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The map label for this gene is udg [H]

Identifier: 78065636

GI number: 78065636

Start: 1099635

End: 1101035

Strand: Direct

Name: udg [H]

Synonym: Bcep18194_A4164

Alternate gene names: 78065636

Gene position: 1099635-1101035 (Clockwise)

Preceding gene: 78065635

Following gene: 78065637

Centisome position: 29.77

GC content: 66.17

Gene sequence:

>1401_bases
ATGAAAATCACCATCATCGGCACCGGCTATGTCGGTCTCGTCACGGGCGCCTGCCTCGCAGAGATCGGTCACGACGTCTT
CTGTCTCGACGTCGATCCGCGCAAGATCGACATCCTGAACAACGGCGGGATGCCGATTCACGAACCGGGGCTGCTGGACA
TCATCGCGCGCAACCGCGCGGCCGGGCGCCTGCGCTTCTCGACCGACATCGAGTCGAGCGTCGCGCACGGCGAGATCCAG
TTCATCGCCGTCGGCACGCCGCCCGACGAGGACGGCTCGGCCGACCTGCAGTACGTGCTCGAAGCCGCGCGCAACATCGG
CCGCCACATGACGGGCTTCAAGGTGATCGTCGACAAGTCGACGGTGCCGGTCGGCACTGCGCAGCGCGTGCGCGGCGTGG
TCGACGAGGCGCTTGCCGCCCGCGGTCTGGCAGGCAGCGTCGCGCATCGCTTCTCGGTCGTGTCGAACCCGGAGTTCCTG
AAGGAAGGCGCCGCGGTCGAAGACTTCATGCGTCCGGACCGGATTATCATCGGCGTCGACGACGACGAGACGGGTACGAT
CGCACGCGAGAAGATGAAGAAGCTTTACGCGCCGTTCAACCGCAACCACGAGCGCACGATCTACATGGACGTGCGTTCGG
CCGAGTTCGCGAAATATGCGGCGAATGCGATGCTCGCAACGCGCATTTCGTTCATGAACGAGATGTCGAATCTCGCCGAC
AAGGTCGGCGCGGACATCGAGGCCGTGCGCCGCGGGATCGGCTCCGATCCGCGCATCGGCTATCACTTCCTGTACGCCGG
CGTCGGCTACGGCGGCTCGTGCTTCCCGAAGGACGTCCAGGCGCTGATTCGCACCGCAGGCGAGAACGGCCAGCCGCTGC
GTATCCTGGAAGCCGTCGAAGCGGCCAACCATGCGCAGAAGGACGTGCTGATCGGCAAGATCGAGCAGCGTTTCGGCGCC
GACCTGACCGGCCGCGAGTTCGCGGTCTGGGGCCTGGCGTTCAAGCCGAACACCGACGACATGCGCGAGGCGCCGAGCCG
TCGCCTGATCGCCGCGCTGCTCGAACGCGGCGCGACCGTGCGTGCGTACGATCCGGTCGCGGTCGACGAGGCGCAGCGCG
TGTTTGCGCTCGATTTCGGCACCGATCCGGACACGCTGGCGCGGCTGCATCTCGTCGAGACGCAGGACATCGCCGTGACG
GGTGCGGACGCGCTCGTGATCGTGACCGAGTGGAAGGAATTCCGGAGCCCCGACTTCACGCGCCTGAAGGCCGAACTGAA
GGCGCCGGTGATCTTCGACGGGCGCAACCTCTACGAGCCGGATGCGATGGCCGAACTGGGCATCGACTACTACGCGATCG
GCCGGCCGTATGTCGATCCCCAGTCGTCCACCCGTGGCTGA

Upstream 100 bases:

>100_bases
GCCGGGCTGATCCCGGCACGCGGAGCCAACGCGCTGCGGTTGCCGCCGGGCTCGTCCCGGCGGCCAAGTTAGTCAATTAC
CGGGAAGTACCGGAACATCT

Downstream 100 bases:

>100_bases
CCACACGATGAATACTCTCCGCGAAGTCGTTCCGGTGCCGCGCGAACAGCTCGCGCGCTCGCGCGTGCTTGTCGTCGGCG
ACGTGATGCTCGACCGTTAC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRAAGRLRFSTDIESSVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTAQRVRGVVDEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVEDFMRPDRIIIGVDDDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIEQRFGA
DLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATVRAYDPVAVDEAQRVFALDFGTDPDTLARLHLVETQDIAVT
GADALVIVTEWKEFRSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSTRG

Sequences:

>Translated_466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRAAGRLRFSTDIESSVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTAQRVRGVVDEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVEDFMRPDRIIIGVDDDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIEQRFGA
DLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATVRAYDPVAVDEAQRVFALDFGTDPDTLARLHLVETQDIAVT
GADALVIVTEWKEFRSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSTRG
>Mature_466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRAAGRLRFSTDIESSVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTAQRVRGVVDEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVEDFMRPDRIIIGVDDDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIEQRFGA
DLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATVRAYDPVAVDEAQRVFALDFGTDPDTLARLHLVETQDIAVT
GADALVIVTEWKEFRSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSTRG

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=469, Percent_Identity=35.181236673774, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI296040438, Length=371, Percent_Identity=35.5795148247978, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI296040443, Length=312, Percent_Identity=36.8589743589744, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1788340, Length=381, Percent_Identity=28.0839895013123, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI48994968, Length=424, Percent_Identity=25.4716981132075, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17560350, Length=470, Percent_Identity=35.9574468085106, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17136908, Length=471, Percent_Identity=35.4564755838641, Blast_Score=252, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 50882; Mature: 50882

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCC
AGRLRFSTDIESSVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKS
CCEEEEECCCHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTAQRVRGVVDEALAARGLAGSVAHRFSVVSNPEFLKEGAAVEDFMRPDRIIIGVD
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCHHHHCCCCEEEEECC
DDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
CCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
AANHAQKDVLIGKIEQRFGADLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
RAYDPVAVDEAQRVFALDFGTDPDTLARLHLVETQDIAVTGADALVIVTEWKEFRSPDFT
EEECCCCCCCCCEEEEEECCCCHHHHHEEEEEECCCEEEECCCEEEEEEEHHHHCCCCHH
RLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSTRG
HHHHHHCCCEEECCCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCC
AGRLRFSTDIESSVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKS
CCEEEEECCCHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTAQRVRGVVDEALAARGLAGSVAHRFSVVSNPEFLKEGAAVEDFMRPDRIIIGVD
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCHHHHCCCCEEEEECC
DDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
CCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
AANHAQKDVLIGKIEQRFGADLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
RAYDPVAVDEAQRVFALDFGTDPDTLARLHLVETQDIAVTGADALVIVTEWKEFRSPDFT
EEECCCCCCCCCEEEEEECCCCHHHHHEEEEEECCCEEEECCCEEEEEEEHHHHCCCCHH
RLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSTRG
HHHHHHCCCEEECCCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]