Click here to switch to the map view.

The map label for this gene is ubiA

Identifier: 78065291

GI number: 78065291

Start: 715401

End: 716264

Strand: Direct

Name: ubiA

Synonym: Bcep18194_A3815

Alternate gene names: 78065291

Gene position: 715401-716264 (Clockwise)

Preceding gene: 78065290

Following gene: 78065298

Centisome position: 19.37

GC content: 65.28

Gene sequence:

>864_bases
ATGCTTGCCCGCTTTCCCCTGTATCTGCGGCTCGTCCGGATGGACAAGCCGATCGGCAGCCTGCTGCTGCTGTGGCCGAC
GCTCAACGCGCTGTGGATTGCGTCCGACGGCCACCCGCGCTGGCCGCTGCTCGTGATCTTCTCGCTCGGCACGCTGCTGA
TGCGTTCGGCCGGCTGCGCGATGAACGACTACGCCGACCGCGATTTCGACCGCCACGTGAAGCGCACAGCCGACCGGCCG
CTGACGTCGGGCAAGATCCGCGCGTGGGAAGCCATCGCGATCGCGGTCGGGCTCGCATTCGTCTCGTTCCTGCTGATCCT
GCCGCTCAACACGCTGACGAAGCAGCTGTCCGTCGTCGCACTGTTCGTCGCGGGATCGTATCCGTTCATGAAGCGCTTCT
TCGCGATTCCGCAGGCGTATCTGGGCATCGCGTTCGGCTTCGGCATCCCGATGGCGTTCGCGGCCGTGCAGGACACGGTG
CCGACGATCGCGTGGGTGATGCTGATCGCGAACATTTTCTGGTCGGTCGCGTACGACACCGAATACGCGATGGTCGATCG
CGACGACGATATCAAGATCGGCATCCGTACGTCCGCGCTGACGTTCGGCCGCTTCGACGTCGCGGCCGTCATGCTGTGCT
ACGCGGTGACGCTCGGCATCTACGTATGGATCGGCGTGACGCTCGGTTTCGGCCTCGCGTACTGGGCCGGCTGGGCGGCG
GCGGTCGGCTGCGCGCTGTATCACTACACACTGATCAAGGACCGCGAGCGGATGCCGTGTTTCGCGGCATTCCGGCACAA
CAACTGGCTCGGCGGCGTGCTGTTCGCGGGGATTGCCGCGCATTACCTGCTGGCTGGGAGCTGA

Upstream 100 bases:

>100_bases
CGCGCCGGCGTTCGGCTGCTACCGCCCGCGAGCCGCGCCGACATGACGCGAAGCACCGCTCGGCTCTAAAATGCCGGGGT
TATCTTCCCGGTGCTTCGCC

Downstream 100 bases:

>100_bases
GCGTCCCGATCTGTCCGCCGGCGTCATGTCGTGCGGATCGCGGCAACAAAAAAAGCGGCCTGGGCCGCTTTTTTTGTTGG
TTGAGCAAGGCAAAGGGGGC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLVIFSLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAIAIAVGLAFVSFLLILPLNTLTKQLSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PTIAWVMLIANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAVTLGIYVWIGVTLGFGLAYWAGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGS

Sequences:

>Translated_287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLVIFSLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAIAIAVGLAFVSFLLILPLNTLTKQLSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PTIAWVMLIANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAVTLGIYVWIGVTLGFGLAYWAGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGS
>Mature_287_residues
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLVIFSLGTLLMRSAGCAMNDYADRDFDRHVKRTADRP
LTSGKIRAWEAIAIAVGLAFVSFLLILPLNTLTKQLSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PTIAWVMLIANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAVTLGIYVWIGVTLGFGLAYWAGWAA
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=275, Percent_Identity=34.1818181818182, Blast_Score=153, Evalue=2e-37,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=54.1818181818182, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17553718, Length=281, Percent_Identity=33.8078291814947, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32565247, Length=281, Percent_Identity=33.0960854092527, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17553720, Length=338, Percent_Identity=28.9940828402367, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=40.1459854014599, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=39.8496240601504, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324370, Length=290, Percent_Identity=28.6206896551724, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355567, Length=296, Percent_Identity=34.7972972972973, Blast_Score=140, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 31850; Mature: 31850

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLVIFSLGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
MNDYADRDFDRHVKRTADRPLTSGKIRAWEAIAIAVGLAFVSFLLILPLNTLTKQLSVVA
CCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPTIAWVMLIANIFWSVAYDT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAVTLGIYVWIGVTLGFGLAYWAGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGS
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLVIFSLGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHEEHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
MNDYADRDFDRHVKRTADRPLTSGKIRAWEAIAIAVGLAFVSFLLILPLNTLTKQLSVVA
CCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPTIAWVMLIANIFWSVAYDT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAVTLGIYVWIGVTLGFGLAYWAGWAA
EEEEECCCCCEEEEEEECEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGS
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA