGTCGATCCCGCGCATCATCCGCGGGCCGACCAACGCGCTGATCATGACGATGGCCGAACGCG
CAGCCGATTTCATGACCGGGAAAGCCATGCCCGTGCCGCAGGCGCAGGTTCGCGCCACCGCACCGATGTAG

Upstream 100 bases:

>100_bases
ACATCATGGTTCGTTCGACGCCTGTTCCGGCCGGTCGCCGCGCCCCGCGTTCGCGGGTTGCGCCGGCCTGCCCTGCTGCC
CGGCACCGCGAGGTGCGGCA

Downstream 100 bases:

>100_bases
ACCGTCGTGCGCGGGGCAGCACACCACGCCCCGCTTCGATTCATTCCAATTCATTCAGGAGACACCGATGACCCATTCCT
GCGGGCATGCGCACTGCCAT

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MKTDSYDYVIVGAGSAGCALAYRLGEDPNVRILVIEAGEQDRSPYIKVPLTWGQILKNRLFDWGYFTEPEAGMDGRRIEC
ARGKVVGGSSSINGMAYARGAREDYEGWADEFGLTDWSYDAVLPYFKRSESWERGESALRGGRGPLTVIKLDYRDPLVGG
FLDATRACGYPENDDYNGASVEGFGPMQATIRNGLRCSAAVAYLRPALARGNVTLVTGALAKRIVLDTDSGTPRAIAIEY
RRGESDYRADARREVILCGGVINSPQLLMLSGIGAADSLRTHGIASKVELPGVGANLHDHIVFDLRWSRKEPGPLHRMMR
ADRIAFDVARTLAGGNGFSSAIPAAALGLVRSQPHLPLPDVQLILAAGAMNAAPYFEPFKHAYADSFAIKGIFLTPESRG
RVSLKSADPAQHARIEQNFLATEHDRVAAREMFRRMREIGAQAGLRPFIDAEIAPGPQVQSDADVDAFIRRVAITLHHPV
GTCRMGRDDDPAAVVDTQMRVRGVAGLRVVDGSSIPRIIRGPTNALIMTMAERAADFMTGKAMPVPQAQVRATAPM

Sequences:

>Translated_556_residues
MKTDSYDYVIVGAGSAGCALAYRLGEDPNVRILVIEAGEQDRSPYIKVPLTWGQILKNRLFDWGYFTEPEAGMDGRRIEC
ARGKVVGGSSSINGMAYARGAREDYEGWADEFGLTDWSYDAVLPYFKRSESWERGESALRGGRGPLTVIKLDYRDPLVGG
FLDATRACGYPENDDYNGASVEGFGPMQATIRNGLRCSAAVAYLRPALARGNVTLVTGALAKRIVLDTDSGTPRAIAIEY
RRGESDYRADARREVILCGGVINSPQLLMLSGIGAADSLRTHGIASKVELPGVGANLHDHIVFDLRWSRKEPGPLHRMMR
ADRIAFDVARTLAGGNGFSSAIPAAALGLVRSQPHLPLPDVQLILAAGAMNAAPYFEPFKHAYADSFAIKGIFLTPESRG
RVSLKSADPAQHARIEQNFLATEHDRVAAREMFRRMREIGAQAGLRPFIDAEIAPGPQVQSDADVDAFIRRVAITLHHPV
GTCRMGRDDDPAAVVDTQMRVRGVAGLRVVDGSSIPRIIRGPTNALIMTMAERAADFMTGKAMPVPQAQVRATAPM
>Mature_556_residues
MKTDSYDYVIVGAGSAGCALAYRLGEDPNVRILVIEAGEQDRSPYIKVPLTWGQILKNRLFDWGYFTEPEAGMDGRRIEC
ARGKVVGGSSSINGMAYARGAREDYEGWADEFGLTDWSYDAVLPYFKRSESWERGESALRGGRGPLTVIKLDYRDPLVGG
FLDATRACGYPENDDYNGASVEGFGPMQATIRNGLRCSAAVAYLRPALARGNVTLVTGALAKRIVLDTDSGTPRAIAIEY
RRGESDYRADARREVILCGGVINSPQLLMLSGIGAADSLRTHGIASKVELPGVGANLHDHIVFDLRWSRKEPGPLHRMMR
ADRIAFDVARTLAGGNGFSSAIPAAALGLVRSQPHLPLPDVQLILAAGAMNAAPYFEPFKHAYADSFAIKGIFLTPESRG
RVSLKSADPAQHARIEQNFLATEHDRVAAREMFRRMREIGAQAGLRPFIDAEIAPGPQVQSDADVDAFIRRVAITLHHPV
GTCRMGRDDDPAAVVDTQMRVRGVAGLRVVDGSSIPRIIRGPTNALIMTMAERAADFMTGKAMPVPQAQVRATAPM

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=564, Percent_Identity=41.8439716312057, Blast_Score=389, Evalue=1e-108,
Organism=Escherichia coli, GI1786503, Length=555, Percent_Identity=40.3603603603604, Blast_Score=364, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17532301, Length=568, Percent_Identity=35.7394366197183, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI24642055, Length=577, Percent_Identity=37.261698440208, Blast_Score=323, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24650267, Length=575, Percent_Identity=37.2173913043478, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI24642042, Length=592, Percent_Identity=35.304054054054, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI45549471, Length=574, Percent_Identity=34.8432055749129, Blast_Score=281, Evalue=8e-76,
Organism=Drosophila melanogaster, GI45551458, Length=575, Percent_Identity=34.7826086956522, Blast_Score=281, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24642059, Length=574, Percent_Identity=34.3205574912892, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI24642035, Length=575, Percent_Identity=35.1304347826087, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24642039, Length=565, Percent_Identity=33.6283185840708, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24642048, Length=576, Percent_Identity=32.8125, Blast_Score=266, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24642037, Length=573, Percent_Identity=34.9040139616056, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI17137792, Length=551, Percent_Identity=32.8493647912886, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI18859995, Length=566, Percent_Identity=34.2756183745583, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI24642051, Length=575, Percent_Identity=31.6521739130435, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI18859993, Length=569, Percent_Identity=30.0527240773286, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24645930, Length=582, Percent_Identity=30.0687285223368, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24642057, Length=593, Percent_Identity=28.4991568296796, Blast_Score=139, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 60325; Mature: 60325

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00623 GMC_OXRED_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDSYDYVIVGAGSAGCALAYRLGEDPNVRILVIEAGEQDRSPYIKVPLTWGQILKNRL
CCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCEEEEECCHHHHHHHHC
FDWGYFTEPEAGMDGRRIECARGKVVGGSSSINGMAYARGAREDYEGWADEFGLTDWSYD
CCCCCCCCCCCCCCCCEEEECCCEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCHH
AVLPYFKRSESWERGESALRGGRGPLTVIKLDYRDPLVGGFLDATRACGYPENDDYNGAS
HHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCC
VEGFGPMQATIRNGLRCSAAVAYLRPALARGNVTLVTGALAKRIVLDTDSGTPRAIAIEY
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEHHHHCEEEEECCCCCCEEEEEEE
RRGESDYRADARREVILCGGVINSPQLLMLSGIGAADSLRTHGIASKVELPGVGANLHDH
ECCCCHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHCCCCCEEECCCCCCCCCCE
IVFDLRWSRKEPGPLHRMMRADRIAFDVARTLAGGNGFSSAIPAAALGLVRSQPHLPLPD
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
VQLILAAGAMNAAPYFEPFKHAYADSFAIKGIFLTPESRGRVSLKSADPAQHARIEQNFL
HHHHEECCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
ATEHDRVAAREMFRRMREIGAQAGLRPFIDAEIAPGPQVQSDADVDAFIRRVAITLHHPV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCC
GTCRMGRDDDPAAVVDTQMRVRGVAGLRVVDGSSIPRIIRGPTNALIMTMAERAADFMTG
CCCCCCCCCCCCEEEECHHHEECCCCEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHCC
KAMPVPQAQVRATAPM
CCCCCCHHHCEECCCC
>Mature Secondary Structure
MKTDSYDYVIVGAGSAGCALAYRLGEDPNVRILVIEAGEQDRSPYIKVPLTWGQILKNRL
CCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCEEEEECCHHHHHHHHC
FDWGYFTEPEAGMDGRRIECARGKVVGGSSSINGMAYARGAREDYEGWADEFGLTDWSYD
CCCCCCCCCCCCCCCCEEEECCCEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCHH
AVLPYFKRSESWERGESALRGGRGPLTVIKLDYRDPLVGGFLDATRACGYPENDDYNGAS
HHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCC
VEGFGPMQATIRNGLRCSAAVAYLRPALARGNVTLVTGALAKRIVLDTDSGTPRAIAIEY
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEHHHHCEEEEECCCCCCEEEEEEE
RRGESDYRADARREVILCGGVINSPQLLMLSGIGAADSLRTHGIASKVELPGVGANLHDH
ECCCCHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHCCCCCEEECCCCCCCCCCE
IVFDLRWSRKEPGPLHRMMRADRIAFDVARTLAGGNGFSSAIPAAALGLVRSQPHLPLPD
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
VQLILAAGAMNAAPYFEPFKHAYADSFAIKGIFLTPESRGRVSLKSADPAQHARIEQNFL
HHHHEECCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
ATEHDRVAAREMFRRMREIGAQAGLRPFIDAEIAPGPQVQSDADVDAFIRRVAITLHHPV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCC
GTCRMGRDDDPAAVVDTQMRVRGVAGLRVVDGSSIPRIIRGPTNALIMTMAERAADFMTG
CCCCCCCCCCCCEEEECHHHEECCCCEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHCC
KAMPVPQAQVRATAPM
CCCCCCHHHCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]