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The map label for this gene is pabB [H]

Identifier: 78065315

GI number: 78065315

Start: 748041

End: 749975

Strand: Direct

Name: pabB [H]

Synonym: Bcep18194_A3841

Alternate gene names: 78065315

Gene position: 748041-749975 (Clockwise)

Preceding gene: 78065314

Following gene: 78065322

Centisome position: 20.25

GC content: 68.48

Gene sequence:

>1935_bases
ATGACTGAAGGTAACGAGAGCGCGTCGTTCGCGCTCTTGGACGATTGCGACTCGACCGCGCTCGCGCGGTCGAGTCGTTT
GTATTCGGGGTTCGTGCGCGAACGTGTGTGCACGGATCCGGCTCGACTCGACGAGGTCGACGCAGCCGTGGCGCAGGATC
TGCGCGACGGGCTGCATGCGGTCGTCGTCGGCGATTACGAATTCGGACGCAATCTGCAACGAGCGCAGCCGGGCCATGCC
CCGCTGCGCTTTTTGCTGTTTGCGCGCTGCGAGCGCCTGTCGCGGGACGAAGTCGACGCGTGGCTCGCGCAGCGGGACGG
CGGCGGCACGCCGTCGATCGCGGGCGTCGCGCATGTCGCGAAGAGCGTGTCGCGCGATGCGTTCGACGTGGCGATCGCCG
CGGTGCACGACGCGCTGCGCGCAGGCGATTCGTATCAGGTCAACTACACGTACCGGCTGAACTTCGACGTGTTCGGCACG
CCGCTCGCGCTGTACCGGCGGCTGCGTGCGCGTCAGCCCGTGCGCTACGGTGCGCTGATCGCGTTGCCCGACGGCACGTG
GGTCGTGTCGTGCTCGCCCGAGCTGTTCGTCGAGAAGTACGGCGACGTGCTGCGCGCGCGGCCGATGAAGGGCACCGCGC
CACGTTCGGCCGACCCGCGCGACGATGCGGCCGCGGCCACGTTCCTTGCGAACGATCCGAAGAACCGCGCGGAAAACGTG
ATGATCGTCGACTTGCTGCGCAACGACGTGTCGCGGATCGCGCGCACCGGGACGGTCCGCGTGCCGGCGCTGTTCTCCGT
CGAGCCGTATGCGTCGGTGTGGCAGATGACGTCGACGGTCGAGGCCGGCTGGCGCGACGGAACGACGTTCGCGCAGATGC
TGCGCGCGCTGTTTCCGTGCGGATCGATCACGGGCGCGCCGAAGCACAAGACGATGCAGCTGATCGATGCGATCGAGTCG
ACGCCGCGCGGGCTCTATACGGGCGCGATCGGCTGGCTTGACGCTGCGAAACAAGGCGCGGATTCCGACGCGCCAGGTGA
TCGCCTGGCAGGTTGCGGCGATTTTTGCCTGTCGGTCGCGATCCGTACGTTGACGCTCGATGCGGCCGGCGAAGGCGATG
ATCGTGGAGGTGCAACGCGAGCCGACGTCGAAGCACGCCAACCGGCAACGGCAATCGCCGGCCGGCGCCGCGGCACGATG
GGTGTCGGCGCGGGCATCGTGCTCGACAGTGTCGCGGCCGACGAATATGCGGAGTGCGAATTGAAAGCGCGATTCCTGAC
GGATGCCGATCCCGGCTTCCAGCTGTTCGAAACGACTGCCGCCACGCGTGCGGACGGCATACGGCATCTCGATCGCCATC
TCGCGCGGCTGCAGCGTAGCGCGGATGCGTTCGGCTTCCGTTTCGACACCGATGCATTGCGTCGCGAGATCGACGCGCGT
TGTGCGGCGCTCGACGGCGACGGCGCATACCGGATGAAGCTCTCGCTCGCGAAGGACGGCACGATCGAGATCGTCGCGGC
ACCGCTCAAGCCGCTGCCGGCGGGGCCGGTCGGCGTGCTGCTGGCGTCCGCGCACGGCTTCGCACCGACCCGTACGAGCG
ATGCGCTGCTGCTGCACAAGACCACACGCCGCGCCGAATACGATCGCGCGTGGCAGGCGGCGGAGGCGCTTGGCGGCTTC
GACATGCTGTTCGTCAACGAGCGCGGCGAGGTGACGGAAGGCGGGCGCTCGAACCTGTTCGTGAAGCTCGACGGCCAGTG
GGTGACGCCGCCGCTCGAGTCGGGCGTGCTGCCGGGCGTGATGCGCGGCGTGCTGCTCGACGATCGTGCGTTCAGCGCGA
CGGAGCGGGTCGTGACCCGCGACGATCTCGCGCGTGCGGAGGCGCTGCTGCTGACCAACGCGCTACGCGGCGCGCTCGAC
GCGGTACTGAAGTGA

Upstream 100 bases:

>100_bases
TTCGAGAAGTCGCTGGCCGAGGGCGGCGCGCGTCACAGCCCGCAGAGCAAGAGCTGGTTCGACCGTGTGAAGAGCTTCTT
CGAGTAACTCGAGTAACAGC

Downstream 100 bases:

>100_bases
AATAACCGCCAGATAATCGATCAGCGCTGGCAGCGCAGGAAAGAAAAAGCGCGGCGCCCCGCAAAGGGCGCCGCGCTTTT
TTCATCGAGGCGCAGGCAAA

Product: anthranilate synthase component I/chorismate-binding protein

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MTEGNESASFALLDDCDSTALARSSRLYSGFVRERVCTDPARLDEVDAAVAQDLRDGLHAVVVGDYEFGRNLQRAQPGHA
PLRFLLFARCERLSRDEVDAWLAQRDGGGTPSIAGVAHVAKSVSRDAFDVAIAAVHDALRAGDSYQVNYTYRLNFDVFGT
PLALYRRLRARQPVRYGALIALPDGTWVVSCSPELFVEKYGDVLRARPMKGTAPRSADPRDDAAAATFLANDPKNRAENV
MIVDLLRNDVSRIARTGTVRVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPCGSITGAPKHKTMQLIDAIES
TPRGLYTGAIGWLDAAKQGADSDAPGDRLAGCGDFCLSVAIRTLTLDAAGEGDDRGGATRADVEARQPATAIAGRRRGTM
GVGAGIVLDSVAADEYAECELKARFLTDADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDTDALRREIDAR
CAALDGDGAYRMKLSLAKDGTIEIVAAPLKPLPAGPVGVLLASAHGFAPTRTSDALLLHKTTRRAEYDRAWQAAEALGGF
DMLFVNERGEVTEGGRSNLFVKLDGQWVTPPLESGVLPGVMRGVLLDDRAFSATERVVTRDDLARAEALLLTNALRGALD
AVLK

Sequences:

>Translated_644_residues
MTEGNESASFALLDDCDSTALARSSRLYSGFVRERVCTDPARLDEVDAAVAQDLRDGLHAVVVGDYEFGRNLQRAQPGHA
PLRFLLFARCERLSRDEVDAWLAQRDGGGTPSIAGVAHVAKSVSRDAFDVAIAAVHDALRAGDSYQVNYTYRLNFDVFGT
PLALYRRLRARQPVRYGALIALPDGTWVVSCSPELFVEKYGDVLRARPMKGTAPRSADPRDDAAAATFLANDPKNRAENV
MIVDLLRNDVSRIARTGTVRVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPCGSITGAPKHKTMQLIDAIES
TPRGLYTGAIGWLDAAKQGADSDAPGDRLAGCGDFCLSVAIRTLTLDAAGEGDDRGGATRADVEARQPATAIAGRRRGTM
GVGAGIVLDSVAADEYAECELKARFLTDADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDTDALRREIDAR
CAALDGDGAYRMKLSLAKDGTIEIVAAPLKPLPAGPVGVLLASAHGFAPTRTSDALLLHKTTRRAEYDRAWQAAEALGGF
DMLFVNERGEVTEGGRSNLFVKLDGQWVTPPLESGVLPGVMRGVLLDDRAFSATERVVTRDDLARAEALLLTNALRGALD
AVLK
>Mature_643_residues
TEGNESASFALLDDCDSTALARSSRLYSGFVRERVCTDPARLDEVDAAVAQDLRDGLHAVVVGDYEFGRNLQRAQPGHAP
LRFLLFARCERLSRDEVDAWLAQRDGGGTPSIAGVAHVAKSVSRDAFDVAIAAVHDALRAGDSYQVNYTYRLNFDVFGTP
LALYRRLRARQPVRYGALIALPDGTWVVSCSPELFVEKYGDVLRARPMKGTAPRSADPRDDAAAATFLANDPKNRAENVM
IVDLLRNDVSRIARTGTVRVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPCGSITGAPKHKTMQLIDAIEST
PRGLYTGAIGWLDAAKQGADSDAPGDRLAGCGDFCLSVAIRTLTLDAAGEGDDRGGATRADVEARQPATAIAGRRRGTMG
VGAGIVLDSVAADEYAECELKARFLTDADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDTDALRREIDARC
AALDGDGAYRMKLSLAKDGTIEIVAAPLKPLPAGPVGVLLASAHGFAPTRTSDALLLHKTTRRAEYDRAWQAAEALGGFD
MLFVNERGEVTEGGRSNLFVKLDGQWVTPPLESGVLPGVMRGVLLDDRAFSATERVVTRDDLARAEALLLTNALRGALDA
VLK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=276, Percent_Identity=35.5072463768116, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI1787518, Length=309, Percent_Identity=28.8025889967638, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1786809, Length=176, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=224, Percent_Identity=31.25, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324361, Length=239, Percent_Identity=31.3807531380753, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 69414; Mature: 69283

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGNESASFALLDDCDSTALARSSRLYSGFVRERVCTDPARLDEVDAAVAQDLRDGLHA
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEE
VVVGDYEFGRNLQRAQPGHAPLRFLLFARCERLSRDEVDAWLAQRDGGGTPSIAGVAHVA
EEEECHHHCCCHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
KSVSRDAFDVAIAAVHDALRAGDSYQVNYTYRLNFDVFGTPLALYRRLRARQPVRYGALI
HHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECEECCCHHHHHHHHHHCCCCCCCEEE
ALPDGTWVVSCSPELFVEKYGDVLRARPMKGTAPRSADPRDDAAAATFLANDPKNRAENV
EECCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCE
MIVDLLRNDVSRIARTGTVRVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPC
EEHHHHHHHHHHHHHCCCEEECEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
GSITGAPKHKTMQLIDAIESTPRGLYTGAIGWLDAAKQGADSDAPGDRLAGCGDFCLSVA
CCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHH
IRTLTLDAAGEGDDRGGATRADVEARQPATAIAGRRRGTMGVGAGIVLDSVAADEYAECE
HHHEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHE
LKARFLTDADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDTDALRREIDAR
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEECHHHHHHHHHHH
CAALDGDGAYRMKLSLAKDGTIEIVAAPLKPLPAGPVGVLLASAHGFAPTRTSDALLLHK
HEEECCCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHEECCCCCCCCCCCCEEEEEH
TTRRAEYDRAWQAAEALGGFDMLFVNERGEVTEGGRSNLFVKLDGQWVTPPLESGVLPGV
HHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEEECCEEECCCHHCCCCHHH
MRGVLLDDRAFSATERVVTRDDLARAEALLLTNALRGALDAVLK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEGNESASFALLDDCDSTALARSSRLYSGFVRERVCTDPARLDEVDAAVAQDLRDGLHA
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEE
VVVGDYEFGRNLQRAQPGHAPLRFLLFARCERLSRDEVDAWLAQRDGGGTPSIAGVAHVA
EEEECHHHCCCHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
KSVSRDAFDVAIAAVHDALRAGDSYQVNYTYRLNFDVFGTPLALYRRLRARQPVRYGALI
HHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECEECCCHHHHHHHHHHCCCCCCCEEE
ALPDGTWVVSCSPELFVEKYGDVLRARPMKGTAPRSADPRDDAAAATFLANDPKNRAENV
EECCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCE
MIVDLLRNDVSRIARTGTVRVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPC
EEHHHHHHHHHHHHHCCCEEECEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
GSITGAPKHKTMQLIDAIESTPRGLYTGAIGWLDAAKQGADSDAPGDRLAGCGDFCLSVA
CCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHH
IRTLTLDAAGEGDDRGGATRADVEARQPATAIAGRRRGTMGVGAGIVLDSVAADEYAECE
HHHEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHE
LKARFLTDADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDTDALRREIDAR
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEECHHHHHHHHHHH
CAALDGDGAYRMKLSLAKDGTIEIVAAPLKPLPAGPVGVLLASAHGFAPTRTSDALLLHK
HEEECCCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHEECCCCCCCCCCCCEEEEEH
TTRRAEYDRAWQAAEALGGFDMLFVNERGEVTEGGRSNLFVKLDGQWVTPPLESGVLPGV
HHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEEECCEEECCCHHCCCCHHH
MRGVLLDDRAFSATERVVTRDDLARAEALLLTNALRGALDAVLK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]