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The map label for this gene is mhpA [H]

Identifier: 78065595

GI number: 78065595

Start: 1050950

End: 1052683

Strand: Reverse

Name: mhpA [H]

Synonym: Bcep18194_A4123

Alternate gene names: 78065595

Gene position: 1052683-1050950 (Counterclockwise)

Preceding gene: 78065596

Following gene: 78065594

Centisome position: 28.5

GC content: 67.42

Gene sequence:

>1734_bases
ATGGATATCGACTTCAAGCCCTACCCGTTCGTCGCCGAGCGCCATCCCGCGCATCTGCCAGCCTGCGACGACAGTATCGA
TACGCACCGGCATCGCGTGGCGATCGTCGGCGGCGGCCCCGTCGGCCTCGCCGTCGCGCTCGGTCTCGCGAACCACGGTA
TCCACAGCGTGCTGATCGAGGCCGACGATGCGGTCTGCCACGGCAGCCGCGCCATCTGCATCTCGCGGCGCAGCCTCGAA
ATCATCGAGCGGCTCGGCGCGCTCGACGATTTCCTGCGCACGGGACTGCCGTGGACCGGCGGGCGCAGCTTCTACCGTCG
CGACGAAGTGCTGCATTTCACGATGCCGCAGGACGAAAACCAGAAGCTGCCGCCGATGATCAATCTCGCGCAGTATCACA
TCGAGCAGTTCCTGCTCGATGCCGTGCAGCGCCGCCCCGAACTCATCGAGATTCGCTGGCAGGCGAAAGTCACCGGCGTG
ACCCGGCAACCGGACGGTGTGCGCGTCGACGTCGACACGCCGCTCGGCGGCTACGCACTCGACGCCGCCTGGGTCGTCGC
GTGTGACGGCGGACGCAGCACGATGCGTGAAGCGCTCGGCCTGTCGCTGCAGGGCACGAGCTACGAGGGCCGCTACGTGA
TCGTCGACATCGCGCTCGACAGCGACCGGCCGACCGAACGGCTCGCGTACTTCGATCCGTCGTCGAACCCGGGCTCGACG
GTGCTCGTCCACAAGCAGCCCGACAACGTGTGGCGCATCGACTACCAGTTGCGCGACGATGAGGATCCCGAAGCGGCCGT
CAAGCCGGAGAACGTGATCCCGCGCGTGCAGAACCTGCTCGACATGATGGGCGAGCGCGGCGACTGGTCGCCGATCTGGA
TCACGATCTACAAGGCGAACGCGCTGACGCTCGAACGCTATCGGCACGGCCGCGTGCTGTTCTGCGGCGACGCCGCGCAT
CTCGTGCCGATCTTCGGCGTGCGCGGTGCGAATTCGGGCATCGACGATGCCGACAACCTTGCATGGAAACTCGCGTACGT
GACGCGCGGGCTCGCATCGGACACGCTGCTCGACAGCTACTCGGACGAACGCGTGTTCGCGACGCACGAGAACCTGCGCT
ACGGCACGAAGAGCACCGAGTTCATGGCGCCGCCGTCGTTTGCCTTCGAACTGATGCGCAAGGCCGTGCTGTCGCTCGCG
GTCCGGCATCCGGCGCTGCGCTCGCTGATCAATCCGCGCCAGACGACGGCGATCGCGTATGCAACGTCGCCGCTCAACGC
AGCCGAACGCGACACGTTTTCAGCCGGCCCCGCGCCCGGCACGGTGCTCGCCGAATGTCCGCTGATGCTGTACACGGCCC
ACGGCAGCGACATGCGCCGCGGCCACCTGACCGATCTCGTCGCCCCGCGCTTCACCGCGTTCTGCTTCACGTCCGACGGC
GAGCCCGATCCGGCGCTGGCCGATCTCGAACGGCGTCTGCAGGCTTCACGGATACCGTTCGCACTCGTCACGCTCGCACG
GCATGCGGCGCCGCAACAACCGCGCTGTGGCGGCCATGACGACGACGGCCGGCTGTTCGACATGTACGGCGCGCGCGACG
GCACCGTCTATCTCGTGCGTCCGGACGGTCACGTACTCGGCCGCTGGCACGACGCTCGCGCCAGCGACGTGACCGCCGCG
CTCGAACGCGCACTCCATCCGTGCGCATCAACCGATCCTCAGGAGACCGCATGA

Upstream 100 bases:

>100_bases
GGACAGCGGATTTCCGCCCGGCTTCCATACTGCTTCGACTGCCTGCACACGTTGCCCCGGCGCGCGTGCACGTCGAACTG
CCCTCCCCTGGAAGCCAACG

Downstream 100 bases:

>100_bases
TGACGGATACCGAACGCGACACGCTCTACACCGACCTGTGCCGCACGATGACGCGGATCGGCGAAGCCGATGCGTCGCTC
TTTCTCGCCCGCTTCGCGTG

Product: FAD-dependent oxidoreductase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase; Flavin-type monooxygenase [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MDIDFKPYPFVAERHPAHLPACDDSIDTHRHRVAIVGGGPVGLAVALGLANHGIHSVLIEADDAVCHGSRAICISRRSLE
IIERLGALDDFLRTGLPWTGGRSFYRRDEVLHFTMPQDENQKLPPMINLAQYHIEQFLLDAVQRRPELIEIRWQAKVTGV
TRQPDGVRVDVDTPLGGYALDAAWVVACDGGRSTMREALGLSLQGTSYEGRYVIVDIALDSDRPTERLAYFDPSSNPGST
VLVHKQPDNVWRIDYQLRDDEDPEAAVKPENVIPRVQNLLDMMGERGDWSPIWITIYKANALTLERYRHGRVLFCGDAAH
LVPIFGVRGANSGIDDADNLAWKLAYVTRGLASDTLLDSYSDERVFATHENLRYGTKSTEFMAPPSFAFELMRKAVLSLA
VRHPALRSLINPRQTTAIAYATSPLNAAERDTFSAGPAPGTVLAECPLMLYTAHGSDMRRGHLTDLVAPRFTAFCFTSDG
EPDPALADLERRLQASRIPFALVTLARHAAPQQPRCGGHDDDGRLFDMYGARDGTVYLVRPDGHVLGRWHDARASDVTAA
LERALHPCASTDPQETA

Sequences:

>Translated_577_residues
MDIDFKPYPFVAERHPAHLPACDDSIDTHRHRVAIVGGGPVGLAVALGLANHGIHSVLIEADDAVCHGSRAICISRRSLE
IIERLGALDDFLRTGLPWTGGRSFYRRDEVLHFTMPQDENQKLPPMINLAQYHIEQFLLDAVQRRPELIEIRWQAKVTGV
TRQPDGVRVDVDTPLGGYALDAAWVVACDGGRSTMREALGLSLQGTSYEGRYVIVDIALDSDRPTERLAYFDPSSNPGST
VLVHKQPDNVWRIDYQLRDDEDPEAAVKPENVIPRVQNLLDMMGERGDWSPIWITIYKANALTLERYRHGRVLFCGDAAH
LVPIFGVRGANSGIDDADNLAWKLAYVTRGLASDTLLDSYSDERVFATHENLRYGTKSTEFMAPPSFAFELMRKAVLSLA
VRHPALRSLINPRQTTAIAYATSPLNAAERDTFSAGPAPGTVLAECPLMLYTAHGSDMRRGHLTDLVAPRFTAFCFTSDG
EPDPALADLERRLQASRIPFALVTLARHAAPQQPRCGGHDDDGRLFDMYGARDGTVYLVRPDGHVLGRWHDARASDVTAA
LERALHPCASTDPQETA
>Mature_577_residues
MDIDFKPYPFVAERHPAHLPACDDSIDTHRHRVAIVGGGPVGLAVALGLANHGIHSVLIEADDAVCHGSRAICISRRSLE
IIERLGALDDFLRTGLPWTGGRSFYRRDEVLHFTMPQDENQKLPPMINLAQYHIEQFLLDAVQRRPELIEIRWQAKVTGV
TRQPDGVRVDVDTPLGGYALDAAWVVACDGGRSTMREALGLSLQGTSYEGRYVIVDIALDSDRPTERLAYFDPSSNPGST
VLVHKQPDNVWRIDYQLRDDEDPEAAVKPENVIPRVQNLLDMMGERGDWSPIWITIYKANALTLERYRHGRVLFCGDAAH
LVPIFGVRGANSGIDDADNLAWKLAYVTRGLASDTLLDSYSDERVFATHENLRYGTKSTEFMAPPSFAFELMRKAVLSLA
VRHPALRSLINPRQTTAIAYATSPLNAAERDTFSAGPAPGTVLAECPLMLYTAHGSDMRRGHLTDLVAPRFTAFCFTSDG
EPDPALADLERRLQASRIPFALVTLARHAAPQQPRCGGHDDDGRLFDMYGARDGTVYLVRPDGHVLGRWHDARASDVTAA
LERALHPCASTDPQETA

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=384, Percent_Identity=30.46875, Blast_Score=161, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 63779; Mature: 63779

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDFKPYPFVAERHPAHLPACDDSIDTHRHRVAIVGGGPVGLAVALGLANHGIHSVLIE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEE
ADDAVCHGSRAICISRRSLEIIERLGALDDFLRTGLPWTGGRSFYRRDEVLHFTMPQDEN
CCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCEEEEECCCCCC
QKLPPMINLAQYHIEQFLLDAVQRRPELIEIRWQAKVTGVTRQPDGVRVDVDTPLGGYAL
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECEECCCCEEEEECCCCCCEEE
DAAWVVACDGGRSTMREALGLSLQGTSYEGRYVIVDIALDSDRPTERLAYFDPSSNPGST
CEEEEEEECCCHHHHHHHHCCEEECCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCE
VLVHKQPDNVWRIDYQLRDDEDPEAAVKPENVIPRVQNLLDMMGERGDWSPIWITIYKAN
EEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECC
ALTLERYRHGRVLFCGDAAHLVPIFGVRGANSGIDDADNLAWKLAYVTRGLASDTLLDSY
EEEEEHHHCCCEEEECCCCCEEEEEEECCCCCCCCCCHHHEEEEEHHHCCCCHHHHHHCC
SDERVFATHENLRYGTKSTEFMAPPSFAFELMRKAVLSLAVRHPALRSLINPRQTTAIAY
CCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHEEEEE
ATSPLNAAERDTFSAGPAPGTVLAECPLMLYTAHGSDMRRGHLTDLVAPRFTAFCFTSDG
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHCCCEEEEEECCCC
EPDPALADLERRLQASRIPFALVTLARHAAPQQPRCGGHDDDGRLFDMYGARDGTVYLVR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEC
PDGHVLGRWHDARASDVTAALERALHPCASTDPQETA
CCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDIDFKPYPFVAERHPAHLPACDDSIDTHRHRVAIVGGGPVGLAVALGLANHGIHSVLIE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCEEEEEE
ADDAVCHGSRAICISRRSLEIIERLGALDDFLRTGLPWTGGRSFYRRDEVLHFTMPQDEN
CCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCEEEEECCCCCC
QKLPPMINLAQYHIEQFLLDAVQRRPELIEIRWQAKVTGVTRQPDGVRVDVDTPLGGYAL
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECEECCCCEEEEECCCCCCEEE
DAAWVVACDGGRSTMREALGLSLQGTSYEGRYVIVDIALDSDRPTERLAYFDPSSNPGST
CEEEEEEECCCHHHHHHHHCCEEECCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCE
VLVHKQPDNVWRIDYQLRDDEDPEAAVKPENVIPRVQNLLDMMGERGDWSPIWITIYKAN
EEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECC
ALTLERYRHGRVLFCGDAAHLVPIFGVRGANSGIDDADNLAWKLAYVTRGLASDTLLDSY
EEEEEHHHCCCEEEECCCCCEEEEEEECCCCCCCCCCHHHEEEEEHHHCCCCHHHHHHCC
SDERVFATHENLRYGTKSTEFMAPPSFAFELMRKAVLSLAVRHPALRSLINPRQTTAIAY
CCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHEEEEE
ATSPLNAAERDTFSAGPAPGTVLAECPLMLYTAHGSDMRRGHLTDLVAPRFTAFCFTSDG
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHCCCEEEEEECCCC
EPDPALADLERRLQASRIPFALVTLARHAAPQQPRCGGHDDDGRLFDMYGARDGTVYLVR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEC
PDGHVLGRWHDARASDVTAALERALHPCASTDPQETA
CCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA