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The map label for this gene is pncB [H]

Identifier: 78065685

GI number: 78065685

Start: 1147346

End: 1148545

Strand: Direct

Name: pncB [H]

Synonym: Bcep18194_A4213

Alternate gene names: 78065685

Gene position: 1147346-1148545 (Clockwise)

Preceding gene: 78065678

Following gene: 78065686

Centisome position: 31.06

GC content: 62.42

Gene sequence:

>1200_bases
ATGATCATCACTTCGCTGCTCGACACGGATCTCTACAAGTTCACGATGATGCAGGTCGTCCTGCATCACTTCCCCGCTGC
AAGCGTCGAATACCGTTTCCGCTGCCGCACGCCCGGCGTCGATCTCGTGCCGTACATCGACGAGATCCGCGACGAGGTGC
GCGGCCTGTGCGCGCTGCGTTTTTCCGACGTCGAACTCGACTACCTGCGGCGGATGCGCTTCATCAAAAGCGATTTCGTC
GATTTCCTCGCGCTGTTCCACCTGAACGAGAAGTACATCTCGATCACGCCGTCGCCGAAGGGCAACGGCGAAATCGACAT
CGAGATCATCGGGCCGTGGCTGCACACGATCCTGTTCGAGATCCCGGTGCTCGCGATCGTCAACGAAGTGTATTTCCGCA
ACACGCAGCGCGAGCCCGACTATCGCGAAGGCCGCGAACGGCTGTGCGAGAAAATCAAGCTGCTCGGTGCGAAGCCCGAG
TTCGCCGACTGCAAGATCGCCGACTACGGCACGCGCCGGCGCTTCTCGAAGGTCTGGCACGAGGAAGTCGCGCTCACCCT
GCGCGACGGCCTCGGCCCGCAGTTCGCGGGCACGAGCAACGTGCTTTATGCGATGAAGCACGGCATCACGCCGCTCGGCA
CGATGGCGCACGAGTACCTGCAGGCGTGCCAGGCGCTCGGCCCGCGGCTGCGCGATTCGCAGATCTACGGCTTCGAGATG
TGGGCGAAGGAATACCGCGGCGACCTCGGGATCGCGCTATCGGACGTCTACGGGATGGATGCATTCCTGAACGACTTCGA
CATGTACTTCTGCAAGCTGTTCGACGGCGCGCGCCACGATTCGGGCGATCCGTTCGAATGGGGCGAGCGGATGCTGCGCC
ATTACGAGTCGAACCGTTGCGACCCGCGGACCAAGGTGCTCGTGTTCTCGGACGCGCTCGACATCCCGAAGGTCATGCAG
TTGTACGAACGGTTCCGCGGCCGCTGCAAGCTCGCGTTCGGTGTCGGCACGAACCTCACCAACGATCTCGGCTACGTGCC
GCTGCAGATCGTGATCAAGATGGTCCGCTGCAACGGCCAGCCGGTCGCGAAACTGTCGGATTCGCCGGGCAAGAGCATGT
GCGACGACAAGGCGTATCTCGCATACCTGCGCCAGGTGTTCGGCATCGCGCAGCCGGTCGAGGAAGACGCGTCGAAGTAA

Upstream 100 bases:

>100_bases
TTTCACGATGGTCGGGCCCGCATTCGGGTAACATGGCCGACAGACCGGGCGGCGCGCGGTGCGCCGGGGCCCTGTCACGA
TATTGGCGGTGCCGTAAATC

Downstream 100 bases:

>100_bases
GCGTCGGCCGAACGGCCAAAACTGCGTGGCGGCGAGGTCGGCCGGTATAATCCGACGTATCGCCCGCCAACGTCACGAGG
ACCGTTCATGGACACTTCCG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFRCRTPGVDLVPYIDEIRDEVRGLCALRFSDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIEIIGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLCEKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVLYAMKHGITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYESNRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEEDASK

Sequences:

>Translated_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFRCRTPGVDLVPYIDEIRDEVRGLCALRFSDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIEIIGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLCEKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVLYAMKHGITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYESNRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEEDASK
>Mature_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFRCRTPGVDLVPYIDEIRDEVRGLCALRFSDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIEIIGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLCEKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVLYAMKHGITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYESNRCDPRTKVLVFSDALDIPKVMQ
LYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEEDASK

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=393, Percent_Identity=43.5114503816794, Blast_Score=325, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6324783, Length=401, Percent_Identity=29.6758104738155, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45908; Mature: 45908

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFRCRTPGVDLVPYIDEIRDEVRGLCALR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHE
FSDVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIEIIGPWLHTILFE
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECHHHHHHHHH
IPVLAIVNEVYFRNTQREPDYREGRERLCEKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGPQFAGTSNVLYAMKHGITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYESNRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVMQLYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEEDASK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAASVEYRFRCRTPGVDLVPYIDEIRDEVRGLCALR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHE
FSDVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIEIIGPWLHTILFE
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECHHHHHHHHH
IPVLAIVNEVYFRNTQREPDYREGRERLCEKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGPQFAGTSNVLYAMKHGITPLGTMAHEYLQACQALGPRLRDSQIYGFEM
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYESNRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVMQLYERFRGRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDKAYLAYLRQVFGIAQPVEEDASK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA