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The map label for this gene is mdtA [H]

Identifier: 78065778

GI number: 78065778

Start: 1251667

End: 1253037

Strand: Reverse

Name: mdtA [H]

Synonym: Bcep18194_A4306

Alternate gene names: 78065778

Gene position: 1253037-1251667 (Counterclockwise)

Preceding gene: 78065779

Following gene: 78065777

Centisome position: 33.92

GC content: 68.13

Gene sequence:

>1371_bases
ATGGATAACGAACAAAAGCCCACGCCTCCTTCGAAAGACCCCGCGTCTCCCGCCGCGCGGCGCCCGCGCCGCACGCTGAT
GGCCGGCGCGCTCGCGGTCGTCGTCATCGGCGGCCTGCTGTGGTGGCATCCGTGGAACCGCACGCCGGCAACCGGCACTG
CGGCGAGCGGCGCGGGCGCAAGCGCGGCCGGCGGTACCGGCGGCCACCGCGGCCGTGGCGGCCCCGCCGCGATGGCGAAC
ATTCCGCAGCCCGTTCAGGTCGCGACCGCGACGCAGGGCGAAATGCCGATCGTGCTGTCCGCGCTCGGCACCGTCACGCC
GCTCGCGAACGTAACGGTCAAGACGCAGTTGTCCGGCTACCTGCAGTCGGTAGCGTTCCAGGAAGGCCAGATCGTCAAGA
AGGGCGACGTGCTCGCGCAGATCGACCCGCGCCCGTACCAGGTGTCGCTCGAGAATGCCGAAGGCACGCACGCGCGCGAC
TCGGCACTGCTCACAACGGCCCGCCTCGACCTGAAGCGCTACCAGACGCTGCTGTCGCAGGATTCGATCGCGTCGCAGAC
CGTCGATACCCAAGCGTCGCTCGTCAAGCAATACGAAGGCGCGGTGAAGACCGACCAGGCCGCGATCGATTCCGCGAAGC
TGAACCTCACGTATGCGCGCATCACCGCGCCGGTGTCGGGCCGCGTCGGCCTGCGCCAGGTCGACCCCGGCAACTACGTG
ACGCCGGGCGATACCAACGGCCTCGTCGTGATCACGCAGCTGCAGCCGATGAGCGTGATCTTCACGACGTCGGAAGACAA
CCTGCCGCAGATCCTCAAGCAGGTGAACGCAGGCCAGAAACTGTCGGTCACCGCATACAACCGCAACAACACGGTGCCGC
TCGAAACCGGCTCGCTCGCGACGCTCGACAACCAGATCGACACGAGCACGGGTACGGTCAAGCTGCGTGCAAACTTCGAT
AACAAGGAAGGCATGCTGTTCCCGAATCAGTTCGTGAACACGCGCCTGCTCGTCGACGTACTGCGCAACGCGACGATCGT
GCCGACGGCGGCCGTGCTGACCGGCTCGATCGGCCAGTTCGTCTATGTCGTGAAACCCGACAACACGGTGACGGTGCGCA
AGGTCACGATCGGCCCGGTCGACGGCGAACGCACGAGCATCGTCAGCGGCGTGTCGCTCGGCGAGCGCGTGGTGACCGAC
GGCTCCGACCGCTTGCGCGAAGGCGCGAAGATCTCGATCCCGGCCGACAAGCCGAAAGGCGCGTCGGGCGCGCACGGCGC
CGCTGCGGCGTCGGGGGCATCGGGTGCCGGCGGCCATCGCGGCGGACACAAGCACGGCGCGTCGCAGGCAGCGGCCTCCG
CGGCCCAGTAA

Upstream 100 bases:

>100_bases
GCCCGGACCGAGCCGGACGCCCCCTCCCGGCACCGCTCGCCCACGCGCAGCCCAGCAGTCCGATTTCCGGCACGCCGCGC
CGTCTTCCTGACAGATCACG

Downstream 100 bases:

>100_bases
CGCGCGGGCCGCTCGATGAATCCATCCCGCCTATTCATTCTCCGGCCGGTCGGCACCGCCCTCCTGATGGCGGCGATCAT
GCTGGCCGGTCTCGTCGCGC

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MDNEQKPTPPSKDPASPAARRPRRTLMAGALAVVVIGGLLWWHPWNRTPATGTAASGAGASAAGGTGGHRGRGGPAAMAN
IPQPVQVATATQGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVAFQEGQIVKKGDVLAQIDPRPYQVSLENAEGTHARD
SALLTTARLDLKRYQTLLSQDSIASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYV
TPGDTNGLVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLATLDNQIDTSTGTVKLRANFD
NKEGMLFPNQFVNTRLLVDVLRNATIVPTAAVLTGSIGQFVYVVKPDNTVTVRKVTIGPVDGERTSIVSGVSLGERVVTD
GSDRLREGAKISIPADKPKGASGAHGAAAASGASGAGGHRGGHKHGASQAAASAAQ

Sequences:

>Translated_456_residues
MDNEQKPTPPSKDPASPAARRPRRTLMAGALAVVVIGGLLWWHPWNRTPATGTAASGAGASAAGGTGGHRGRGGPAAMAN
IPQPVQVATATQGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVAFQEGQIVKKGDVLAQIDPRPYQVSLENAEGTHARD
SALLTTARLDLKRYQTLLSQDSIASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYV
TPGDTNGLVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLATLDNQIDTSTGTVKLRANFD
NKEGMLFPNQFVNTRLLVDVLRNATIVPTAAVLTGSIGQFVYVVKPDNTVTVRKVTIGPVDGERTSIVSGVSLGERVVTD
GSDRLREGAKISIPADKPKGASGAHGAAAASGASGAGGHRGGHKHGASQAAASAAQ
>Mature_456_residues
MDNEQKPTPPSKDPASPAARRPRRTLMAGALAVVVIGGLLWWHPWNRTPATGTAASGAGASAAGGTGGHRGRGGPAAMAN
IPQPVQVATATQGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVAFQEGQIVKKGDVLAQIDPRPYQVSLENAEGTHARD
SALLTTARLDLKRYQTLLSQDSIASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYV
TPGDTNGLVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLATLDNQIDTSTGTVKLRANFD
NKEGMLFPNQFVNTRLLVDVLRNATIVPTAAVLTGSIGQFVYVVKPDNTVTVRKVTIGPVDGERTSIVSGVSLGERVVTD
GSDRLREGAKISIPADKPKGASGAHGAAAASGASGAGGHRGGHKHGASQAAASAAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=376, Percent_Identity=46.2765957446808, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI1789929, Length=321, Percent_Identity=30.5295950155763, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1789665, Length=377, Percent_Identity=31.0344827586207, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786668, Length=360, Percent_Identity=31.1111111111111, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081796, Length=350, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081951, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47307; Mature: 47307

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNEQKPTPPSKDPASPAARRPRRTLMAGALAVVVIGGLLWWHPWNRTPATGTAASGAGA
CCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
SAAGGTGGHRGRGGPAAMANIPQPVQVATATQGEMPIVLSALGTVTPLANVTVKTQLSGY
CCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCEEEEHHHHHH
LQSVAFQEGQIVKKGDVLAQIDPRPYQVSLENAEGTHARDSALLTTARLDLKRYQTLLSQ
HHHHHHCCCCEEECCCEEEEECCCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHC
DSIASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYV
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEEEEEEECCCCCCCCCEEECCCCEE
TPGDTNGLVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLA
CCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCCEE
TLDNQIDTSTGTVKLRANFDNKEGMLFPNQFVNTRLLVDVLRNATIVPTAAVLTGSIGQF
EECCCCCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHCCEECCCHHHHHCCCCCE
VYVVKPDNTVTVRKVTIGPVDGERTSIVSGVSLGERVVTDGSDRLREGAKISIPADKPKG
EEEECCCCEEEEEEEEECCCCCCHHHEEECCCCCCCEECCCHHHHHCCCEEEECCCCCCC
ASGAHGAAAASGASGAGGHRGGHKHGASQAAASAAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MDNEQKPTPPSKDPASPAARRPRRTLMAGALAVVVIGGLLWWHPWNRTPATGTAASGAGA
CCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
SAAGGTGGHRGRGGPAAMANIPQPVQVATATQGEMPIVLSALGTVTPLANVTVKTQLSGY
CCCCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCEEEEHHHHHH
LQSVAFQEGQIVKKGDVLAQIDPRPYQVSLENAEGTHARDSALLTTARLDLKRYQTLLSQ
HHHHHHCCCCEEECCCEEEEECCCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHC
DSIASQTVDTQASLVKQYEGAVKTDQAAIDSAKLNLTYARITAPVSGRVGLRQVDPGNYV
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEEEEEEECCCCCCCCCEEECCCCEE
TPGDTNGLVVITQLQPMSVIFTTSEDNLPQILKQVNAGQKLSVTAYNRNNTVPLETGSLA
CCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCCEE
TLDNQIDTSTGTVKLRANFDNKEGMLFPNQFVNTRLLVDVLRNATIVPTAAVLTGSIGQF
EECCCCCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHCCEECCCHHHHHCCCCCE
VYVVKPDNTVTVRKVTIGPVDGERTSIVSGVSLGERVVTDGSDRLREGAKISIPADKPKG
EEEECCCCEEEEEEEEECCCCCCHHHEEECCCCCCCEECCCHHHHHCCCEEEECCCCCCC
ASGAHGAAAASGASGAGGHRGGHKHGASQAAASAAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA