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The map label for this gene is pgm [H]

Identifier: 78065464

GI number: 78065464

Start: 916941

End: 918335

Strand: Direct

Name: pgm [H]

Synonym: Bcep18194_A3990

Alternate gene names: 78065464

Gene position: 916941-918335 (Clockwise)

Preceding gene: 78065458

Following gene: 78065465

Centisome position: 24.82

GC content: 66.81

Gene sequence:

>1395_bases
ATGATCTCCCAATCCATCTTCAAGGCATATGACATTCGTGGTGTGGTCGGCAAGACGCTCGACACCGACACCGCGCGCGC
GATCGGCCGGGCGTTCGGCAGCGAAGTGCGCGCGCAGGGCGGCGATGCGGTGGTCGTCGCGCGCGACGGCCGCCTGTCCG
GGCCGGACCTCGTCGGCGCGCTGGCCGACGGCCTGCGTGCGGCGGGCGTCGACGTCGTCGACGTCGGCATGGTGCCCACG
CCGGTCGGCTATTTCGCGGCGAACGTCCCGCTCGCGCTGAAGGACGGCGAGCGCCGCGTCGATTCGTGCATCGTCGTCAC
GGGCAGCCACAACCCGCCCGACTACAACGGCTTCAAGATGGTGCTGCGCGGCGCCGCGATCTACGGCGAGCAGATCCAGG
CGCTGTATCAGCGCATCGTCGACGAGCGTTTCGAGACGGGCAACGGCTCGTACGAACAGTTCGACGTGGCCGATCAATAC
ATCGCACGCATCGTCGGCGACATCAAGCCGGCCCGCCCGATGAAGCTCGTCGTCGACGCCGGCAACGGCGTGGCCGGCCC
GCTCGCGACGCGCCTGTTCAAGGCGCTCGGCTGCGAGCTGGTGGAGCGTTTCACCGACATCGACGGCACGTTCCCGAACC
ATCACCCCGATCCCGCCCACCCGGAAAACCTGCAGGACGTGATCCAGGCGCTGAAGGACACCGACGCCGAGATCGGCTTC
GCGTTCGACGGCGATGGCGACCGGCTCGGCGTCGTCACGAAGGATGGCCAGATCATCTATCCGGACCGCCAGCTGATGCT
GTTCGCGGAAGAGGTGCTGTCGCGCAACCCGGGCGCGCAGATCATCTATGACGTGAAGTGCACGCGCCACCTCGCGCAGT
GGATCAAGTCGAAGGGTGGCGAGCCGCTGATGTGGAAGACGGGCCACTCGCTCGTGAAGGCGAAGCTGCGCGAGACGGGT
GCGCCGCTCGCCGGCGAAATGAGCGGCCACGTGTTCTTCAAGGATCGCTGGTACGGCTTCGACGACGGTCTCTACACGGG
CGCACGCCTGCTCGAGATCCTCACGAAGACGGCCGATCCGAGCGCGCTGCTGAACGGGCTGCCGGACGCGATGAGCACGC
CCGAACTGCAGCTGTGGCTCGACGAAGGCGAGAACTTCCGCCTGATCGACAAGCTGCAGAAAGAGGCGAAGTTCGACGGT
GCAGAGGAAGTCGTGACGATCGACGGCCTGCGTGTCGAGTACCCGGACGGCTTCGGCCTCGCGCGTTCGTCGAACACGAC
GCCGGTCGTCGTGATGCGTTTCGAGTCGGAGACGCAGGAAGGGCTCAAGCGCATCCAGGAGGACTTCCGCCGCGTGCTGA
CGGCCGCGAAGCCGGACGTCAAGCTGCCGTTCTGA

Upstream 100 bases:

>100_bases
CACTCCGTGCCGGGCCAGCCTGTATCATGCGCGGCACCGGCGAGCGGCGGCCAGGCAAGCCAGACAATTTTCCATGCACG
CAACTGAGAGAAGAGAATCG

Downstream 100 bases:

>100_bases
GTGCAGGTGGCGGCGCGGCCGCCACTGGTGCTAAACGCCCCCAGGGCTCGGTCCGAAAAGCGGCGCACGCGCATCGCGTG
AGGCCGCTTTTCGCACTGTG

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MISQSIFKAYDIRGVVGKTLDTDTARAIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGALADGLRAAGVDVVDVGMVPT
PVGYFAANVPLALKDGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYQRIVDERFETGNGSYEQFDVADQY
IARIVGDIKPARPMKLVVDAGNGVAGPLATRLFKALGCELVERFTDIDGTFPNHHPDPAHPENLQDVIQALKDTDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWIKSKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILTKTADPSALLNGLPDAMSTPELQLWLDEGENFRLIDKLQKEAKFDG
AEEVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFESETQEGLKRIQEDFRRVLTAAKPDVKLPF

Sequences:

>Translated_464_residues
MISQSIFKAYDIRGVVGKTLDTDTARAIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGALADGLRAAGVDVVDVGMVPT
PVGYFAANVPLALKDGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYQRIVDERFETGNGSYEQFDVADQY
IARIVGDIKPARPMKLVVDAGNGVAGPLATRLFKALGCELVERFTDIDGTFPNHHPDPAHPENLQDVIQALKDTDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWIKSKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILTKTADPSALLNGLPDAMSTPELQLWLDEGENFRLIDKLQKEAKFDG
AEEVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFESETQEGLKRIQEDFRRVLTAAKPDVKLPF
>Mature_464_residues
MISQSIFKAYDIRGVVGKTLDTDTARAIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGALADGLRAAGVDVVDVGMVPT
PVGYFAANVPLALKDGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYQRIVDERFETGNGSYEQFDVADQY
IARIVGDIKPARPMKLVVDAGNGVAGPLATRLFKALGCELVERFTDIDGTFPNHHPDPAHPENLQDVIQALKDTDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWIKSKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILTKTADPSALLNGLPDAMSTPELQLWLDEGENFRLIDKLQKEAKFDG
AEEVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFESETQEGLKRIQEDFRRVLTAAKPDVKLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=451, Percent_Identity=36.1419068736142, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1789566, Length=477, Percent_Identity=27.4633123689727, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 50699; Mature: 50699

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISQSIFKAYDIRGVVGKTLDTDTARAIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGA
CCCHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LADGLRAAGVDVVDVGMVPTPVGYFAANVPLALKDGERRVDSCIVVTGSHNPPDYNGFKM
HHHHHHHCCCCEEECCCCCCCHHHHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHH
VLRGAAIYGEQIQALYQRIVDERFETGNGSYEQFDVADQYIARIVGDIKPARPMKLVVDA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEC
GNGVAGPLATRLFKALGCELVERFTDIDGTFPNHHPDPAHPENLQDVIQALKDTDAEIGF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEE
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWIKSKGG
EECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCC
EPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILTKTADP
CCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCH
SALLNGLPDAMSTPELQLWLDEGENFRLIDKLQKEAKFDGAEEVVTIDGLRVEYPDGFGL
HHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEECCCCCCC
ARSSNTTPVVVMRFESETQEGLKRIQEDFRRVLTAAKPDVKLPF
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISQSIFKAYDIRGVVGKTLDTDTARAIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGA
CCCHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LADGLRAAGVDVVDVGMVPTPVGYFAANVPLALKDGERRVDSCIVVTGSHNPPDYNGFKM
HHHHHHHCCCCEEECCCCCCCHHHHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHH
VLRGAAIYGEQIQALYQRIVDERFETGNGSYEQFDVADQYIARIVGDIKPARPMKLVVDA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEC
GNGVAGPLATRLFKALGCELVERFTDIDGTFPNHHPDPAHPENLQDVIQALKDTDAEIGF
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEE
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWIKSKGG
EECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCC
EPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILTKTADP
CCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCH
SALLNGLPDAMSTPELQLWLDEGENFRLIDKLQKEAKFDGAEEVVTIDGLRVEYPDGFGL
HHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEECCCCCCC
ARSSNTTPVVVMRFESETQEGLKRIQEDFRRVLTAAKPDVKLPF
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]