Click here to switch to the map view.

The map label for this gene is ahpC [C]

Identifier: 78065379

GI number: 78065379

Start: 817614

End: 818252

Strand: Direct

Name: ahpC [C]

Synonym: Bcep18194_A3905

Alternate gene names: 78065379

Gene position: 817614-818252 (Clockwise)

Preceding gene: 78065375

Following gene: 78065381

Centisome position: 22.13

GC content: 61.03

Gene sequence:

>639_bases
ATGAGTCTGCGTCTTGGCGACATCGCACCGGATTTCGAGCAGGAATCGAGCCTGGGCCCGATCAAGTTTCACGAGTGGCT
GGGCGACGGCTGGGGTGTCCTGTTCTCCCATCCGGCCGACTACACGCCGGTGTGCACGACCGAACTCGGGCTGACCTCGA
AGCTGAAGGGCGAATTCGAGAAGCGCAACGTCAAAGTGATCGCGCTGTCGGTCGACGGCGTCGAATCGCACAAGGGCTGG
ATCAACGACATCAACGAAACGCAGTCGACGGTCGTCGGTTTCCCGATCATCGCCGATGCGGACCGCAAGGTTTCGCAGCT
GTACGACATGATCCACCCGAACGCGAACGAAACGCTGACGGTGCGTTCGCTGTTCGTGATCGACCCGAACAAGAAGGTGC
GACTGACCATCACGTACCCGGCCAGCACGGGGCGCAACTTCGACGAAGTGCTGCGCGTAATCGACTCGCTGCAACTGACC
GACAACTACAAGGTCGCGACGCCCGGCAACTGGAAGGATGGCGACGACGTCGTGATCGTGCCGTCGCTGCAGGATCCGGA
AGAGCTGAAGAAGCGCTTCCCGAAGGGCTTCAACGCGGTGCGTCCGTATCTGCGCCTCACGCCGCAGCCGAACAAGTAA

Upstream 100 bases:

>100_bases
AATAATCGTTCGCACGCCCCATTGCTTCCCGTAAGCTGACAGACTTTCCCGCGCCGATCCGGGCGCGGTTTCAACCAGCA
TCGTTCGAGGAGGGAACATC

Downstream 100 bases:

>100_bases
GCAACGGCTGCACATCAACGCGATACCGGGCCGGCGGCCCGGTGCACGGATCAGATGAAAAACGGCCCGCCCGGCAGTCA
TGCCGGGCGGGCCGTGTCTT

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRLGDIAPDFEQESSLGPIKFHEWLGDGWGVLFSHPADYTPVCTTELGLTSKLKGEFEKRNVKVIALSVDGVESHKGW
INDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLTVRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLT
DNYKVATPGNWKDGDDVVIVPSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK

Sequences:

>Translated_212_residues
MSLRLGDIAPDFEQESSLGPIKFHEWLGDGWGVLFSHPADYTPVCTTELGLTSKLKGEFEKRNVKVIALSVDGVESHKGW
INDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLTVRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLT
DNYKVATPGNWKDGDDVVIVPSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK
>Mature_211_residues
SLRLGDIAPDFEQESSLGPIKFHEWLGDGWGVLFSHPADYTPVCTTELGLTSKLKGEFEKRNVKVIALSVDGVESHKGWI
NDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLTVRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLTD
NYKVATPGNWKDGDDVVIVPSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=221, Percent_Identity=52.4886877828054, Blast_Score=228, Evalue=4e-60,
Organism=Homo sapiens, GI32189392, Length=190, Percent_Identity=32.1052631578947, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=32.1052631578947, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=32.1052631578947, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=32.1052631578947, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI5453549, Length=164, Percent_Identity=31.7073170731707, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI32483377, Length=164, Percent_Identity=31.7073170731707, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI5802974, Length=164, Percent_Identity=31.7073170731707, Blast_Score=81, Evalue=8e-16,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=31.1688311688312, Blast_Score=74, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=191, Percent_Identity=43.979057591623, Blast_Score=162, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI193204376, Length=192, Percent_Identity=30.7291666666667, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32565831, Length=192, Percent_Identity=30.7291666666667, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554494, Length=159, Percent_Identity=30.8176100628931, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=54.7169811320755, Blast_Score=229, Evalue=4e-61,
Organism=Saccharomyces cerevisiae, GI6323613, Length=157, Percent_Identity=31.2101910828025, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=160, Percent_Identity=30.625, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=49.3150684931507, Blast_Score=214, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=51.9417475728155, Blast_Score=207, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=51.9417475728155, Blast_Score=206, Evalue=8e-54,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=51.9417475728155, Blast_Score=206, Evalue=9e-54,
Organism=Drosophila melanogaster, GI17738015, Length=200, Percent_Identity=33, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17157991, Length=174, Percent_Identity=32.183908045977, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24641739, Length=174, Percent_Identity=32.183908045977, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24656348, Length=192, Percent_Identity=32.8125, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864676, Length=192, Percent_Identity=32.8125, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357347, Length=176, Percent_Identity=28.4090909090909, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23779; Mature: 23648

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDIAPDFEQESSLGPIKFHEWLGDGWGVLFSHPADYTPVCTTELGLTSKLKGEFE
CCCCCCCCCCCCCCCCCCCCEEHHHHHCCCCEEEECCCCCCCCEEEECCCCCHHHCCCHH
KRNVKVIALSVDGVESHKGWINDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLT
HCCEEEEEEEECCCCCCCCCCCCCCCCHHEEEECEEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLTDNYKVATPGNWKDGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEECCCCEEEECCCCCCCCCCEEEE
PSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK
CCCCCHHHHHHHCCCCCHHHCHHEEECCCCCC
>Mature Secondary Structure 
SLRLGDIAPDFEQESSLGPIKFHEWLGDGWGVLFSHPADYTPVCTTELGLTSKLKGEFE
CCCCCCCCCCCCCCCCCCCEEHHHHHCCCCEEEECCCCCCCCEEEECCCCCHHHCCCHH
KRNVKVIALSVDGVESHKGWINDINETQSTVVGFPIIADADRKVSQLYDMIHPNANETLT
HCCEEEEEEEECCCCCCCCCCCCCCCCHHEEEECEEEECCCHHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKVRLTITYPASTGRNFDEVLRVIDSLQLTDNYKVATPGNWKDGDDVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEECCCCEEEECCCCCCCCCCEEEE
PSLQDPEELKKRFPKGFNAVRPYLRLTPQPNK
CCCCCHHHHHHHCCCCCHHHCHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]