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The map label for this gene is glpR [H]

Identifier: 78065515

GI number: 78065515

Start: 968143

End: 968898

Strand: Reverse

Name: glpR [H]

Synonym: Bcep18194_A4043

Alternate gene names: 78065515

Gene position: 968898-968143 (Counterclockwise)

Preceding gene: 78065521

Following gene: 78065514

Centisome position: 26.23

GC content: 70.37

Gene sequence:

>756_bases
ATGTTGACGACACAACGCAAGAAAGCGATCCTCGACGCACTCGCGCGCGACGGCCAGGTGCTGGCGGTCGAGCTGAGCGC
GCAATTCGGCGTGTCCGAAGACACGGTCCGCCGCGACCTGCGCGAGCTCGCGGCCGAAGGCCTGCTGCAGCGCGTGCATG
GCGGCGCGCTGCCGGCGTCGCCGGCCATTGCGCCGTTCGCGCAGCGCGAGGCGCTCGAGACGGCGGAAAAGCGGCGCATC
GCGCGGCGGGCCGCGGAGATGATCGCGCCCGGGCAGGTAGCGATCGTCGACGGCGGCACGACCTCGGCGCTGCTCGTCAG
CCAGTTGCCGGCCGACCTGCGTGCGACGATCGTCACGCACAGCCCGAGTGTCGCGGTGGCGCTGGCCGCGCATCCATCGA
TCGACGTGATCCTGATCGGCGGGCGGCTCTACAAGCATTCGATCGTCGCCGTCGGCGCGGCGGCGATGGAAGGCATTGCG
CGCATCCATGCGGACCTGTACTTCATGGGCGTCACGGGCGTGCATCCGGTCGCGGGGCTCAGCACCGGCGATTTCGAGGA
AGCGGCGATCAAGCGCGCGCTCGCCGAACGCGCGGCCGAGACGGTCGTGCTCGCGTCGCAGTCGAAGCTGCGCGCGGCGT
CGCAGTTCGTGATCGGCGAGCTCACGCTGGCGCACACCGTGGTGGTCGAAAAGGAAACCGACGCCGCGCTGACGAAGCCT
ATTGAGGCGGCAGGCGTGACGGTCGTGCGCGCGTAG

Upstream 100 bases:

>100_bases
GGTCCCGCGTTGCAGCCATCCCAGCCTCCGGTTCGACAAAAGACGGCGCCCATGGTAACGTGCATATTCGTGCAACTTCA
AGAAAATTCGTGCAGACACG

Downstream 100 bases:

>100_bases
CGGCGGCGGGGTGCGCCCGCGCGGGGTGTGCGGGGTGTGCGGGGTGTGCGGGGTGTGCGGGGTGTGCGGGGTGTGCGGGG
TGTGCGGGGTGTGCGGGATG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLTTQRKKAILDALARDGQVLAVELSAQFGVSEDTVRRDLRELAAEGLLQRVHGGALPASPAIAPFAQREALETAEKRRI
ARRAAEMIAPGQVAIVDGGTTSALLVSQLPADLRATIVTHSPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIA
RIHADLYFMGVTGVHPVAGLSTGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGELTLAHTVVVEKETDAALTKP
IEAAGVTVVRA

Sequences:

>Translated_251_residues
MLTTQRKKAILDALARDGQVLAVELSAQFGVSEDTVRRDLRELAAEGLLQRVHGGALPASPAIAPFAQREALETAEKRRI
ARRAAEMIAPGQVAIVDGGTTSALLVSQLPADLRATIVTHSPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIA
RIHADLYFMGVTGVHPVAGLSTGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGELTLAHTVVVEKETDAALTKP
IEAAGVTVVRA
>Mature_251_residues
MLTTQRKKAILDALARDGQVLAVELSAQFGVSEDTVRRDLRELAAEGLLQRVHGGALPASPAIAPFAQREALETAEKRRI
ARRAAEMIAPGQVAIVDGGTTSALLVSQLPADLRATIVTHSPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIA
RIHADLYFMGVTGVHPVAGLSTGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGELTLAHTVVVEKETDAALTKP
IEAAGVTVVRA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=231, Percent_Identity=32.9004329004329, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789519, Length=251, Percent_Identity=30.6772908366534, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787540, Length=244, Percent_Identity=29.5081967213115, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87082344, Length=245, Percent_Identity=28.9795918367347, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=29.0598290598291, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789170, Length=237, Percent_Identity=29.1139240506329, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789059, Length=247, Percent_Identity=28.3400809716599, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI226510968, Length=211, Percent_Identity=29.3838862559242, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787063, Length=233, Percent_Identity=26.1802575107296, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=25.1968503937008, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790753, Length=235, Percent_Identity=25.1063829787234, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26181; Mature: 26181

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTQRKKAILDALARDGQVLAVELSAQFGVSEDTVRRDLRELAAEGLLQRVHGGALPAS
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAIAPFAQREALETAEKRRIARRAAEMIAPGQVAIVDGGTTSALLVSQLPADLRATIVTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEC
SPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIARIHADLYFMGVTGVHPVAGL
CCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
STGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGELTLAHTVVVEKETDAALTKP
CCCCHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHCC
IEAAGVTVVRA
HHHCCEEEEEC
>Mature Secondary Structure
MLTTQRKKAILDALARDGQVLAVELSAQFGVSEDTVRRDLRELAAEGLLQRVHGGALPAS
CCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAIAPFAQREALETAEKRRIARRAAEMIAPGQVAIVDGGTTSALLVSQLPADLRATIVTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEC
SPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIARIHADLYFMGVTGVHPVAGL
CCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
STGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGELTLAHTVVVEKETDAALTKP
CCCCHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHCC
IEAAGVTVVRA
HHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]