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The map label for this gene is galE [H]

Identifier: 78065460

GI number: 78065460

Start: 912373

End: 913395

Strand: Reverse

Name: galE [H]

Synonym: Bcep18194_A3986

Alternate gene names: 78065460

Gene position: 913395-912373 (Counterclockwise)

Preceding gene: 78065461

Following gene: 78065459

Centisome position: 24.73

GC content: 66.57

Gene sequence:

>1023_bases
ATGACCGCTAAAGGCACCATCCTCGTTACCGGCGGCGCGGGCTACATCGGCTCGCACACCGCCGTCGAGCTGCTCGACAA
CGGCTACGATGTCGTGATCGTCGACAACCTCGTCAACAGCAAGGCCGAATCCGTGCGCCGCATCGAGCGGATCACGGGCA
AGACGCCCGCGTTCCATCAGGTCGACGTGTGCGACGAAGCCGCGCTCGCCAAGGTATTCGATGCACACCCGATCACCGGC
ACGATCCATTTCGCGGCGCTCAAGGCCGTCGGCGAATCGGTCGCAAAGCCGCTCGAGTACTACCAGAACAACATCGGCGG
CCTGCTCGCCGTGCTCAAGGTGATGCGCGAGCGCAACGTCAGGCAGTTCGTGTTCAGTTCGTCCGCGACCGTGTACGGCG
TGCCCGAGCGCTCGCCGATCGACGAATCGTTCCCGCTGTCCGCGACGAACCCGTACGGCCAGTCGAAGCTGATCGCCGAG
CAGATCCTGCGCGATCTCGAGGTTTCCGACCCGTCGTGGCGAATCGCCACGCTGCGCTACTTCAACCCGGTCGGCGCGCA
CGCGAGCGGGCTGATCGGCGAGGATCCGGCCGGCATCCCGAACAACCTGATGCCGTATGTCGCGCAGGTCGCGGTCGGCA
AGCTGGAGCGGCTGCGCGTGTTCGGCTCCGACTACGCGACACCGGACGGCACCGGCGTGCGCGACTACATCCACGTCGTC
GATCTGGCGAAGGGGCACATCGCCGCGCTCGACGCGCTCGCGAAACGCGACGCGAGCTTCATCGTGAACCTCGGCACGGG
CCAGGGCTACAGCGTGCTGGAAGTCGTGCGCGCGTTCGAAAAGGCGTCGGGCCGCCCGGTGCCGTACGAGCTCGTCGCGC
GCCGCCCGGGCGACATCGCCGAGTGCTATGCGAACCCGCAGGCCGCGGCCGACATCATCGGCTGGCGCGCGACGCTCGGC
ATCGAAGAAATGTGTGCCGATCACTGGCGATGGCAGGAGGGGAACCCGCGCGGTTTTGTATAA

Upstream 100 bases:

>100_bases
CAAGGTCGCGTCGGAGTTCGACGAGCAACAGGTCGTCGAGCGCTATAGGGAGACCATCCATTCGTTGACCGGATTCACAC
TCTGAAGGAGCGCATCTGCA

Downstream 100 bases:

>100_bases
TCCGCTGTCCATTTTTCGAGCGATCCCATGCTCAGCTTCGCGTCCGGCTTTATCGTCTCCCTGCTCGTCACGCTGTTCAT
CGTGCGCTATGCGCACCTTC

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQVDVCDEAALAKVFDAHPITG
TIHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNVRQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAE
QILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLERLRVFGSDYATPDGTGVRDYIHVV
DLAKGHIAALDALAKRDASFIVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIAECYANPQAAADIIGWRATLG
IEEMCADHWRWQEGNPRGFV

Sequences:

>Translated_340_residues
MTAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQVDVCDEAALAKVFDAHPITG
TIHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNVRQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAE
QILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLERLRVFGSDYATPDGTGVRDYIHVV
DLAKGHIAALDALAKRDASFIVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIAECYANPQAAADIIGWRATLG
IEEMCADHWRWQEGNPRGFV
>Mature_339_residues
TAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQVDVCDEAALAKVFDAHPITGT
IHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNVRQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQ
ILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLERLRVFGSDYATPDGTGVRDYIHVVD
LAKGHIAALDALAKRDASFIVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIAECYANPQAAADIIGWRATLGI
EEMCADHWRWQEGNPRGFV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=57.6470588235294, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=57.6470588235294, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=57.6470588235294, Blast_Score=417, Evalue=1e-117,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=28.1021897810219, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=55.9880239520958, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI48994969, Length=255, Percent_Identity=27.843137254902, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=25.6906077348066, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=55.9766763848396, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=55.6521739130435, Blast_Score=391, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI115532424, Length=339, Percent_Identity=23.8938053097345, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=54.9707602339181, Blast_Score=375, Evalue=1e-105,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=55.6851311953353, Blast_Score=391, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36791; Mature: 36660

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQ
CCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCEE
VDVCDEAALAKVFDAHPITGTIHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQILRDLEVSDPSWRIATLRY
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
FNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLERLRVFGSDYATPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
DLAKGHIAALDALAKRDASFIVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIA
HHCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHH
ECYANPQAAADIIGWRATLGIEEMCADHWRWQEGNPRGFV
HHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKTPAFHQ
CCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCEE
VDVCDEAALAKVFDAHPITGTIHFAALKAVGESVAKPLEYYQNNIGGLLAVLKVMRERNV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQILRDLEVSDPSWRIATLRY
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
FNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLERLRVFGSDYATPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
DLAKGHIAALDALAKRDASFIVNLGTGQGYSVLEVVRAFEKASGRPVPYELVARRPGDIA
HHCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHH
ECYANPQAAADIIGWRATLGIEEMCADHWRWQEGNPRGFV
HHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]