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The map label for this gene is atoC [H]

Identifier: 78065670

GI number: 78065670

Start: 1131584

End: 1132981

Strand: Direct

Name: atoC [H]

Synonym: Bcep18194_A4198

Alternate gene names: 78065670

Gene position: 1131584-1132981 (Clockwise)

Preceding gene: 78065667

Following gene: 78065671

Centisome position: 30.63

GC content: 66.17

Gene sequence:

>1398_bases
ATGGGAGCCGATCAGCGGCACGTGATCTACTATTCGCGCGAACCGAACGACGCGTTGCGCGGCCATTTCGACGAGTGCGG
TTGGCGTGTCGATCTCGCGGAGACCGTGCGAGACGTACGGCGCGTCGTACAGCATGGCGTCGCAACTGCCGGGCTGCTCG
ATTTTTCGCCGGGCTTCAAGCCCTCGGACCTGCGCGAACTCGAAACCTGTCTGAGCATTCAGCACATCGGCTGGATCGCG
GCGACGCGCCGCGGCCAGTTGCAGGACGCTACGCTGCGCCATCTCATTCGCGACTACTGTTTCGACTACGTGACGATGCC
GTACGAGACGTCGCGGATCGTCGAGACCGTCGGTCATGCACACGGGATGGTCGCGCTGACCGAACCCGTTGCACCGCCTG
TCGGCGCCGGACGCAGCGAAGGCGAAATGGTCGGAACCTGCGATGCGATGCTCGGGCTCTTCAGGACGATTCGTCGCGTC
GCGGCAACCGACGCGCCGGTGTTCATCTCCGGCGAATCGGGTACGGGCAAGGAACTGACGGCGGTTGCGATTCACGAGCG
TTCGTCGCGTGCGCAAGCGCCGTTCATCGCGATCAATTGCGGCGCGATCCCGTCGACGCTGCTGCAGGCCGAACTGTTCG
GCTATGAGCGCGGCGCATTCACCGGCGCGAACCAGCGCAAGATCGGCCGCGTCGAGGCCGCCAACGGCGGCACGCTGTTT
CTCGATGAAATCGGCGATTTGCCGCTCGAAAGCCAGGCAAGCCTGCTGCGCTTCCTGCAGGAAGGCAAGATCGAGCGGCT
GGGTGCCCATGTGTCGGTGCCGGTCGATGTGCGCGTGATCTGCGCGACCCACGTGGACATGGAAGCGGCGCTGCGCGAAG
GGCGGTTCCGCGAGGACCTGTTCCACCGCCTGTGCGTGCTGAAGATCGAGGAGCCGCCGCTGCGCGCGCGCGGCAAGGAC
ATCGAGGTGCTCGCGCGCCACATGCTCGAGCGTTTCAAGGGCGATGCGCATCGTCGCTTGCGCGGCTTTTCCCCTGACGC
GGTCGCGTCGCTGTACGGCTATTCGTGGCCGGGCAACGTGCGCGAGCTGATCAATCGCGTGCGTCGCGCGATCGTCATGT
CGGAGGGCCGGATGATCACCGCGGCCGATCTCGAGCTGAACGACTTTGCGACGCTCGCGCCCGTGTCGTTGCTGGAGGCG
CGCGAGGCGGCCGAACGGCAGGCAATCGAGCAGGCGCTGTTGCGACATCGCGGCCGTTTCGCGGATGCCGCGCGCGAACT
CGGCGTGTCGCGCGTCACGCTCTACCGGCTGATGTGCGCACACGGGATGCGCGACCGCGGCGACACGCTGGCAGGGTTTT
CGGCGCCGTTACCGGAGCTTCCGCATCACGCTTGCTAA

Upstream 100 bases:

>100_bases
TGGCGAATCGAGCCACCTTCGGCTGACCCGATTCGATCCTTTTCGCACGTGATCTGGCGTGCACGGCAATCGTTAGACGG
TTGATGAACGGGGTGAGCAT

Downstream 100 bases:

>100_bases
AATTGGCGGGTACGGCCGCCCTCGCGGCCGAAGGAACCCGCATGAAACAGTATCTCGACCTCGTTCGTACCATTCTCGAT
ACCGGCACCTGGCAGGAGAA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MGADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFKPSDLRELETCLSIQHIGWIA
ATRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHAHGMVALTEPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRV
AATDAPVFISGESGTGKELTAVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGKD
IEVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELNDFATLAPVSLLEA
REAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPLPELPHHAC

Sequences:

>Translated_465_residues
MGADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFKPSDLRELETCLSIQHIGWIA
ATRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHAHGMVALTEPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRV
AATDAPVFISGESGTGKELTAVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGKD
IEVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELNDFATLAPVSLLEA
REAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPLPELPHHAC
>Mature_464_residues
GADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFKPSDLRELETCLSIQHIGWIAA
TRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHAHGMVALTEPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRVA
ATDAPVFISGESGTGKELTAVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLFL
DEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDLFHRLCVLKIEEPPLRARGKDI
EVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELNDFATLAPVSLLEAR
EAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPLPELPHHAC

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=359, Percent_Identity=41.2256267409471, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1790437, Length=353, Percent_Identity=43.0594900849858, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1790299, Length=373, Percent_Identity=41.2868632707775, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1788905, Length=347, Percent_Identity=40.6340057636888, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=43.2515337423313, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1789233, Length=313, Percent_Identity=43.7699680511182, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=39.9350649350649, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI87082152, Length=324, Percent_Identity=43.5185185185185, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI1786524, Length=315, Percent_Identity=43.4920634920635, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=44.4444444444444, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787583, Length=316, Percent_Identity=36.0759493670886, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=34.1296928327645, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=34.9794238683128, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51431; Mature: 51299

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFK
CCCCCCEEEEEECCCCHHHHCCHHHCCCEEEHHHHHHHHHHHHHHCCHHHCCEECCCCCC
PSDLRELETCLSIQHIGWIAATRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHA
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HGMVALTEPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRVAATDAPVFISGESGTGKELT
CCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
AVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
EEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDL
EECCCCCCCCHHHHHHHHHHHCCHHHCCCEEECCCCEEEEEEHHCCHHHHHHCCCHHHHH
FHRLCVLKIEEPPLRARGKDIEVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNV
HHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRMITAADLELNDFATLAPVSLLEAREAAERQAIEQALLRHRGRF
HHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPLPELPHHAC
HHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GADQRHVIYYSREPNDALRGHFDECGWRVDLAETVRDVRRVVQHGVATAGLLDFSPGFK
CCCCCEEEEEECCCCHHHHCCHHHCCCEEEHHHHHHHHHHHHHHCCHHHCCEECCCCCC
PSDLRELETCLSIQHIGWIAATRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHA
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HGMVALTEPVAPPVGAGRSEGEMVGTCDAMLGLFRTIRRVAATDAPVFISGESGTGKELT
CCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
AVAIHERSSRAQAPFIAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
EEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMEAALREGRFREDL
EECCCCCCCCHHHHHHHHHHHCCHHHCCCEEECCCCEEEEEEHHCCHHHHHHCCCHHHHH
FHRLCVLKIEEPPLRARGKDIEVLARHMLERFKGDAHRRLRGFSPDAVASLYGYSWPGNV
HHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRMITAADLELNDFATLAPVSLLEAREAAERQAIEQALLRHRGRF
HHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPLPELPHHAC
HHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]