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The map label for this gene is fbp [H]

Identifier: 78065597

GI number: 78065597

Start: 1054111

End: 1055124

Strand: Reverse

Name: fbp [H]

Synonym: Bcep18194_A4125

Alternate gene names: 78065597

Gene position: 1055124-1054111 (Counterclockwise)

Preceding gene: 78065598

Following gene: 78065596

Centisome position: 28.56

GC content: 64.0

Gene sequence:

>1014_bases
ATGTCCATTGCCCGCCGCACCACGCTGTCGAAGTTCCTGATCGAACAGCAACGTGAGACCAACAACCTCCCCGCCGACCT
GCGCCTGCTGATCGAAGTCGTCGCACGCGCGTGCAAGGCGATCAGCTACAACGTGTCGAAGGGCGCGCTTGGCGAAGCGC
TCGGCACCGCCGGCAGCGAGAACGTCCAGGGCGAAGTGCAGAAGAAGCTCGACATCCTGTCGAACGAGATCCTGCTCGAC
GCGAACGAATGGGGCGGCAACCTCGCCGCGATGGCATCGGAAGAAATGGAAACGTTCTTCCCGATCCCGGCGAACTACCC
GCGCGGCGAATACCTGCTCGTGTTCGATCCGCTCGACGGCTCGTCGAACATCGACGTGAACGTGTCGATCGGCACGATCT
TCTCGGTGCTGCGCTGCCCGGACGGCAAGCAGGCCACCGAGGAATCGTTCCTGCAGCCCGGCACGCAGCAGGTTGCGGCC
GGCTACGCCGTGTACGGCCCGCAGACGGTGTTCGTGCTGACGACCGGCAACGGCGTGAACTGCTTCACGCTCGACCGCGA
AGTCGGCTCGTGGGTGCTCACGCAGAGCAACATGCAGATCCCGGCCGACACGCGCGAATACGCGATCAACGCATCGAACG
CGCGTCACTGGTACGACCCGGTCAAGCGCTACGTCGACGAACTGAATGCCGGCAAGGACGGCCCGCGCGGCGACAACTTC
AACATGCGCTGGATCGCATCGATGGTGTCAGACGTGCACCGGATCCTGAACCGCGGCGGCGTCTTCATGTACCCGGCCGA
CAAGCGCACGCCGGATCGTCCGGGCAAGCTGCGCCTGATGTACGAAGCGAACCCGATGTCGTTCATCGTCGAGCAGGCAG
GCGGCGCCGCGACGACCGGCACGCAGCGCATCATGGAAGTGCAGCCGACAGGCCTGCATCAGCGCGTCCCGGTGTTCCTC
GGTTCGAAGAACGAAGTCGATCGCGTGACGGGCTACCACCAGGAAAAGCAATAA

Upstream 100 bases:

>100_bases
GCCCGGCCATGTAACCGGACGAAAAAACCCGGCGGCTCGGGAGGTGCGACGGGTAAAATTGCGGCCATTCAAGGATTCTT
TTGGCCTTCTGGAGTCTGTC

Downstream 100 bases:

>100_bases
ATTTGCACTGCAGCACTAGACAGTGTCGCGCGACGTACGTAGAATCGCGGCTCTCGATGTGACCCCACCGGGTCGTATCG
CAGTGAAACGAAGCGGGAAG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGEALGTAGSENVQGEVQKKLDILSNEILLD
ANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAA
GYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
NMRWIASMVSDVHRILNRGGVFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFL
GSKNEVDRVTGYHQEKQ

Sequences:

>Translated_337_residues
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGEALGTAGSENVQGEVQKKLDILSNEILLD
ANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAA
GYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
NMRWIASMVSDVHRILNRGGVFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFL
GSKNEVDRVTGYHQEKQ
>Mature_336_residues
SIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGEALGTAGSENVQGEVQKKLDILSNEILLDA
NEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAAG
YAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNFN
MRWIASMVSDVHRILNRGGVFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFLG
SKNEVDRVTGYHQEKQ

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=330, Percent_Identity=41.2121212121212, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI189083692, Length=319, Percent_Identity=41.692789968652, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI16579888, Length=319, Percent_Identity=41.692789968652, Blast_Score=249, Evalue=3e-66,
Organism=Escherichia coli, GI1790679, Length=330, Percent_Identity=43.3333333333333, Blast_Score=272, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17508131, Length=325, Percent_Identity=42.1538461538462, Blast_Score=269, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6323409, Length=335, Percent_Identity=38.8059701492537, Blast_Score=255, Evalue=7e-69,
Organism=Drosophila melanogaster, GI45550998, Length=325, Percent_Identity=43.6923076923077, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI19921562, Length=325, Percent_Identity=43.6923076923077, Blast_Score=263, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37198; Mature: 37067

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGEALGTAGSE
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCC
NVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDG
CCHHHHHHHHHHHCCEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCCEEEEEECCCC
SSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAAGYAVYGPQTVFVLTTGNGVN
CCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCEEEECCCEEEEEECCCCEE
CFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
EEEECCCCCCEEEECCCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NMRWIASMVSDVHRILNRGGVFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTG
CHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHEECCCCCCCCC
TQRIMEVQPTGLHQRVPVFLGSKNEVDRVTGYHQEKQ
CHHEEEECCCCCCCCCCEEECCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
SIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGEALGTAGSE
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCC
NVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDG
CCHHHHHHHHHHHCCEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCCEEEEEECCCC
SSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAAGYAVYGPQTVFVLTTGNGVN
CCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCEEEECCCEEEEEECCCCEE
CFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
EEEECCCCCCEEEECCCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NMRWIASMVSDVHRILNRGGVFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTG
CHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHEECCCCCCCCC
TQRIMEVQPTGLHQRVPVFLGSKNEVDRVTGYHQEKQ
CHHEEEECCCCCCCCCCEEECCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA